Korean J Urol.  2013 Apr;54(4):274-276.

Malacoplakia of the Epididymis

Affiliations
  • 1Department of Urology, Dongguk University College of Medicine, Gyeongju, Korea. honda400@dreamwiz.com
  • 2Department of Radiology, Dongguk University College of Medicine, Gyeongju, Korea.

Abstract

Malacoplakia is a chronic inflammatory disease. The disease mainly affects the urinary bladder, although involvement of extravesical sites is increasingly being documented. Most frequently involved is the urinary tract, particularly the urinary bladder, although the testis, epididymis, lungs, bone, colon, prostate, female genital organs, and retroperitoneum can also be involved. Here we report the case of a 61-year-old man with a scrotal mass with histology that was specific for malacoplakia of the epididymis. The histologic workup demonstrated extensive involvement of the epididymis by diffuse infiltrates of large histiocytes with eosinophilic granular cytoplasm and numerous Michaelis-Gutmann bodies, which were diagnostic of malakoplakia. This is the first case of epididymal malacoplakia in our country and the first case of epididymal malacoplakia without concurrent involvement of the testis. There have been few reports of this condition worldwide.

Keyword

Epididymis; Malacoplakia

MeSH Terms

Colon
Cytoplasm
Eosinophils
Epididymis
Female
Genitalia, Female
Histiocytes
Lung
Malacoplakia
Male
Prostate
Testis
Urinary Bladder
Urinary Tract

Figure

  • FIG. 1 Ultrasonography showed a mass lesion of mixed echotexture in epididymal tail.

  • FIG. 2 Epididymal mass show numerous histiocytes and Michaelis-Gutmann bodies (arrow) (H&E, ×400).


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