Korean J Nephrol.
2009 Nov;28(6):658-662.
A Case of Chronic Renal Failure in a Polydipsic Schizophrenic Patient caused by Chronic Anticholinergic Therapy
- Affiliations
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- 1Department of Internal Medicine, Sam Anyang Hospital, Anyang, Gyeonggi-do, Korea. thekidney@korea.com
Abstract
- Anticholinergic drugs block muscarinic receptors at the detrusor muscle of the bladder. It can cause urinary retention by contracting the bladder neck. Cases of hydronephrosis, bladder dilatation as a result of polydipsia while taking anticholinergic drugs have been reported, but very few cases of chronic renal failure can be found. We report a case of a polydipsic schizophrenic patient who, after taking anticholinergic drugs as antipsychotic drugs to treat his schizophrenia for a long time, presented with chronic renal failure due to functional obstructive uropathy in the absence of demonstrable anatomic causes of obstruction.
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