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Gastric Xanthoma in the Pediatric Population: A Possible Herald for Malignancy?

Russell JD, Peck J, Phen C, Linehan JL, Karjoo S, Nguyen J, Wilsey MJ

Gastric xanthoma is frequently an incidental finding on upper endoscopy in adults. Gastric xanthomas (GX) can be mistaken for malignancies and warrant prompt histologic diagnosis. The underlying etiology is not...
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Primary Histiocytic Sarcoma Presenting as a Breast Mass: A Case Report

Bang S, Kim Y, Chung MS, Park JS, Choi YY, Shin SJ

Histiocytic sarcoma is a rare hematologic malignancy, with very few cases of primary histiocytic sarcoma of the breast described in English scientific literature. Herein, we describe a case of primary...
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A Case of Rosai-Dorfman Disease Presented with Neck Mass

Yoon HS, Kim DH, Kim MS, Ji YB

Rosai-Dorfman disease, also known as the sinus histiocytosis with massive lymphadenopathy, is a rare and benign histioproliferative disease in which lymphadenopathy results from infiltration and dilatation of lymph node sinuses...
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Adult Xanthogranuloma: A Clinical, Histopathological, and Immunohistochemical Study of 19 Korean Cases

Kwak HB, Jung ES, Park SW, Yun SK

  • KMID: 2451585
  • Korean J Dermatol.
  • 2019 Jun;57(5):243-250.
BACKGROUND: Juvenile xanthogranuloma is a benign, self-limited disorder that usually occurs in infants and young children. Xanthogranuloma is rare in adults, and therefore studies reporting adult xanthogranuloma are limited. OBJECTIVE: We...
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Pigmented Villonodular Synovitis Developing in the Knee of a Rheumatoid Arthritis Patient Mistaken as a Rheumatoid Arthritis Flare-Up

Lee SY, Lee SW, Chung WT

Pigmented villonodular synovitis is a benign tumor arising from synovial fibroblasts or histiocytes. There are diffuse and localized forms: the former involves the entire synovium and the latter consists of...
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Bilateral Frosted Branch Angiitis in Kikuchi-Fujimoto Disease

Kim HM, Choi YJ, Kim ST

PURPOSE: A case of frosted branch angiitis in Kikuchi-Fujimoto disease is reported. CASE SUMMARY: A 33-year-old male complained of a sudden decrease in visual acuity that developed in both eyes 5...
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Erdheim-Chester Disease Presenting as an Anterior Mediastinal Tumor without Skeletal Involvement

Lee K, Kim HR, Roh J, Ok YJ, Jeon BB, Kim YW

Erdheim-Chester disease (ECD) is a form of non–Langerhans cell histiocytosis that most commonly involves the skeletal system. We report an unusual case of ECD presenting as an anterior mediastinal tumor...
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A Case of Erdheim-Chester Disease Developed during Treatment of Leukemia in a Child

Hong JP, Ahn WK, Lim JY, Jung JE, Hahn SM, Han JW, Lyu CJ

Erdheim-Chester disease (ECD) is a rare non-Langerhan's cell histiocytosis disorder characterized by replacement of normal tissue by lipid-laden histiocytes affecting various organs. A few pediatric cases have been reported worldwide....
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The Relation between Tympanostomy Tube Otorrhea and Types of Immune Cells in Middle Ear Effusion in Children with Otitis Media with Effusion

Lim GC, Hyun CL, Kim DY, Choi SH, Song CI

BACKGROUND AND OBJECTIVES: Tympanostomy tube insertion is one of the most common surgical procedures in children. Despite aseptic procedures with prophylactic antibiotic treatment, postoperative otorrhea may be encountered in some...
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Preoperative Cytologic Diagnosis of Warthin-like Variant of Papillary Thyroid Carcinoma

Kim J, Lim BJ, Hong SW, Pyo JY

BACKGROUND: Warthin-like variant of papillary thyroid carcinoma (WLV-PTC) is a relatively rare variant of papillary thyroid carcinoma with favorable prognosis. However, preoperative diagnosis using fine-needle aspiration (FNA) specimens is challenging...
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IgG4-related Ophthalmic Disease Associated with Adult Xanthogranulomatous Disease

Lee S, Chung S, Heo J, Lew H

PURPOSE: To report a case of immunoglobulin G4 (IgG4)-related ophthalmic disease associated with adult xanthogranulomatous disease. CASE SUMMARY: A 38-year-old male with a history of cholecystectomy visited our clinic for bilateral...
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A Case of Intralymphatic Histiocytosis Associated with Breast Cancer

Kim JK, Kim MS, Na CH, Lee YS, Shin BS

  • KMID: 2396217
  • Korean J Dermatol.
  • 2017 Sep;55(8):522-525.
Intralymphatic histiocytosis (IH) is a rare disease with variable and nonspecific clinical features, but with characteristic histopathological findings. Histopathologically, dilated lymphatic vessels containing aggregates of mononuclear cells are observed near...
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Severe Scrub Typhus with Hemophagocytic Lymphohistiocytosis Occurring in Summer

Ahn JS, Noh JH, Kim HR, Jung J, Jo JC, Lim JH, Jun JB

In Korea, scrub typhus usually occurs in October and November. Hemophagocytic lymphohistiocytosis (HLH) is a distinct clinical entity characterized by a high fever, pancytopenia, hepatosplenomegaly, histiocyte proliferation, and hemophagocytosis. We...
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Rosai-Dorfman Disease of 4-Year-Old Girl

Gang JS, Kim YC, Lee YM, Cho J, Suh WS, Park KB

Rosai-Dorfman disease also known as sinus histiocytosis with massive lymphadenopathy is a benign, rare systemic disease characterized by a histiocyte proliferation which presents with lymphadenopathy. We report a case of...
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Erdheim-Chester Disease with Emperipolesis: A Unique Case Involving the Heart

Zhu P, Li N, Yu L, Miranda MN, Wang G, Duan Y

Histiocytosis is an uncommon disease characterized by excessive accumulation of histiocytes. Here, we report a rare case of non-Langerhans-cell histiocytosis in a 51-year-old woman who presented with severe symptoms of...
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A Case of Malignancy-associated Histiocytoid Sweet Syndrome in a Patient with AML

Seo JW, Kim TH, Choi SH, Ha SM, Song KH, Kim KH

  • KMID: 2371085
  • Korean J Dermatol.
  • 2017 Feb;55(2):124-128.
Sweet syndrome is a disorder characterized by painful, erythematous, cutaneous plaques and nodules of rapid onset accompanied by fever, leukocytosis, and neutrophilia. We encountered a case of a recurrent histiocytoid...
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A Case of Inflammatory Pseudotumor Cerebri and Nasal Septum

Jung AR, Hah YM, Kang JW, Lee KH

Inflammatory pseudotumors, which clinically mimic neoplasms, are space-occupying collections of inflammatory cells, histiocytes, and fibroblasts. They are most often found in the orbits and lungs, but rarely in the head...
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Tumor Necrosis Factor Alpha Blocker-Induced Erythrodermic Sarcoidosis in with Juvenile Rheumatoid Arthritis: A Case Report and Review of the Literature

Park SK, Hwang PH, Yun SK, Kim HU, Park J

The development of cutaneous sarcoidosis as a paradoxical adverse event of tumor necrosis factor alpha (TNF-α) blockers has been reported in the literature; however, an erythrodermic form of cutaneous sarcoidosis...
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Palisaded Neutrophilic and Granulomatous Dermatitis Manifested as a LE-nonspecific Skin Lesion

Kim TH, Seo JW, Choi SH, Song KH, Kim KH

  • KMID: 2401256
  • Korean J Dermatol.
  • 2017 Dec;55(10):684-688.
Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a newly defined entity that includes various clinical entities. Histopathologically, this disease is characterized by a granulomatous inflammation with or without leukocytoclastic vasculitis....
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Sclerema Neonatorum in a Full-Term Infant Showing Favorable Prognosis

Park SH, Kim SC

Sclerema neonatorum (SN) is a rare disease characterized by firm, indurated, waxy skin lesions extending throughout the body, sparing the fat-free soles, palms, and genitalia. The prognosis of SN is...
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