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Bisphosphonate: An Invaluable Medication or Abandoned Acid?

Chung H, Lee JW, Um JW, Sohn HS

Over the last two decades, bisphosphonate has widely been applied in the treatment of osteoporosis. We reviewed the various adverse effects, current trials involving diverse bone metabolic diseases, and the future direction...
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Mandibular skeletal posterior anatomic limit for molar distalization in patients with Class III malocclusion with different vertical facial patterns

Kim SH, Cha KS, Lee JW, Lee SM

Objective: The aim of this study was to compare the differences in mandibular posterior anatomic limit (MPAL) distances stratified by vertical patterns in patients with skeletal Class III malocclusion by...
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Downregulation of MicroRNA-495 Alleviates IL-1β Responses among Chondrocytes by Preventing SOX9 Reduction

Joung S, Yoon DS, Cho S, Ko EA, Lee KM, Park KH, Lee JW, Kim SH

Purpose: Our previous work demonstrated that miRNA-495 targets SOX9 to inhibit chondrogenesis of mesenchymal stem cells. In this study, we aimed to investigate whether miRNA-495-mediated SOX9 regulation could be a novel...
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Association between Electronic Cigarettes, Conventional Cigarettes, and Dual Use and Inflammation and Oxidative Stress: The Seventh Korean National Health and Nutrition Examination Survey 2016–2018

Seo Hj, Kim Jh, Kim Sa, Shin Wy, Lee Jw, Cho SH

Background: The rate of e-cigarette use is increasing due to the perception that there is a smoking cessation effect and that there is relatively low harm; most users use e-cigarettes in...
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Comparison of Clinical Outcomes and Complications of Primary and Revision Surgery Using a Combined Anterior and Posterior Approach in Patients with Adult Spinal Deformity and Sagittal Imbalance

Kim WJ, Shin HM, Song DG, Lee JW, Park KY, Chang SH, Bae JH, Choy WS

Background: The purpose of this study was to compare clinical outcomes and complications of primary and revision surgery in patients with adult spinal deformity (ASD) accompanied by sagittal imbalance. Revision...
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Comparative Surgical Outcomes of Prosthetic and Native Valve Endocarditis

Pyo WK, Kim HJ, Kim JB, Jung SH, Choo SJ, Chung CH, Lee JW

Background and Objectives: As a consequence of a growing number of patients undergoing prosthetic heart valve replacement, the incidence of prosthetic valve endocarditis (PVE) has increased. The study aims to...
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Pre-transplant Dementia is Associated with Poor Survival After Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study with Propensity Score Matched Control

Wang SM, Park SS, Park SH, Kim NY, Kang DW, Na HR, Bae YY, Lee JW, Han S, Lim HK

Objective: No previous study examined impact of dementia in the outcome of allogeneic hematopoietic stem cell transplantation (HSCT). We aimed to investigate overall survival (OS) of patients with dementia after...
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Characteristic Clinical Features of Korean Atopic Dermatitis Patients with Interleukin-17 Receptor A Gene Mutation

Lee JW, Yu K, Lee H, Choi EH

  • KMID: 2516142
  • Korean J Dermatol.
  • 2021 May;59(4):290-295.
Background: Th17 cytokines such as interleukin-17 and interleukin-22 are expressed in atopic dermatitis lesions. Previous studies have reported increased levels of interleukin-17A, -17E, and -17F in patients with atopic dermatitis.As...
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Sporadic Intradural Extramedullary Hemangioblastoma Not Associated with von Hippel-Lindau Syndrome: A Case Report and Literature Review

Um MK, Lee E, Lee JW, Lee KS, Kang Y, Ahn JM, Kang HS

Hemangioblastomas are low-grade, highly vascular tumors that are usually associated with von Hippel-Lindau syndrome. Hemangioblastomas most commonly occur in the cerebellum, and intradural extramedullary hemangioblastoma of the cauda equina is...
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Endovascular Treatment of a Systemic-to-Pulmonary Artery Fistula: A Case Report

Lee E, Shim DJ, Kim D, Lee JW

Systemic-to-pulmonary artery fistulas are rare. This condition may be congenital, post-traumatic, or post-inflammatory and can cause infection, hemorrhage, or pulmonary hypertension. Here, we report a case of an intercostal-to-pulmonary artery...
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Open Partial Nephrectomy vs. Robotassisted Partial Nephrectomy for a Renal Tumor Larger than 4 cm: a Propensity Score Matching Analysis

Lee S, Ryu H, Lee JW

Background: To compare open partial nephrectomy (OPN) and robot-assisted partial nephrectomy (RAPN) in the management of renal tumors larger than 4 cm. Methods: Clinical records of 220 patients who underwent OPN...
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Conditioning with 10 Gy Total Body Irradiation, Cyclophosphamide, and Fludarabine without ATG Is Associated with Improved Outcome of Cord Blood Transplantation in Children with Acute Leukemia

Cho HW, Ju HY, Hyun JK, Lee Jw, Sung KW, Koo HH, Lim DH, Yoo KH

Background: The optimal conditioning regimen in cord blood transplantation (CBT) needs to be determined. This study aimed to identify the impact of conditioning regimen on the outcome of CBT in...
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Unusual Case of Vesicoureteral Reflux and Chronic Kidney Disease in a 10-Year-old Boy with Asymptomatic Bacteriuria

Choi YD, Lee JH, Lee JW

Primary vesicoureteral reflux is a common genetically determined condition that is associated with varying degrees of renal scarring and represents one of the main causes of chronic kidney disease in...
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Multicenter, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of a Controlled-release, Once-daily UIC201609/UIC201610 Combination Therapy for Functional Dyspepsia: Preliminary Study

Lee JW, Youn YH, Choi SC, Lee KJ, Kim N

Background/Aims: Functional dyspepsia is a disease involving a range of upper gastrointestinal symptoms derived from various pathophysiologies. Tablets containing a combination of rabeprazole and controlled-release (CR) mosapride were recently developed. To...
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Recent Trends in Opioid Prescription in Cancer Patients in Korea

Yoon J, Kim HS, Lee JW, Kim J, Kang HT

Background: This study aimed to estimate the trends in opioid prescriptions for pain control in patients with and without cancer between 2002 and 2015. Methods: This retrospective study was based on...
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Clinical Course of Amyotrophic Lateral Sclerosis according to Initial Symptoms: An Analysis of 500 Cases

Lee JW, Kang SW, Choi WA

Purpose: One obstacle in early diagnosis of amyotrophic lateral sclerosis (ALS) is its vague initial presentation, which is generally classified into limb- and bulbar-dominant types and may be mistaken for...
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Association between Second-hand Smoke Exposure and Urinary NNAL Level in Korean Adolescents

You HS, Lee Jw, Kim Ys, Kim Y, Lee HC, Hwang JY, Yang W, Kang HT

Background: The 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is a metabolite of tobacco-specific lung carcinogen that can be found in both smokers and non-smokers. Particularly, NNAL levels of children with a history of exposure to...
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Early Trauma and Relationships among Recent Stress, Depressive Symptoms, Anxiety Symptoms, and Suicidal Ideation in Korean Women

Park CHK, Lee JW, Moon J, Jeon DW, Lee SY, Shim SH, Kim SG, Lee J, Paik JW, Cho SJ, Kim MH, You S, Jeon HJ, Rhee SJ, Kim MJ, Kim J, Ahn YM

Background: Evidence continues to accumulate that the presence or absence of early trauma (ET) implies unique characteristics in the relationships between suicidal ideation and its risk factors. We examined the...
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Quantification of Thioguanine in DNA Using Liquid Chromatography-Tandem Mass Spectrometry for Routine Thiopurine Drug Monitoring in Patients With Pediatric Acute Lymphoblastic Leukemia

Choi R, Chun MR, Park J, Lee JW, Ju HY, Cho HW, Hyun JK, Koo HH, Yi ES, Lee SY

Background: We developed an assay to measure DNA-incorporated 6-thioguanine (DNATG) and validated its clinical applicability in Korean pediatric patients with acute lymphoblastic leukemia (ALL) in order to improve individualized thiopurine...
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Sonographic Appearance of Steatocystoma: An Analysis of 14 Pathologically Confirmed Lesions

Yoon H, Kang Y, Park H, Ahn JM, Lee E, Lee JW, Kang HS

Purpose To evaluate the ultrasonographic characteristics of steatocystomas focusing on the features that aid in differentiating them from epidermal inclusion cysts and lipomas. Materials and Methods The ultrasonographic findings of 14...
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