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One-Year Clinical Outcomes After Diagnosis According to Early Medication Adherence in First-Episode Schizophrenia: A Nationwide, Health Insurance Data-Based Retrospective Cohort Study

Choi W, Joo SW, Ahn S, Choi YJ, Kim SM, Lee J

Objectives: Early pharmacologic intervention is considered necessary for improving the prognosis in patients with first-episode schizophrenia (FES). However, few nationwide population-based studies have focused on early medication adherence. We investigated...
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Persistence with Denosumab in Male Osteoporosis Patients: A Real-World, Non-Interventional Multicenter Study

Jeong C, Lee J, Kim J, Ha J, Jo K, Lim Y, Kim MK, Kwon HS, Sohn TS, Song KH, Kang MI, Baek KH

Background: Persistence with denosumab in male patients has not been adequately investigated, although poor denosumab persistence is associated with a significant risk of rebound vertebral fractures. Methods: We retrospectively evaluated 294...
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Improving Tuberculosis Medication Adherence: The Potential of Integrating Digital Technology and Health Belief Model

Sazali MF, Rahim SSSA, Mohammad AH, Kadir F, Payus AO, Avoi R, Jeffree MS, Omar A, Ibrahim MY, Atil A, Tuah NM, Dapari R, Lansing MG, Rahim AAA, Azhar ZI

Tuberculosis (TB) is a significant public health concern. Globally, TB is among the top 10 and the leading cause of death due to a single infectious agent. Providing standard anti-TB...
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The art of diabetes care: guidelines for a holistic approach to human and social factors

Hashim MJ

A holistic approach to diabetes considers patient preferences, emotional health, living conditions, and other contextual factors, in addition to medication selection. Human and social factors influence treatment adherence and clinical...
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Overcoming Therapeutic Inertia as the Achilles’ Heel for Improving Suboptimal Diabetes Care: An Integrative Review

Chew BH, Mohd-Yusof BN, Lai PSM, Khunti K

The ultimate purpose of diabetes care is achieving the outcomes that patients regard as important throughout the life course. Despite advances in pharmaceuticals, nutraceuticals, psychoeducational programs, information technologies, and digital...
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Video-recording the Eyedrop Instillation Techniques of Glaucoma Patients

Cho YR, Lee TE

Purpose: To analyze eye drop instillation by glaucoma patients using video-recording. Methods: Glaucoma patients who had applied eye drops to both eyes for more than 1 month were enrolled. Patients who...
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Role of home blood pressure monitoring in resistant hypertension

 Kim HM,  Shin J

The definition of resistant hypertension (RHT) has been updated to include failure to achieve target blood pressure (BP) despite treatment with ≥3 antihypertensive drugs, including diuretics, renin-angiotensin system blockers, and...
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Effects of the Insulin Therapy Adherence Program for Patients with Type 2 Diabetes: A Randomized Controlled Trial

Park KM, Son JT

Purpose: This study was conducted to evaluate the effects of the insulin therapy adherence program (INSTA GRAM) for patients with type 2 diabetes mellitus. Methods: This study examined a total...
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Korean Medication Algorithm Project for Bipolar Disorder 2022: Treatment Strategy According to Safety and Tolerability

Park SY, Bahk WM, Woo YS, Jeong JH, Yoon BH, Seo JS, Choo IH, Yang CM, Kim W, Lee JG, Shim SH, Jung MH, Jon DI, Kim MD, Sohn I

Objectives The safety and tolerability of drugs are very important to ensure compliance and efficacy in the treatment of bipolar disorders. An expert opinion survey was conducted on treatment strategies...
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Abnormal Responses in Cognitive Impulsivity Circuits Are Associated with Glycosylated Hemoglobin Trajectories in Type 1 Diabetes Mellitus and Impaired Metabolic Control

Jorge H, Duarte IC, Paiva S, Relvas AP, Castelo-Branco M

Background: Risky health decisions and impulse control profiles may impact on metabolic control in type 1 diabetes mellitus (T1DM). We hypothesize that the neural correlates of cognitive impulsivity and decision-making...
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Improving Medication Adherence in Isolated Patients With Cognitive Impairment Using Automated Telephone Reminders

Kim MJ, Song JY, Jang Jw, Lee SY, Jhoo JH, Byeon GH, Kim Y

Background and Purpose: Medication adherence is essential for effective medical treatment. However, it is challenging for cognitively impaired patients. We investigated whether an automated telephone reminder service improves medication adherence and...
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Effects of medication adherence interventions for older adults with chronic illnesses: a systematic review and meta-analysis

Jeon HO, Chae MO, Kim A

This systematic review and meta-analysis aimed to understand the characteristics of medication adherence interventions for older adults with chronic illnesses, and to investigate the average effect size by combining the...
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Self-Monitoring of Blood Pressure and Feed-back Using APP in TReatment of UnconTrolled Hypertension (SMART-BP): A Randomized Clinical Trial

Choi DJ, Park JJ, Yoon M, Park SJ, Jo SH, Kim EJ, Kim SJ, Lee S

Background and Objectives: Self-monitoring of blood pressure (SMBP) is a reliable method used to assess BP accurately. However, patients do not often know how to respond to the measured BP...
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Adherence to and Dropout from Liraglutide 3.0 mg Obesity Treatment in a Real-World Setting

Ko HJ, Kim JW, Lim S

Background: The factors associated with non-adherence to obesity treatment using liraglutide 3.0 mg in a real-world setting remain elusive. Methods: We performed a secondary data analysis of 769 participants treated with...
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Adherence of bisphosphonate and decreased risk of clinical vertebral fracture in osteoporotic patients: A propensity score matching analysis

Kim S, Chung YS, Lee Y

Objectives: Bisphosphonate is associated with a decreased risk of vertebral fractures due to osteoporosis. However, there are limited studies on how poor compliance with bisphosphonate affects the risk of vertebral...
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Myths and Misconceptions around Antibiotic Resistance: Time to Get Rid of Them

Amábile-Cuevas CF

The antibiotic resistance arena is fraught with myths and misconceptions, leading to wrong strategies to combat it. It is crucial to identify them, discuss them in light of current evidence,...
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The efficacy of denosumab in Korean male patients with osteoporosis

Jeong C, Ha J, Kim J, Lim Y, Kim MK, Kwon HS, Song KH, Kang MI, Baek KH

Background/Aims: Despite the prominence of denosumab as the number one prescribed anti-osteoporosis drug in Korea, the effects of denosumab in male osteoporosis patients were not researched sufficiently. Moreover, concerns on...
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Improvement in Medication Adherence after Pharmacist Intervention Is Associated with Favorable Clinical Outcomes in Patients with Ulcerative Colitis

Kim JS, Geum MJ, Son ES, Yu YM, Cheon JH, Kwon KH

Background/Aims: Although pharmacist intervention for patients with chronic diseases has been shown to improve medication adherence, few studies have evaluated its effects on the objective clinical outcomes. We investigated the...
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Adherence to Antipsychotic Drugs by Medication Possession Ratio for Schizophrenia and Similar Psychotic Disorders in the Republic of Korea: A Retrospective Cohort Study

Cho SJ, Kim J, Lee JY, Sohn JH

Objective: Pharmacotherapy is considered as an essential element in the treatment of psychotic disorders including schizophrenia. Discontinuation of antipsychotic drugs increases medical use and economic burden. Therefore, maintenance of medication...
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Impact of Depression and Social Support on Medication Adherence in Older Adults with Multimorbidity

Kim JE, Park JH, You MA, Seo EJ

Purpose: Medication adherence in older adults with multimorbidity is critical for self-care. The purpose of this cross-sectional study was to identify the factors that influence medication adherence in older adults...
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