- Distribution of the muscarinic receptors and characterization in the brain of wistar rats and spontaneously hypertensive rats(SHR strain) by digital autoradiography
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Sohn I, Lee MC, Koh CS
- KMID: 1685934
- Korean J Nucl Med.
- 1993 May;27(1):28-34.
No abstract available. -
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- Muscarinic Receptors Distributed in the Lower Urinary Tract
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Kim DY
- KMID: 2331536
- J Korean Continence Soc.
- 2009 Jun;13(1):1-6.
Acetylcholine (Ach) acting on the muscarinic receptors is the major stimulus for the detrusor inducing contraction if the bladder is distended and the bladder volume is at the threshold. There... -
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- Muscarinic receptor subtype controlling the carbachol-induced muscle contraction in guinea pig gastric antrum
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Rhee JC, Uhm DY, Kang TM
- KMID: 1982596
- Korean J Physiol Pharmacol.
- 2000 Apr;4(2):105-111.
Stimulation of muscarinic receptors by carbachol (CCh) in the circular smooth muscle of the guinea pig gastric antrum causes muscle contraction. In the present study, muscarinic receptor subtype controlling the muscle contraction in... -
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- Effects of Halothane, Enflurane or Isoflurane on the m1 or m3 Muscarinic Receptor Expressed in Xenopus Oocytes
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Do SH
- KMID: 2091577
- Korean J Anesthesiol.
- 2000 Dec;39(6):854-859.
- doi: 10.4097/kjae.2000.39.6.854
BACKGROUND: Muscarinic receptors are distributed abundantly in the central nervous system and peripheral visceral organs, and have a close relationship with anesthesia. We investigated the effects of halothane, enflurane... -
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- Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding
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Yamada S, Kuraoka S, Osano A, Ito Y
- KMID: 2232961
- Int Neurourol J.
- 2012 Sep;16(3):107-115.
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed. Transdermal administration of oxybutynin... -
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- Primary role of posterior hypothalamic cholinergic receptors in central regulation of blood pressure and heart rate in rats
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Kim SY, Sung KW, Koh HC, Lee SB
- KMID: 2285181
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):639-645.
The purpose of the present study is to determine the role of muscarinic cholinergic receptors of posterior hypothalamus in the central blood pressure regulation when respiration is controlled. In anesthetized and artificially ventilated... -
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- Enhanced coupling of M-1 muscarinic receptors to activation of phospholipase C upon mutation of a transposed amino acid triplet repeat
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Lee SY, Sung KW, Kim ON, Lee SB
- KMID: 2285154
- Korean J Physiol Pharmacol.
- 1997 Feb;1(1):19-25.
The C-terminus ends of the second putative transmembrane domains of both M-1 and M-2 Muscarinic receptors contain a triplet of amino acid residues consisting of leucine (L), tyrosine (Y) and threonine (T). This... -
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- Function of the neuronal M2 muscarinic receptor in asthmatic patients
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Kwon YH, Lee SY, Bak SM, Lee SH, Shin C, Cho JY, Shim JJ, Kang KH, Yoo SH, In KH
- KMID: 2160322
- Tuberc Respir Dis.
- 2000 Oct;49(4):486-494.
- doi: 10.4046/trd.2000.49.4.486
BACKGROUND: The dominant innervation of airway smooth muscle is parasympathetic fibers which are carried in the vagus nerve. Activation of these cholinergic nerves releases acetylcholine which binds to M3 muscarinic... -
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- Characteristics of Muscarinic Receptor Subtypes in Guinea Pig Gallbladder Smooth Muscle
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Lee JK, Rhee PL, Kang TM, Kim JJ, Koh KC, Paik SW, Rhee JC
- KMID: 1891138
- Korean J Gastroenterol.
- 1997 Jul;30(1):90-97.
BACKGROUND AND AIMS: Acetylcholine (Ach) is the most irnportant rnediator in vagal-induced and cholecystokinin-induced gallbladder contraction. There are several rnuscarinic receptor subtypes characterized by pharmacologic study. The majority of smooth... -
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- The Effect of Unilateral Orbital Enucleation on Acetylcholine and Muscarinic Receptors in Visual Pathway, and Physical Activity of Rats
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Kim YH, Pae YS, Cho BC
- KMID: 2123358
- J Korean Ophthalmol Soc.
- 1995 May;36(5):855-867.
Acetylcholine is one of the major neurotransmitters in visual system of rats. Cholinergic, serotonergic and gamma-aminobutyric acid(GABA) ergic projections are known as modulators of visual processing. The purpose of this... -
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- The Effects of Estrogen on Detrusor Contraction and the Expression of Muscarinic Receptors in Ovariectomized Rats
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Chung HY, Chang JS, Kim SH, Song KH, Jang YS, Han DS
- KMID: 2311915
- Korean J Urol.
- 2008 Dec;49(12):1105-1111.
PURPOSE: The purpose of this study was to evaluate the effects of estrogen on detrusor contraction and the expression of muscarinic receptors in ovariectomized rats. MATERIALS AND METHODS: 24 Sprague-Dawley female... -
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- Expression of Muscarinic Receptors and the Effect of Tiotropium Bromide in Aged Mouse Model of Chronic Asthma
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Kang JY, Kim IK, Hur J, Kim SC, Lee SY, Kwon SS, Kim YK
- KMID: 2441732
- Tuberc Respir Dis.
- 2019 Jan;82(1):71-80.
- doi: 10.4046/trd.2018.0049
BACKGROUND: Efficacy and safety of tiotropium bromide, a muscarinic receptor antagonist, in treatment of asthma have been reported. However, its effect on airway remodeling in chronic asthma of the elderly... -
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- The Effect of Muscarinic Receptor Subtype Antagonists on Detrusor Overactivity Induced by Bladder Outlet Obstruction in Rats
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Kim SJ, Hwang TK, Kim JC
- KMID: 2139737
- Korean J Urol.
- 2007 Oct;48(10):1044-1049.
- doi: 10.4111/kju.2007.48.10.1044
PURPOSE: We studied the role of the muscarinic receptor subtype on the urothelium and detrusor activity in rats with detrusor overactivity induced by bladder outlet obstruction(BOO). MATERIALS AND METHODS: Forty Sprague-Dawley... -
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- Effects of Vecuronium and Pancuronium on the Tension of the Smooth Muscle in the Rat Trachea
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Kim SS, Son YS, Kim YH, Yoon SH, Lee JU, Kim HJ
- KMID: 2236854
- Korean J Anesthesiol.
- 1999 Jul;37(1):139-143.
- doi: 10.4097/kjae.1999.37.1.139
BACKGROUND: Vecuronium and Pancuronium have been proven to be associated with nicotinic receptor of skeletal muscle. Generally, nondepolarizing muscle relaxant is associated with contraction of smooth tracheal muscle, but there... -
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- Antidote for organophosphate insecticide poisoning: atropine and pralidoxime
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Chung SP, Roh HK
- KMID: 1783720
- J Korean Med Assoc.
- 2013 Dec;56(12):1057-1066.
- doi: 10.5124/jkma.2013.56.12.1057
Acute organophosphate (OP) poisoning produces cholinergic symptoms resulting from the inhibition of cholinesterase, and the overstimulation of muscarinic and nicotinic receptors in the synapses. The dominant clinical features of acute... -
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- Additive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test
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Park CH, Kim PN, Lee SH, Yoon MH
- KMID: 1798229
- Korean J Anesthesiol.
- 2013 Feb;64(2):152-160.
- doi: 10.4097/kjae.2013.64.2.152
BACKGROUND: The authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the... -
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- The role of spinal adrenergic receptors on the antinociception of ginsenosides in a rat postoperative pain model
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Kim IJ, Park CH, Lee SH, Yoon MH
- KMID: 1828069
- Korean J Anesthesiol.
- 2013 Jul;65(1):55-60.
- doi: 10.4097/kjae.2013.65.1.55
BACKGROUND: The effect of spinal adrenergic and cholinergic receptors on the anti-nociceptive effect of intrathecal ginsenosides was determined in a rat postoperative pain model. METHODS: Catheters were placed into the intrathecal... -
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- Local Effects of Antimuscarinics on Muscarinic Receptors in Bladder Sensory Nerves
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Park MS, Cho SW, Han KH, Lee SC, Kim WJ, Kim YT
- KMID: 2330522
- J Korean Continence Soc.
- 2006 Jun;10(1):17-22.
PURPOSE: To investigate the role of muscarinic receptors in bladder sensory mechanism. MATERIALS AND METHODS: Normal adult volunteers collected voided urine after taking five days of trospium(20 mg bid), tolterodine LA(4... -
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- The Antiallodynic Effect of Edrophonium and Neostigmine in a Neuropathic Pain Model
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Hwang JH, Ham KD, Lee DM
- KMID: 2240181
- Korean J Anesthesiol.
- 1997 Jul;33(1):33-40.
- doi: 10.4097/kjae.1997.33.1.33
BACKGROUND: Peripheral nerve injury may produce a syndrome consisting of spontaneous pain, allodynia and hyperpathia. Cholinesterase inhibitors are known to have an antinociceptive effect in hot plate and tail flick... -
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- Effect of Spinal Adrenergic and Cholinergic Antagonists for Antinociception of Intrathecal Gabapentin
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Yoon MH, Chung SS, Kim HS
- KMID: 2091695
- Korean J Anesthesiol.
- 2002 May;42(5):677-684.
- doi: 10.4097/kjae.2002.42.5.677
BACKGROUND: Intrathecal gabapentin is effective on nociceptive states evoked by tissue injury. In addition, gabapentin interacts synergistically with clonidine at the spinal level, suggesting that a mechanism of gabapentin... -
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