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Role of IL-17A in Chronic Rhinosinusitis With Nasal Polyp

Ryu G, Bae JS, Kim JH, Kim EH, Lyu L, Chung YJ, Mo JH

PURPOSE: Th17-associated inflammation is increased in chronic rhinosinusitis with nasal polyp (CRSwNP), and is associated with disease severity and steroid resistance. Overexpressed interleukin (IL)-17A affects CRSwNP by tissue remodeling, eosinophilic...
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Evaluation of Neo-Osteogenesis in Eosinophilic Chronic Rhinosinusitis Using a Nasal Polyp Murine Model

Khalmuratova R, Lee M, Park JW, Shin HW

PURPOSE: Osteitis refers to the development of new bone formation and remodeling of bone in chronic rhinosinusitis (CRS) patients; it is typically associated with eosinophilia, nasal polyps (NPs), and recalcitrant...
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MR Findings of Fungus Ball: Significance of High Signal Intensity on T1-Weighted Images

Kim SC, Ryoo I, Shin JM, Suh S, Jung HN, Shin SU

BACKGROUND: Central dark-signal intensity with high-signal, hypertrophic mucosal wall of paranasal sinuses on T2-weighted images (T2WI) is a characteristic magnetic resonance imaging (MRI) feature of sinonasal fungus ball. However, this...
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Elastase-Positive Neutrophils Are Associated With Refractoriness of Chronic Rhinosinusitis With Nasal Polyps in an Asian Population

Kim DK, Kim JY, Han YE, Kim JK, Lim HS, Eun KM, Yang SK, Kim DW

PURPOSE: Various immune cells, including eosinophils and neutrophils, are known to contribute to the development of chronic rhinosinusitis with nasal polyps (CRSwNP). However, the current understanding of the role of...
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Dentistry and otorhinolaryngology cooperative therapy of chronic maxillary sinusitis: Case series study

Yu HC, Yun PY, Chang NH, Kim YK

For the maxillary sinus to normally function, the ventilation and drainage should be well maintained. The natural ostium of the maxillary sinus could be blocked owing to various reasons. In...
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Oculomotor and Abducens Nerve Palsy Complicated by Cavernous Sinus Thrombophlebitis Resulting from Acute Sinusitis

Kang JY, Kim JJ, Choi IJ, Lee MC

Cavernous sinus thrombophlebitis is a rare complication of paranasal sinusitis. The disease can result in a fatal outcome if not treated with proper antibiotics or surgical intervention. Recently, we experienced...
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Points to consider before the insertion of maxillary implants: the otolaryngologist's perspective

Kim SW, Lee IH, Kim SW, Kim DH

Maxillary implants are inserted in the upward direction, meaning that they oppose gravity, and achieving stable support is difficult if the alveolar bone facing the maxillary sinus is thin. Correspondingly,...
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Analysis of Treatment Outcome Associated with Pre-Operative Diagnostic Accuracy Changes and Dental Treatment Timing in Odontogenic Sinusitis Involving Unilateral Maxillary Sinus

Choi KY, Mo JH, Chung YJ

BACKGROUND AND OBJECTIVES: Unilateral sinusitis is caused by various factors. Odontogenic sinusitis; especially, is different from non-odontogenic sinusitis in clinical features and prognosis. The purpose of this study is to...
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Two Cases of Actinomycosis with Aspergillosis in Unilateral Paranasal Sinuses

Min HK, Kwon OE, Min JY, Kim SW

Actinomycosis of paranasal sinus is a very rare disease that is caused by infection of Actinomyces species that were present in oral or nasal flora due to trauma or dental...
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Invasive Pneumococcal Disease Caused by Non-Vaccine Type Multidrug-Resistant Streptococcus pneumoniae Transmitted by Close Contact in a Healthy Adult

Yoo JR, Oh S, Lee JG, Kim YR, Lee KH, Heo ST

The incidence of vaccine-type Streptococcus pneumoniae carriage and disease have declined in vaccinated children as well as in unvaccinated children and adults. However, diseases caused by non-vaccine type (NVT) S....
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The Role of NF-κB in Chronic Rhinosinusitis With Nasal Polyps

Jung HJ, Zhang YL, Kim DK, Rhee CS, Kim DY

PURPOSE: Whereas the majority of nasal polyps observed in Western populations are eosinophilic, non-eosinophilic nasal polyps are significantly more frequent in Asian countries. Given the importance of nuclear factor-kappa B...
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Two Cases of Bilateral Paranasal Sinus Fungus Balls with Sphenoid Sinus Involvement

Lee WH, Ryu YJ, Won JY, Hwang J

A fungus ball is the most common manifestation of fungal sinusitis. Bilateral involvement of fungus balls is rare, and bilateral sphenoid involvement is even more uncommon. The authors report two...
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Delayed intraorbital infection after craniofacial bone surgery

Jung JS, Lim NK, Kang DH

Intraorbital infection shows a low incidence, but it might cause blindness or even death. This case is unusual in that its origin from a craniofacial bone fracture prior to infection...
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In-Depth, Proteomic Analysis of Nasal Secretions from Patients With Chronic Rhinosinusitis and Nasal Polyps

Kim YS, Han D, Kim J, Kim DW, Kim YM, Mo JH, Choi HG, Park JW, Shin HW

PURPOSE: Chronic rhinosinusitis (CRS) is a complex immunological condition, and novel experimental modalities are required to explore various clinical and pathophysiological endotypes; mere evaluation of nasal polyp (NP) status is...
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Immunological Characteristics in Refractory Chronic Rhinosinusitis with Nasal Polyps Undergoing Revision Surgeries

Ryu G, Kim DK, Dhong HJ, Eun KM, Lee KE, Kong IG, Kim H, Chung SK, Kim DY, Rhee CS, Cho SH, Hong SD, Kim DW

PURPOSE: Despite medical and surgical treatments, some cases of nasal polyps (NP) exhibit recidivism. However, the endotype of refractory chronic rhinosinusitis with NP (CRSwNP) remains unclear. Therefore, the objective of...
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Biomarkers in Chronic Rhinosinusitis with Nasal Polyp: Personalized Medicine Based on Endotype

Song Y, Cho SW

Chronic rhinosinusitis (CRS) is divided into CRS with nasal polyp (CRSwNP) and CRS without nasal polyp (CRSsNP) according to the presence of a nasal polyp. Some of the CRSwNP patients...
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Epidural Abscess Caused by Eikenella corrodens in a Previously Healthy Child

Kim YK, Han MS, Yang SI, Yun KW, Han DH, Kim JY, Choi EH

Eikenella corrodens rarely causes invasive head and neck infections in immunocompetent children. We report a case of epidural abscess caused by E. corrodens in a previously healthy 13-year-old boy who...
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Headache with Ptosis Attributed to Fungal Sinusitis

Kim Y, Lee HC, Park SP, Seo JG

No abstract available.
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Eosinophilic Granulomatosis with Polyangiitis: Experiences in Korean Patients

Choi CB, Park YB, Lee SW

Eosinophilic granulomatosis with polyangiitis (EGPA) is one form of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Identical to what has been called Churg-Strauss syndrome, EGPA exhibits both allergic and vasculitis features. EGPA...
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The Differences in Paranasal Sinus Pneumatization after Adolescence in Korean

Kang M, Mo JH, Chung YJ

BACKGROUND AND OBJECTIVES: The embryological development of paranasal sinuses has been revealed by previous articles although few studies have reported on the differences of paranasal sinus pneumatization according to age...
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