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Association of Microbial Dysbiosis with Gallbladder Diseases Identified by Bile Microbiome Profiling

Choi SJ, Kim Y, Jeon J, Gwak HJ, Kim M, Kang K, Kim Y, Jeong J, Jung YK, Lee KG, Choi HS, Jung DH, Lee SG, Lee Y, Shin SJ, Jang K, Rho M, Choi D

Background: Cholecystitis is an important risk factor for gallbladder cancer, but the bile microbiome and its association with gallbladder disease has not been investigated fully. We aimed to analyze the bile...
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Four-Step Classification of Endoscopic Transpapillary Gallbladder Drainage and the Practical Efficacy of Cholangioscopic Assistance

Yoshida M, Naitoh I, Hayashi K, Jinno N, Hori Y, Natsume M, Kato A, Kachi K, Asano G, Atsuta N, Sahashi H, Kataoka H

Background/Aims: Although endoscopic transpapillary gallbladder drainage (ETGBD) has been reported as an alternative procedure for acute cholecystitis, it requires advanced endoscopic techniques. In terms of the certainty of achieving drainage,...
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Serum level of visfatin can reflect the severity of inflammation in patients with acute cholecystitis

Park JW, Kim OH, Lee SC, Kim KH, Hong HE, Seo H, Choi HJ, Kim SJ

Purpose: Visfatin is a key cytokine released from the pe ripheral blood mononuclear cells (PBMCs) as well as adipose tissue, and it is involved in immune response as well as...
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Clinical Safety of Laparoscopic Cholecystectomy in Elderly Patients: A Comparison of Clinical Outcomes in Patients Aged 65 to 79 Years and over 80 Years

Kim S, Choi N, Shin M, Jung D

Purpose: The safety and efficacy of laparoscopic cholecystectomy (LC) in elderly patients is a matter of concern because morbidity and clinical risk are higher in elderly patients; and some clinicians...
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Current Status in the Treatment of Acute Cholecystitis Patients Receiving Antithrombotic Therapy: Is Endoscopic Drainage Feasible?- A Systematic Review

Sagami R, Hayasaka K, Nishikiori H, Harada H, Amano Y

The bleeding complication risk of surgery or percutaneous transhepatic gallbladder drainage (PTGBD) may increase in patients with acute cholecystitis receiving antithrombotic therapy (ATT). Endoscopic gallbladder drainage (EGBD) may be recommended...
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A New Technique of Endoscopic Transpapillary Gallbladder Drainage Combined with Intraductal Ultrasonography for the Treatment of Acute Cholecystitis

Sagami R, Hayasaka K, Ujihara T, Nakahara R, Murakami D, Iwaki T, Suehiro S, Katsuyama , Harada H, Amano Y

Background/Aims: Endoscopic transpapillary gallbladder drainage (ETGBD) is useful for the treatment of acute cholecystitis; however, the technique is difficult to perform. When intraductal ultrasonography (IDUS) is combined with ETGBD, the...
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Endoscopic Transpapillary Gallbladder Stenting for Acute Cholecystitis in a Patient with Metastatic Pancreatic Cancer

Nam SH, Baek SH, Yoo DR, Choi SJ, Lee JS, Oh D, Kim MH

Percutaneous transhepatic gallbladder drainage is an effective treatment for acute cholecystitis in poor surgical candidates. Endoscopic gallbladder drainage procedures, such as endoscopic ultrasound-guided gallbladder drainage, endoscopic gallbladder stenting, and endoscopic...
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Acute Acalculous Cholecystitis Associated with Sunitinib Treatment for Renal Cell Carcinoma

Choi SW, Lee JM, Kim DG, Noh MH

A 64-year-old man was treated with sunitinib as a first-line therapy for metastatic renal cell carcinoma. He was given oral sunitinib in cycles of 50 mg once daily for 2...
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Practical Approaches for High-Risk Surgical Patients with Acute Cholecystitis: The Percutaneous Approach versus Endoscopic Alternatives

Rerknimitr R, Pham KC

In high-risk surgical patients with acute cholecystitis who are not candidates for early laparoscopic cholecystectomy, gallbladder (GB) drainage is an alternative treatment option. Percutaneous transhepatic gallbladder drainage (PTGBD) is a...
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Recent development of endoscopic ultrasound-guided gallbladder drainage

Hang Lam BK, Bun Teoh AY

Endoscopic ultrasonography-guided gallbladder drainage (EUS-GBD) has emerged as a promising alternative treatment to high-risk patients suffering from acute cholecystitis and are unfit for surgery. EUS-GBD has similar rates of technical...
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Xanthogranulomatous cholecystitis: a rare gallbladder pathology from a single-center perspective

Saritas AG, Gul MO, Teke Z, Ulku A, Rencuzogullari A, Aydin I, Akcam AT

Purpose: The aim of this study was to review patients with xanthogranulomatous cholecystitis (XGC). Methods: A total of 79 patients diagnosed with XGC were included in the study. The criteria for...
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Added value of 2D shear wave imaging of the gallbladder bed of the liver for acute cholecystitis

Ko A, Lee ES, Park HJ, Park SB, Kim HS, Choi BI

Purpose: The purpose of this study was to evaluate whether shear wave elastography (SWE) and the shear wave dispersion slope (SWD) obtained from 2-dimensional shear wave imaging (2D-SWI) of the...
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Focal Xanthogranulomatous Pyelonephritis Associated with Xanthogranulomatous Cholecystitis: A Case Report

Cho SM, Kim HK, Lee HK, Lee B, Kim KH, Lee KE, Shim JC, Hwang DH, Lee GJ

Xanthogranulomatous inflammation is a rare inflammatory reaction, characterized by lipid-laden macrophages, known as xanthomas, in histopathologic examination. Aggressive xanthogranulomatous inflammation often manifests as local infiltration but does not affect distant...
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Acalculous cholecystitis associated with Hantaan virus: A case report

Kim SH, Park S, Choi J

Acute acalculous cholecystitis (AAC) still remains one of the most elusive diagnoses and occurs in various conditions. Although AACs caused by viral infections are rare, various viruses have been revealed...
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Acute cholecystitis in neutropenic patients

Clemente-Gutiérrez U, Sánchez Morales GE, Moctezuma Velazquez P, Rueda de León Aguirre A, Morales Maza J, Dominguez-Rosado I, Medina-Franco H

BACKGROUNDS/AIMS: The frequency of acute cholecystitis reported in neutropenic patients is between 0.4–1.65%. Clinical manifestations differ from general population as well as clinical approach, diagnosis and treatment. The aim of...
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Predictive factors for gangrene complication in acute calculous cholecystitis

Shirah BH, Shirah HA, Saleem MA, Chughtai M, Elraghi MA, Shams ME

BACKGROUNDS/AIMS: Gallbladder gangrene is a grave complication of acute calculous cholecystitis that is difficult to detect preoperatively. Ultrasound could show a gallbladder wall that is more thickened. In addition, other...
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Utility of liver function tests in acute cholecystitis

Zgheib H, Wakil C, Shayya S, Mailhac A, Al-Taki M, El Sayed M, Tamim H

BACKGROUNDS/AIMS: Common bile duct stones (CBDS) affect the management of acute cholecystitis (AC). This study aims to investigate the utility of liver function tests (LFTs) in predicting the presence of...
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Endoscopic Ultrasonography-Guided Gallbladder Drainage as a Treatment Option for Acute Cholecystitis after Metal Stent Placement in Malignant Biliary Strictures

Kozakai F, Kanno Y, Ito K, Koshita S, Ogawa T, Kusunose H, Masu K, Sakai T, Murabayashi T, Yonamine K, Kawakami Y, Fujii Y, Miyamoto K, Noda Y

BACKGROUND/AIMS: It is often difficult to manage acute cholecystitis after metal stent (MS) placement in unresectable malignant biliary strictures. The aim of this study was to evaluate the feasibility of...
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Conversion of percutaneous cholecystostomy to transmural endoscopic ultrasound-guided gallbladder drainage in malignant biliary obstruction

Kan M, Hashimoto , Shibuki T, Kimura G, Umemoto K, Watanabe K, Sasaki M, Takahashi , Imaoka H, Ohno I, Mitsunaga , Ikeda M

BACKGROUND: In patients with distal malignant biliary obstruction, it is a challenge to manage acute cholecystitis secondary to cystic duct obstruction associated with tumor progression or stent compression. Percutaneous transhepatic...
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Clonorchis sinensis Infection Presenting as Acute Cholangitis and Acute Cholecystitis

Yang YM, Choi H, Ryu DH, Woo CG, Han JH, Park SM

A 59-year-old woman presented with abdominal pain. Abdominal computerized tomography was suggestive of biliary stones. During endoscopic retrograde cholangiopancreatography, adult worms resembling Clonorchis sinensis (C. sinensis) were drained. Eggs were...
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