J Korean Surg Soc.  2013 May;84(5):309-311.

Heterotopic pancreas of the gallbladder associated with segmental adenomyomatosis of the gallbladder

  • 1Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Busan, Korea. seohi71@hanmail.net


Heterotopic pancreas in the gallbladder is extremely rare and usually incidentally discovered at the pathologic examination followed by cholecystectomy for symptomatic gallbladder disease. Up to the presents, only about 30 cases have been reported. We report the case of a 36-year-old female who presented with symptoms of cholecystitis. The histological analysis followed by cholecystectomy revealed heterotopic pancreas of the cystic duct.


Heterotopic pancreas; Gallbladder; Cholecystitis

MeSH Terms

Cystic Duct
Gallbladder Diseases


  • Fig. 1 Preoperative computed tomography findings. Mild gallbladder (GB) wall thickening is observed.

  • Fig. 2 Preoperative computed tomography findings. Cystic duct abnormalities are not observed.

  • Fig. 3 Adenomatous hyperplasia was present on the body of the gallbladder (H&E, ×40).

  • Fig. 4 The pancreatic duct lays on the muscle layer of the cystic duct (red arrow) and the pancreatic lobules are grouped on the subserosa (black arrow) (H&E, ×12.5).

  • Fig. 5 On high power microscopy, the lobules contain acini and islets in normal proportions (H&E, ×40).


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