J Korean Rheum Assoc.  2000 Sep;7(3):286-290.

Facial Palsy as a Presenting Symptom of Wegener's Granulomatosis

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

Wegener's granulomatosis is a serious multi-systemic disease pathologically characterized by necrotizing vasculitis and granuloma. Although nervous system is one of major target organs in Wegener's granulomatosis, the involvement of facial nerve was rarely reported as an initial symptom. We experienced a female patient with Wegener's granulomatosis presenting otitis media, sinusitis and right facial palsy. Nasal mucosal biopsy revealed necrotizing vasculitis with granuloma formation, which was consistent with Wegener's granulomatosis. During steroid and cyclophosphamide therapy, she developed paralysis of abducens nerve. Methyprednisolone pulse therapy was administrated with symptomatic improvement. We describe a case of Wegener's granulomatosis presenting facial nerve palsy.

Keyword

Wegener's granulomatosis; Cranial nerve paralysis; Facial palsy

MeSH Terms

Abducens Nerve
Biopsy
Cyclophosphamide
Facial Nerve
Facial Paralysis*
Female
Granuloma
Humans
Nervous System
Otitis Media
Paralysis
Sinusitis
Vasculitis
Wegener Granulomatosis*
Cyclophosphamide
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