J Korean Pediatr Soc.  1997 Jul;40(7):1026-1030.

A Case of Infectious Mononucleosis Associated with Pleural Effusion and Ascites

Affiliations
  • 1Department of Pediatrics, College of Medicine, Inha University, Inchon, Korea.

Abstract

Infectious mononucleosis is an acute infectious disease occurring predominantly in older children and young adults due to primary Epstein-Barr virus infection. The clinical picture is extremely variable in both severity and duration. The disease in children is generally mild. It is characterized clinically by fever, exudative or membranous pharyngitis, generalized lymphadenopathy, and splenomegaly. Rarely, it complicates neurologic involvement such as cranial nerve palsy, meningoencephalitis, and transverse myelitis, hematologic involvement such as hemolytic anemia, immune thrombocytopenic purpura, and aplastic anemia, rupture of spleen, myocarditis, interstitial pneumonia, and orchitis, etc. We experienced a case of infectious mononucleosis with pleural effusion and ascites in a 5-year-old male with the chief complaint of fever, sore throat and vomiting 3 days prior to admission. The diagnosis was made on the clinical findings, immunologic findings and the typical findings of peripheral blood smear. On peripheral blood smear, leukocytosis with atypical lymphocytosis were seen. On immunologic study, anti-VCA IgM and IgG were positive by ELISA method. We reported this case and reviewed related literatures briefly.

Keyword

Infectious mononucleosis; Pleural effusion; Ascites

MeSH Terms

Anemia, Aplastic
Anemia, Hemolytic
Ascites*
Child
Child, Preschool
Communicable Diseases
Cranial Nerve Diseases
Diagnosis
Enzyme-Linked Immunosorbent Assay
Fever
Herpesvirus 4, Human
Humans
Immunoglobulin G
Immunoglobulin M
Infectious Mononucleosis*
Leukocytosis
Lung Diseases, Interstitial
Lymphatic Diseases
Lymphocytosis
Male
Meningoencephalitis
Myelitis, Transverse
Myocarditis
Orchitis
Pharyngitis
Pleural Effusion*
Purpura, Thrombocytopenic, Idiopathic
Rupture
Spleen
Splenomegaly
Vomiting
Young Adult
Immunoglobulin G
Immunoglobulin M
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