Korean J Gastrointest Endosc.  2007 Jan;34(1):28-32.

A Case of Esophageal T-cell Lymphoma Presenting as Multiple Discrete Ulcers on a Background of Normal Mucosa

  • 1Department of Internal Medicine, Inje University College of Medicine, Paik Hospital, Busan, Korea.
  • 2Department of Internal Medicine, Adventist Hospital, Busan, Korea. lesabo@kornet.net


Gastrointestinal involvement by a lymphoma occurs in 20% of patients with a lymphoma and frequently involves the stomach, small bowel or colon, but rarely involves the esophagus. Esophageal lymphomas are usually secondary to an adjacent lymph node invasion or the contiguous spread from a gastric lymphoma. Primary involvement of the esophagus by a lymphoma is quite rare. Primary versus secondary esophageal involvement by a lymphoma is difficult to determine. The radiological features of esophageal lymphomas may manifest nodules of various sizes, enlarged folds, polypoid mass, ulceration, stenosis, varicoid appearance, and aneurysmal dilatation. The presentation of multiple discrete ulcers in the esophagus on the background of the normal mucosa is most unusual. We describe a case of an esophageal T-cell lymphoma with multiple discrete ulcers on the background of the normal mucosa. The patient was treated with chemotherapy. After chemotherapy, the endoscopic findings of the esophagus showed a normal esophageal mucosa. We report this case with a review of the relevant literature.


Malignant lymphoma; Esophagus; Ulcer
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