Korean J Med.  2008 Apr;74(4):451-456.

A case of acute eosinophilic fulminant myocarditis associated with paragonimiasis

Affiliations
  • 1Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea. dgpark@hallym.or.kr

Abstract

Fulminant myocarditis is characterized by critical illness at presentation. However, if affected patients recover with pharmacologic therapy and mechanical circulatory support, they may have a better long-term prognosis than patients with other forms of myocarditis. A 31-year-old man was admitted due to chest pain associated with dyspnea. Electrocardiogram showed ST-segment elevation in all leads except for aVR and aVL. Non-sustained ventricular tachycardia developed 12 hours after admission. The echocardiography showed diffuse hypokinesia, concentric edematous thickening of the left ventricular wall, and pericardial effusion. Serum cardiac enzymes and absolute eosinophil count were elevated. Since the ELISA (Enzyme-Linked Immunosorbent Assay) against Paragonimus westermani was positive, the patient was treated with praziquantel for 2 days. Eosinophil count normalized after 10 days, with conversion to negativity on ELISA after 4 weeks. We concluded that his myocarditis was probably caused by allergic reaction secondary to Paragonimus westermani infection.

Keyword

Myocarditis; Eosinophilia; Paragonimiasis

MeSH Terms

Adult
Chest Pain
Critical Illness
Dyspnea
Echocardiography
Electrocardiography
Enzyme-Linked Immunosorbent Assay
Eosinophilia
Eosinophils
Humans
Hypersensitivity
Hypokinesia
Myocarditis
Paragonimiasis
Paragonimus westermani
Pericardial Effusion
Praziquantel
Prognosis
Tachycardia, Ventricular
Praziquantel
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