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A Multicenter, Randomized, Controlled Trial for Assessing the Usefulness of Suppressing Thyroid Stimulating Hormone Target Levels after Thyroid Lobectomy in Low to Intermediate Risk Thyroid Cancer Patients (MASTER): A Study Protocol

Lee EK, Kang YE, Park YJ, Koo BS, Chung KW, Ku EJ, Won HR, Yoo WS, Jeon E, Paek SH, Lee YS, Lim DM, Suh YJ, Park HK, Kim HJ, Kim BH, Kim M, Kim SW, Yi KH, Park SK, Jung EJ, Choi JY, Bae JS, Hong JH, Nam KH, Lee YK, Yu HW, Go S, Kang YM, MASTER study group

Background: Postoperative thyroid stimulating hormone (TSH) suppression therapy is recommended for patients with intermediate- and high-risk differentiated thyroid cancer to prevent the recurrence of thyroid cancer. With the recent increase...
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Tumor Spheroids of an Aggressive Form of Central Neurocytoma Have Transit-Amplifying Progenitor Characteristics with Enhanced EGFR and Tumor Stem Cell Signaling

Shin HY, Han KS, Park HW, Hong YH, Kim Y, Moon HE, Park KW, Park HR, Lee CJ, Lee K, Kim SJ, Heo MS, Park SH, Kim DG, Paek SH

  • KMID: 2515812
  • Exp Neurobiol.
  • 2021 Apr;30(2):120-143.
  • doi: 10.5607/en21004
Central neurocytoma (CN) has been known as a benign neuronal tumor. In rare cases, CN undergoes malignant transformation to glioblastomas (GBM). Here we examined its cellular origin by characterizing differentiation...
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Long-term Outcome of Microscopic Transsphenoidal Surgery for Prolactinomas as an Alternative to Dopamine Agonists

Park K, Park KH, Park HR, Lee JM, Kim YH, Kim DY, Won TB, Kong SH, Kim JH, Shin CS, Paek SH

Background: Although long-term dopamine agonist (DA) therapy is recommended as a first-line treatment for prolactinoma, some patients may prefer surgical treatment because of the potential adverse effects of long-term medication,...
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Gender differences in characteristics of adolescents with suicide attempt at the emergency department

An YJ, Paek SH, Kim OJ, Kim JA, Kwon JH, Kim MJ

Purpose: This study was performed to investigate the gender differences in suicide attempts in adolescents. Methods: We reviewed the medical records of adolescents (≤ 18 years) who had visited a...
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Nipple-sparing mastectomy through periareolar incision with immediate reconstruction

Paek SH, Hong SE, Woo KJ, Woo J, Lim W

PURPOSE: Nipple-sparing mastectomy (NSM) has become increasingly popular due to improved cosmesis without compromising oncologic safety. Radial and inframammary incisions are usually used to achieve NSM, with periareolar incisions usually...
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Successful Pallidal Deep Brain Stimulation in a Patient with Childhood-Onset Generalized Dystonia with ANO3 Mutation

Yoo D, Kim HJ, Chae JH, Paek SH, Jeon B

No abstract available.
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The difference of Use of CT in the general versus pediatric emergency departments for adolescent patients in the same tertiary hospital

Kim SK, Jung JH, Lee JH, Jung JY, Kwon H, Paek SH, Kwak YH, Kim DK

OBJECTIVE: The use of computed tomography (CT) in pediatric patients has decreased since the association between radiation and cancer risk has been reported. However, in adolescent patients being treated as...
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Frameless Fractionated Gamma Knife Radiosurgery with ICONâ„¢ for Large Metastatic Brain Tumors

Park HR, Park KW, Lee JM, Kim JH, Jeong SS, Kim JW, Chung HT, Kim DG, Paek SH

BACKGROUND: Recently, a new generation of gamma knife radiosurgery (GKRS) equipped with a frameless immobilization system has encouraged the use of fractionated GKRS as an increasingly favorable treatment option. We...
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Circulating Plasmacytoid and Myeloid Dendritic Cells in Breast Cancer Patients: A Pilot Study

Paek SH, Kim HG, Lee JW, Woo J, Kwon H, Kim JB, Lim W, Kim JR, Moon BI, Paik NS

PURPOSE: Dendritic cells (DC) are a class of bone marrow-derived cells found in the blood, epithelia, and lymphoid tissues, and are the most efficient antigen presenting cells. The number and...
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Infratemporal fossa approach: the modified zygomatico-transmandibular approach

Kim SM, Paek SH, Lee JH

BACKGROUND: The infratemporal fossa (ITF) is an anatomical lateral skull base space composed by the zygoma, temporal, and the greater wing of the sphenoid bone. Due to its difficult approach,...
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Fractionated Gamma Knife Radiosurgery as Initial Treatment for Large Skull Base Meningioma

Park HR, Lee JM, Park KW, Kim JH, Jeong SS, Kim JW, Chung HT, Kim DG, Paek SH

We present our experience on the hypofractionated Gamma Knife radiosurgery (FGKS) for large skull base meningioma as an initial treatment. We retrospectively reviewed 23 patients with large skull base meningioma...
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Quality improvement activity for improving pain management in acute extremity injuries in the emergency department

Chang HL, Jung JH, Kwak YH, Kim DK, Lee JH, Jung JY, Kwon H, Paek SH, Park JW, Shin J

OBJECTIVE: The aim of this study was to investigate the effectiveness of a quality improvement activity for pain management in patients with extremity injury in the emergency department (ED). METHODS: This...
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Long-term changes in computed tomography and ultrasound utilization in a pediatric emergency department

Chang I, Jung JY, Kwak YH, Kim DK, Lee JH, Jung JH, Kwon H, Paek SH, Park JW

OBJECTIVE: Many studies have proposed reducing unnecessary use of computed tomography (CT), and ongoing studies in pediatric populations are aiming to decrease radiation dosages whenever possible. We aimed to evaluate...
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Clinical usefulness of intraoperative parathyroid hormone monitoring for primary hyperparathyroidism

Paek SH, Kim SJ, Choi JY, Lee KE

PURPOSE: The availability of intraoperative parathyroid hormone (IOPTH) monitoring allows successful focused parathyroidectomy for primary hyperparathyroidism (pHPT). The objective of this study was to report our initial experience in IOPTH...
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Feasibility of sentinel lymph node dissection using Tc-99m phytate in papillary thyroid carcinoma

Paek SH, Yi KH, Kim SJ, Choi JY, Lee KE, Park YJ, Park DJ, Kang KW, Chung JK

PURPOSE: Various methods of sentinel lymph node (SLN) biopsy in thyroid cancer have been introduced. Tc-99m phytate as a radiotracer has been successfully utilized for SLN biopsy in breast, cervix,...
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The Impact of Middle East Respiratory Syndrome Outbreak on Trends in Emergency Department Utilization Patterns

Paek SH, Kim DK, Lee JH, Kwak YH

Changes occurred in the patterns of utilization of emergency medical services during the Middle East respiratory syndrome (MERS) outbreak. The purpose of this study was to analyze the patterns of...
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Inhibition of HIF1α and PDK Induces Cell Death of Glioblastoma Multiforme

Han JE, Lim PW, Na CM, Choi YS, Lee JY, Kim Y, Park HW, Moon HE, Heo MS, Park HR, Kim DG, Paek SH

Glioblastoma multiforme (GBM) is the most common and aggressive form of brain tumors. GBMs, like other tumors, rely relatively less on mitochondrial oxidative phosphorylation (OXPHOS) and utilize more aerobic glycolysis,...
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High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients

Cho SY, Park C, Na D, Han JY, Lee J, Park OK, Zhang C, Sung CO, Moon HE, Kim Y, Kim JH, Kim JJ, Khang SK, Nam DH, Choi JW, Suh YL, Kim DG, Park SH, Youn H, Yun K, Kim JI, Lee C, Paek SH, Park H

Gliosarcoma (GS) is a rare variant (2%) of glioblastoma (GBM) that poses clinical genomic challenges because of its poor prognosis and limited genomic information. To gain a comprehensive view of...
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Effect of fermented soybean products intake on the overall immune safety and function in mice

Lee JH, Paek SH, Shin HW, Lee SY, Moon BS, Park JE, Lim GD, Kim CY, Heo Y

Various functional activities have been reported for the fermented soybean products doenjang (DJ) and cheonggukjang (CGJ), although no systemic investigations of their immune functions have been conducted to date. We...
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Endoscopic Thyroidectomy Via the Cervico-axillary Approach for Thyroid Cancer: Initial Experience in a Single Institute

An JS, Kim HG, Paek SH, Lee JW, Woo J, Kwon H, Lim W, Moon BI, Paik NS

PURPOSE: Endoscopic thyroidectomy using a cervico-axillary approach (CAA) provides optimal visualization with a smaller dissection plane. Despite the excellent cosmetic results and high patient satisfaction, the surgical and oncologic safety...
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