Int J Thyroidol.  2015 Nov;8(2):194-197. 10.11106/ijt.2015.8.2.194.

Thyroid Hemiagenesis Associated with Papillary Carcinoma

• Oh JS
• Hong KH
• Yoon YS

• KMID: 2171229
• DOI: http://doi.org/10.11106/ijt.2015.8.2.194

Abstract

This paper reports a rare case of a left sided thyroid hemiagenesis associated with papillary carcinoma. Thyroid hemiagenesis is a rare congenital anomaly resulted from failure of development on one of the thyroid lobes. Among several thyroid developmental anomalies, hemiagenesis is considered to be the rarest anomaly. In world literature to date, only about 310 cases have been reported. We present a case of thyroid hemiagenesis of the left lobe and isthmus in a 51-year-old female, along with radiological and operative findings. Our report can give the idea that the thyroid hemiagenesis may not influence the development of parathyroid glands.

Keyword

Thyroid gland; Hemiagenesis; Carcinoma

MeSH Terms

Carcinoma, Papillary*
Female
Humans
Middle Aged
Parathyroid Glands
Thyroid Gland*

Figure

• 

  Fig. 1. (A) A CT scan of neck showing left hemiage-nesis and multiple nodules on the right thyroid. (B) A neck ultrasound showing left thyroid hemiagenesis. Ope-rative finding revealing left thyroid hemiagenesis with isthmus agenesis (C) and existence of the pyramidal lobe (arrow) (D).

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  Fig. 2. (A) An operative ima-ge taken just before the right thyroid lobectomy. (B) An image showing left parath-yroid glands in normal po-sition (arrows). (C) A picture of the specimen after the operation. Note that left lobe and isthmus of the thyroid is absent. (D) Pathologic finding showed enlarged tumor cells with intranuclear pseudo in-clusions (arrows). Original mag-nification ×400.

Reference

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