Nutr Res Pract.  2007 Dec;1(4):335-340.

Relation of serum total antioxidant status with metabolic risk factors in Korean adults

• Kwak HK
• Yoon S

Abstract

The purpose of the present study was to examine the relation of total antioxidant status (TAS) to metabolic risk factors in Korean adults. Anthropometric measures, blood pressure, serum lipids and fasting glucose were determined in 406 men and women. TAS was measured by using commercially available Randox kit. Serum TAS was significantly positively correlated with body weight (p=0.004), body mass index (BMI) (p=0.033), waist circumference (p=0.017), total cholesterol (p=0.038) and triglyceride (TG) (p<0.001). The mean TAS of hypertriglyceridemic subjects (TG > or =150 mg/dl) was significantly higher than that of subjects whose TG was lower than 150 mg/dl (p=0.001). When central obesity, TG, high density lipoprotein cholesterol, fasting glucose and blood pressure were considered as metabolic risk factors, TAS was shown to be elevated with increased number of metabolic risk factors (p=0.004). The positive association between TAS and a number of metabolic risk factors suggests that increased TAS may not always indicate one's healthier condition. In order to help understand TAS as a marker of total antioxidant capacity in humans with various metabolic conditions, it is needed to clarify the factors affecting TAS in relation to changes in metabolic risk factors.

Keyword

Total antioxidant status; metabolic risk factor; obesity; triglyceride; human

MeSH Terms

Adult*
Blood Pressure
Body Mass Index
Body Weight
Cholesterol
Cholesterol, HDL
Fasting
Female
Glucose
Humans
Male
Obesity
Obesity, Abdominal
Risk Factors*
Triglycerides
Waist Circumference
Cholesterol
Cholesterol, HDL
Glucose

Figure

• 

  Fig. 1 Distribution of the serum TAS according to the number of metabolic risk factors The correlation between the number of metabolic syndrome components and TAS level by Spearman's rank correlation coefficient.

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