Psychiatry Investig.  2015 Jul;12(3):408-410. 10.4306/pi.2015.12.3.408.

The Joint Effects of Body Mass Index and MAOA Gene Polymorphism on Depressive Symptoms

Affiliations
  • 1Department of Psychology, Nanjing University, Nanjing, China. Liuyangyang661@sina.com

Abstract

The objective of the present study was to examine the joint effects of the body mass index and the MAOA gene polymorphism on depressive symptoms. In two independent Chinese samples, we measured adolescents' depressive symptoms and body mass index and collected their DNA. The results indicated that the main effects of the MAOA gene polymorphism on depressive symptoms were significant. However, the main effects of body mass index and the interaction of the MAOA gene polymorphism and body mass index on depressive symptoms were not significant. By using Chinese adolescents, this study confirmed that the MAOA gene polymorphism directly influenced adolescents' depressive symptoms.

Keyword

Body mass index; MAOA; Depressive symptoms; Chinese

MeSH Terms

Adolescent
Asian Continental Ancestry Group
Body Mass Index*
Depression*
DNA
Humans
Joints*
DNA
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