Osteoporosis.  2011 Aug;9(2):147-150.

Analysis of the Adherence in Once Yearly Intravenous Zoledronic Acid

• Baek SW
• Lee YS
• Kim JH
• Park YS

Abstract

OBJECTIVES
We investigated drug adherence of once yearly intravenous bisphosphonate in patients with osteoporosis or osteoporotic fractures, and factors that influence their adherence.
MATERIALS AND METHODS
Patients treated with once yearly intravenous bisphosphonate were asked about drug information and drug adherence using questionnaires. Factors related drug adherence were analyzed between non adherence group and adherence group.
RESULTS
65 patients (49.6%) were adherence group, 66 patients (50.3%) were included in non-adherence group. In group 1, were administered mainly due to 'after physicians suggestion' in 22 cases (36.1%) and 'for ease of administration' in 17 cases (27.9%). In group 2, the patients were not readministered mainly due to economic reasons in 21 cases (42%), unconcerning to osteoporosis in 14 cases (28%).
CONCLUSIONS
This study shows 'doctor's suggestion' and 'ease of administration' could enhance drug adherence.

Keyword

Adherence; Bisphosphonate; Osteoporosis; Osteoporotic fracture; Zoledronic acid

MeSH Terms

Diphosphonates
Humans
Imidazoles
Osteoporosis
Osteoporotic Fractures
Surveys and Questionnaires
Diphosphonates
Imidazoles