Mycobiology.
2010 Mar;38(1):52-57.
Extraction and Characteristics of Anti-obesity Lipase Inhibitor from Phellinus linteus
- Affiliations
-
- 1Chungnam Agricultural Research and Extension Services, Yesan 340-861, Korea.
- 2Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735, Korea. biotech8@pcu.ac.kr
- 3Central Research Institute, Korea Ginseng Corporation, Daejeon 305-805, Korea.
Abstract
- To develop a potent anti-obesity lipase inhibitor from mushroom, the lipase inhibitory activities of various mushroom extracts were determined. Methanol extracts from Phellinus linteus fruiting body exhibited the highest lipase inhibitory activity (72.8%). The inhibitor was maximally extracted by treatment of a P. linteus fruiting body with 80% methanol at 40degrees C for 24 hr. After partial purification by systematic solvent extraction, the inhibitor was stable in the range of 40~80degrees C and pH 2.0~9.0. In addition to lipase inhibitory activity, the inhibitor showed 59.4% of superoxide dismutase-like activity and 56.3% of acetylcholinesterase inhibitory activity.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Optimal Extraction Conditions of Anti-obesity Lipase Inhibitor from Phellinus linteus and Nutritional Characteristics of the Extracts
- PCR-Based Sensitive Detection of Wood-Decaying Fungus Phellinus linteus by Specific Primer from rDNA ITS Regions
- Artificial Cultivation Characteristics and Bioactive Effects of Novel Tropicoporus linteus (Syn. Phellinus linteus) Strains HN00K9 and HN6036 in Korea
- Development of Species-specific Primers for Rapid Detection of Phellinus linteus and P. baumii
- Quality Characteristics of Yanggaeng Supplemented with Sanghwang Mushroom (Phellinus linteus) Mycelia
