Mycobiology.  2006 Dec;34(4):230-235.

Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus

• Lee JW
• Baek SJ
• Bae WC
• Park JM
• Kim YS

Abstract

Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively. Amino acid pattern showed that two extracts contained large amount of aspartic acid and alanine. Two extracts showed characteristic IR absorption pattern for glycosidic bond at 890 cm(-1). PL-H was divided two fractions by gel filtration chromatography and the molecular weights of each fraction were estimated to be about 10 kD and 225 kD, respectively and also PL-A was estimated 10 kD. Two extracts showed strong antitumor, immunomodulating and antioxidant activities, and were compared with commercialized glycopeptide anticancer drugs.

Keyword

Antioxidant; Antitumor; Immunostimulation; Phellinus linteus; Polysaccharide

MeSH Terms

Absorption
Alanine
Alkalies
Aspartic Acid
Chromatography, Gel
Fruit*
Immunization
Molecular Weight
Water
Alanine
Alkalies
Aspartic Acid
Water