J Korean Acad Rehabil Med.
2007 Feb;31(1):119-112.
Secondary Parkinsonism due to Extrapontine Myelinolysis without Central Pontine Myelinolysis: A case report
- Affiliations
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- 1Department of Rehabilitation Medicine, Pusan National University College of Medicine, Korea. kulu73@medimail.co.kr
- 2Department of Rehabilitation Medicine,Pusan Medical Center, Korea.
Abstract
- Parkinsonism is characterized by clinical symptoms of rigidity, bradykinesia, tremor, and gait disturbance. There are many causes of secondary parkinsonism. The present report discusses a secondary parkinsonism of extrapontine myelinolysis (EPM) without central pontine myelinolysis (CPM) after rapid correction of hyponatremia. EPM is a demyelinating process of the brain. EPM with CPM is relatively common, but EMP without CPM is rare. A 57- year-old woman with Tsutsugamushi disease had a subacuteonset of parkinsonism on the fourteenth day after a rapid correction of severe hyponatremia. Magnetic resonance imaging of the bilateral basal ganglia showed a high signal intensity on T2-weighted images, and a low signal on T1- weighted images. She was started on levodopa, and parkinsonian features slowly improved. We report an unusual case of EPM without CPM, that presented with parkinsonism.
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