J Korean Soc Endocrinol.  1999 Mar;14(1):171-176.

A Case of Parathyroid Carcinoma Invading Thyroid Gland as Solitary Nodular Form

• Choi YK
• Lee JS
• Kim HW
• Kim YM
• Son SM
• Kim IJ
• Kim YK
• Chae HJ

Abstract

Parathyroid carcinoma is a rare cause of primary hyperparathyroidism and commonly metastasize to lymph node, lung, liver, and bone. In Korea, there has been no report of distant metastasis in parathyroid carcinoma except for one case of pulmonary metastasis. A 58-year-old man presenting with weakness, nausea, and a palpable thyroid nodule visited our hospital. Elevated serum calcium and parathyroid hormone (PTH) concentration allowed the diagnosis of hyperparathyroidism. Two discrete masses were identified by neck ultrasound scan, computed tomography (CI') and Tc-Sestamibi scan in the left lobe of thyroid gland and ipsilateral parathyroid gland. So multiple endocrine neoplasia (MEN) type 2A" was suspected initially, but postoperative histological diagnosis was left parathyroid carcinoma with solitary nodular lesion invading left thyroid gland. He was successfully treated with left parathyroidectomy and left thyroid lobectomy.

MeSH Terms

Calcium
Diagnosis
Humans
Hyperparathyroidism
Hyperparathyroidism, Primary
Korea
Liver
Lung
Lymph Nodes
Middle Aged
Multiple Endocrine Neoplasia
Multiple Endocrine Neoplasia Type 2a
Nausea
Neck
Neoplasm Metastasis
Parathyroid Glands
Parathyroid Hormone
Parathyroid Neoplasms*
Parathyroidectomy
Thyroid Gland*
Thyroid Nodule
Ultrasonography
Calcium
Parathyroid Hormone