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J Korean Med Sci.  1998 Feb;13(1):99-102. 10.3346/jkms.1998.13.1.99.

A case of central pontine and extrapontine myelinolysis with early hypermetabolism on 18FDG-PET scan

Affiliations
  • 1Department of Neurology, Seoul National University Hospital, Korea.

Abstract

We report a 63 year-old woman who developed central pontine and extrapontine myelinolysis after rapid correction of hyponatremia. Lesions on brain MRI showed hypermetabolism on 18FDG-PET scan in the early stage of the disease and became hypometabolic on the follow-up scan. We suggest that active microglia and astrocytes are the main cause of the increased glucose metabolism.


MeSH Terms

Brain/pathology
Brain/metabolism*
Case Report
Female
Glucose/metabolism*
Human
Magnetic Resonance Imaging
Middle Age
Myelinolysis, Central Pontine/physiopathology
Myelinolysis, Central Pontine/pathology
Myelinolysis, Central Pontine/metabolism*
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