J Korean Acad Rehabil Med.  2009 Oct;33(5):632-634.

Multiple Lumbar Compression Fractures due to Hypopituitarism as a Late Complication of Hemorrhagic Fever with Renal Syndrome: A case report

• You SD
• Kim DH
• Huh KY
• Yoo BS
• Choi SH

Abstract

Male osteoporosis is known to progress slowly and is less severe compared to female osteoporosis, and the incidence of lumbar compression fracture is considerably lower in male population. Hypogonadism which can develop from various causes including hypopituitarism is a common cause for secondary male osteoporosis. Hypopituitarism as a late complication of severe form of hemorrhagic fever with renal syndrome (HFRS) is known to occur occasionally but its clinical symptoms rarely appear. A 75-year-old male patient who had recovered from HFRS 13 years ago was admitted due to severe low back pain. He presented with gradually developed symptoms of hypogonadism and hypothyroidism resulting from hypopituitarism. MRI revealed collapsed pituitary gland and empty sella. This case presents with a male patient with multiple lumbar compression fractures due to severe osteoporosis secondary to hypogonadism, which resulted from hypopituitarism as a late complication of HFRS.

Keyword

Hypopituitarism; Hemorrhagic fever with renal syndrome; Osteoporosis; Osteoporosis

MeSH Terms

Aged
Female
Fever
Fractures, Compression
Hemorrhagic Fever with Renal Syndrome
Humans
Hypogonadism
Hypopituitarism
Hypothyroidism
Incidence
Low Back Pain
Male
Osteoporosis
Pituitary Gland