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Systematic review of literature and analysis of big data from the National Health Insurance System on primary immunodeficiencies in Korea

Son S, Kang JM, Hahn Y, Ahn K, Kim YJ

There are very scant data on the epidemiology of primary immunodeficiency diseases (PIDs) in Korea. Here we attempted to estimate the PID epidemiology and disease burden in Korea. A systematic...
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Continued Upward Trend in Non-Tuberculous Mycobacteria Isolation over 13 Years in a Tertiary Care Hospital in Korea

Ahn K, Kim YK, Hwang GY, Cho H, Uh Y

Purpose: Despite decreased prevalence of tuberculosis, the incidence of the diseases associated with nontuberculous mycobacteria (NTM) has been increasing in South Korea and around the world. The present retrospective study...
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Three cases of oral immunotherapy for IgE-mediated egg allergy

Kim I, Lee BR, Kyung Y, Jung M, Yang HK, Kim M, Lee JY, Kim J, Ahn K, Jeong HI

Food allergy is an immune-mediated adverse reaction that occurs mainly by food ingestion. Some children with food allergies manifest fatal symptoms like anaphylaxis. Oral immunotherapy (OIT) may offer an effective...
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Imbalance of Gut Streptococcus, Clostridium, and Akkermansia Determines the Natural Course of Atopic Dermatitis in Infant

Park YM, Lee SY, Kang MJ, Kim BS, Lee MJ, Jung SS, Yoon JS, Cho HJ, Lee E, Yang SI, Seo JH, Kim HB, Suh DI, Shin YH, Kim KW, Ahn K, Hong SJ

PURPOSE: The roles of gut microbiota on the natural course of atopic dermatitis (AD) are not yet fully understood. We investigated whether the composition and function of gut microbiota and...
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Flow Cytometry for the Diagnosis of Primary Immunodeficiency Diseases: A Single Center Experience

Kwon WK, Choi S, Kim HJ, Huh HJ, Kang JM, Kim YJ, Yoo KH, Ahn K, Cho HK, Peck KR, Jang JH, Ki CS, Kang ES

PURPOSE: While there is an urgent need for diagnosis and therapeutic intervention in patients with primary immunodeficiency diseases (PIDs), current genetic tests have drawbacks. We retrospectively reviewed the usefulness of...
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The Role of Nerve Conduction Comparison Test and Ultrasonography in Diagnosing Carpal Tunnel Syndrome

Ahn K, Youn M, Park JM, Lee JJ, Lee Ww, Kang K, Kim BK, Kwon O

Background: The median-to-ulnar comparison test (MUCT), and increasingly, ultrasonography (US) are considered as complementary to and more sensitive than median nerve conduction study (NCS) in diagnosing carpal tunnel syndrome (CTS). Methods:...
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Reversible Vasoconstriction of Intracranial Artery in Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes

Ahn K, Kim H, Park JM, Kwon O, Lee JJ, Kim BK, Kang K, Lee WW

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Interactions Between Atopic Dermatitis and Staphylococcus aureus Infection: Clinical Implications

Kim J, Kim BE, Ahn K, Leung DY

Staphylococcus aureus commonly colonizes the skin of atopic dermatitis (AD) patients and contributes to the development and exacerbation of AD. Multiple factors are associated with colonization of AD skin by...
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A case of FLNA gene mutation with respiratory insufficiency and periventricular heterotopia

Park H, Park MS, Ki CS, Cho J, Lee J, Kim J, Ahn K

Filamin A is an actin-binding protein and, in humans, is encoded by FLNA gene in the long arm of X chromosome. Filamin A plays a role in the formation of...
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Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli

Ahn K, Hwang GY, Kim YK, Kim HY, Jeong HR, Hong JS, Uh Y

Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or...
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Higher Fatality for Severe Fever with Thrombocytopenia Syndrome Complicated by Hemophagocytic Lymphohistiocytosis

Jung IY, Ahn K, Kim J, Choi JY, Kim HY, Uh Y, Kim YK

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious zoonosis caused by the SFTS virus. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome associated with excessive immune activation. Cytokine storms...
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Different expression of GSK3β and pS9GSK3β depending on phenotype of cervical cancer: possible association of GSK3β with squamous cell carcinoma and pS9GSK3β with adenocarcinoma

Ahn K, Kweon S, Kim DW, Lee H

OBJECTIVE: This study aimed to analyze the expression pattern of glycogen synthase kinase 3β (GSK3β) and its phosphorylated forms, GSK3β phosphorylated at Ser9 (pS9GSK3β), and GSK3β phosphorylated at Tyr216 (pY216GSK3β),...
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Leukocyte Telomere Length Reflects Prenatal Stress Exposure, But Does Not Predict Atopic Dermatitis Development at 1 Year

Suh DI, Kang MJ, Park YM, Lee JK, Lee SY, Sheen YH, Kim KW, Ahn K, Won HS, Lee MY, Choi SJ, Kwon JY, Park HJ, Jun JK, Hong SJ, Koh YY

PURPOSE: Prenatal maternal stress affects offspring's atopic dermatitis (AD) development, which is thought to be mediated by the oxidative stress. We aimed to evaluate the difference in leukocyte telomere length...
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The current status and issue of food allergen labeling in Korea

Jeon YH, Kim HH, Park YM, Jang GC, Kim HY, Yum HY, Kim J, Ahn K, Min TK, Pyun BY, Lee S, Kim KW, Kim YH, Lee J, Lee SY, Kim WK, Song TW, Kim JH, Lee YJ, The Korean Academy of Pediatric Allergy and Respiratory Diseases, Food Allergy and Atopic Dermatitis Study Group

With increasing need to prevent serious food allergy reactions, Korean food allergen labeling regulation has been revised repeatedly. This paper aims to summarize current statuses of food allergen labeling in...
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Infantile Anaphylaxis in Korea: a Multicenter Retrospective Case Study

Jeon YH, Lee S, Ahn K, Lee SY, Kim KW, Kim HH, Kim JH, Yum HY, Kim WK, Park YM, Song TW, Kim J, Lee YJ, Jang GC, Jeong K, Kim YH, Min TK, Pyun BY, on behalf of the Food Allergy and Atopic Dermatitis (FAAD) Study Group in the Korean Academy of Pediatric Allergy and Respiratory Disease

BACKGROUND: Anaphylaxis is increasing in young children. The aim of the present study was to analyze the clinical characteristics of anaphylaxis in Korean infants, with a focus on food triggers. METHODS:...
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Prenatal Exposure to Lead and Chromium is Associated with IL-13 Levels in Umbilical Cord Blood and Severity of Atopic Dermatitis: COCOA Study

Kim J, Kim S, Woo SY, Chung JY, Hong YS, Oh SY, Choi SJ, Oh SY, Kim KW, Shin YH, Won HS, Lee KJ, Kim SH, Kwon JY, Lee SH, Hong SJ, Ahn K

There have been few studies investigating the association between atopic dermatitis (AD) and prenatal exposure to heavy metals. We aimed to evaluate whether prenatal exposure to heavy metals is associated...
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Comparison of radiation exposure by area before and after emergency center remodeling

Ahn K, Lee SB, Kim DH, Kim T, Kang C, Lee SH, Jeong JH, Kim SC, Park YJ, Lim D

OBJECTIVE: Radiation is used extensively in emergency centers. Computed tomography and X-ray imaging are used frequently. Portable X-rays, in particular, cause a significant amount of indirect radiation exposure to medical...
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The risk of preschool asthma at 2–4 years is not associated with leukocyte telomere length at birth or at 1 year of age

Suh DI, Kang MJ, Park YM, Lee JK, Lee SY, Sheen YH, Kim KW, Ahn K, Hong SJ

BACKGROUND: Exposure to prenatal stress is associated with offspring allergic-disease development, and oxidative stress may mediate this relationship. OBJECTIVE: We aimed to evaluate whether leukocyte telomere length (LTL) shortening, a marker...
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The past, present, and future of the research on food allergy in Korean children

Ahn K

Food allergy is an immune-mediated adverse reaction that occurs mainly by consumption of food. Some of the children with food allergies have mild symptoms like urticaria and pruritus, while others...
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Synergistic Anti-Cancer Effects of AKT and SRC Inhibition in Human Pancreatic Cancer Cells

Ahn K, O YM, Ji YG, Cho HJ, Lee DH

PURPOSE: To investigate the effect of combined inhibition of protein kinase B (AKT) and SRC on the growth and metastatic potential of human pancreatic cancer cells. MATERIALS AND METHODS: AKT and...
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