J Korean Radiol Soc.  1972 Jun;8(2):95-100. 10.3348/jkrs.1972.8.2.95.

Rickets

Abstract

Rickets is known as rare disease nowadays. Among 269,649 concerned clinic patients in 6 and one half yearssince 1965 to june 1971 at Yonsei University Severance Hospital, there were 33 cases of various rickets with annual increasing rate since 1968. Compared to the 1965 and previous years to 1968 almost 5 times increase innumber noted. The incidence of rickets was 8171:1 and ratio was 0.012 percent. There was none specific sex difference. The analysis of rickets disclosed vitamin D deficient type to be highest incidence of 90.9 percent. The rest was 3.03 percent each of vitamin D resistant rickets, renal rickets, and infantile tetany. Among 33 cases of rickets X-ray study was done in 24 cases of 72.7%. All showed positive rachitic bony changes. Blood chemistry disclosed elevated alkaline phosphatase generally but serum phosphorus and calcium was supportive evidence forrickets due to overlap with other diseases of malabsorption, starvation and vomiting in low srum phosphorus evenin high alkaline phosphatase differentiation should be made in fracture of bone, hyperparathyroidism andmetastatic bone disease however these factor can be eliminated some extend to the age prevalence in childhood of rickets. In X-ray study of among 24 cases, 21 (87.5%) of knee joints disclosed metaphyseal ricketic bony changes. And 13(54.1%) cases in wrists, 11(45.8%) in ankles, 7(29.1%) in long bone and 12(50%) in pelvis all show rachitic changes in 100 percent, however, in thoracic cage of 12 cases of half only disclosed rosary, and 2 (8.3%) loosezones. Therefore X-ray study still stands best aid for diagnostic value in rickets.

Keyword

Bones, mineralization; Rickets

MeSH Terms

Alkaline Phosphatase
Ankle
Bone Diseases
Calcium
Chemistry
Familial Hypophosphatemic Rickets
Humans
Hyperparathyroidism
Incidence
Knee Joint
Pelvis
Phosphorus
Prevalence
Rare Diseases
Renal Osteodystrophy
Rickets*
Sex Characteristics
Starvation
Tetany
Vitamin D
Vomiting
Wrist
Alkaline Phosphatase
Calcium
Phosphorus
Vitamin D
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