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Lovastatin derivative dehydrolovastatin ameliorates ulcerative colitis in mice by suppressing NF-κB and inflammatory cytokine expression

Zhang X, Deng QH, Deng JH, Wang SJ, Chen Q

Ulcerative colitis (UC) is associated with intestinal immune imbalance and inflammatory response. Because dehydrolovastatin (DLVT), a derivative of lovastatin, has been recently shown to inhibit inflammation and relieve immune arthritis...
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The Interrater Agreement for the Assessment of Pressure Ulcer Risk Using the Braden Scale and the Classification of Pressure Ulcers by Nurses in A Medium-Sized Hospital

Na HJ, Yoo SH, Kwon YR, Ahn MJ

PURPOSE: This methodological study was conducted to evaluate the interrater agreement in pressure ulcer risk assessment using the Braden scale, and in pressure ulcer classification, by nurses in a medium-sized...
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Corneal Collagen Cross-linking for Corneal Ulcer from Moraxella Group

Woo SE, Lee SH

PURPOSE: To report a case of corneal collagen cross-linking for corneal ulcer caused by the Moraxella group. CASE SUMMARY: A 77-year-old male had decreased visual acuity for several days in his...
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An Atypical Extraintestinal Manifestation in a Child with Ulcerative Colitis: Cutaneous Leukocytoclastic Vasculitis

Oh SJ, Choi Y, Kim CR, Park JH, Lee JH, Lee DY

No abstract available.
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Effect of Sodium Cromoglycate on Acetic Acid-induced Ulcerative Colitis in Mice

Ghafouri Z, Seyyedian , Nikbakht J, Kouhsari E, Bayat S, Zargar H, Houshmand

BACKGROUND/AIMS: Ulcerative colitis (UC) is a type of inflammatory bowel disease that mainly involves the colon. Thus far, glucocorticoids and amino-salicylate have been the main treatment. METHODS: To assess drugs with...
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Refractory Digital Ulcers Treated by Botulinum Toxin and Endothelin Receptor-1 Antagonist in Anti-MDA5-Antibody-Positive Dermatomyositis

Min HK, Kim HR, Lee SH, Park SH, Oh J, Choi K

No abstract available.
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Comparison of Real-World Outcomes of Infliximab versus Adalimumab in Biologic-Naïve Korean Patients with Ulcerative Colitis: A Population-Based Study

Han M, Jung YS, Cheon JH, Park S

PURPOSE: Data on the comparative effectiveness of infliximab (IFX) or adalimumab (ADA) in patients with ulcerative colitis (UC) are extremely limited, especially in the Asian population. We compared clinically important...
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A case of gastroduodenal ulcer complicating Kawasaki disease

Sohn H, Kim K, Koh H, Kim S

Kawasaki disease (KD) is a systemic vasculitis associated with various clinical manifestations and complications, such as gastrointestinal abnormalities. We report a 3-year-old boy who presented with hematemesis and diffuse gastroduodenal...
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Gastric Ulcers with Cytomegalovirus Infection in an Immunocompetent Patient

Kim TO, Shim KN, Kim SY, Lim JY, Choe AR, Tae CH, Moon CM, Kim SE, Jung HK, Jung SA

Cases of cytomegalovirus (CMV) infection are rare, and this infection is commonly asymptomatic in immunocompetent patients. Here, we report a pathologically proven case of CMV infection in gastric ulcers in...
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Relapsed Leprosy with Multiple Ulcerative Skin Lesions: A Case Report

Jeong HH, Hong SG, Park JM, Kim JP, Heo EP, Go JW

Leprosy is a chronic infectious and granulomatous disease caused by Mycobacterium leprae. It is treated with a multidrug therapy (MDT), which is consisted of dapsone, rifampicin, and clofazimine. However, there...
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Treatment Using a Single-Lobed Rotation Flap in Diabetic Forefoot Ulceration: Five Case Reports

Kim JB, Lee BJ, Kim CU, Jung D

Diabetic foot ulcers can progress to the point where amputation is needed, and so these ulcers require active treatment. Skin grafts or flaps can be performed for coverage of this...
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Delayed Duodenal Perforation of an Endoscopic Mucosal Resection-Induced Ulcer due to a Foreign Body

Gweon TG, Huh CW, Kim BW

No abstract available.
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Polypharmacy is a risk factor for disease flare in adult patients with ulcerative colitis: a retrospective cohort study

Wang J, Nakamura T, Tuskey AG, Behm BW

BACKGROUND/AIMS: Polypharmacy is a common clinical problem with chronic diseases that can be associated with adverse patient outcomes. The present study aimed to determine the prevalence and patient-specific characteristics associated...
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Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan

Yanagi T, Ushijima K, Koga H, Tomomasa T, Tajiri H, Kunisaki R, Isihige T, Yamada H, Arai K, Yoden A, Aomatsu T, Nagata S, Uchida K, Ohtsuka Y, Shimizu T

BACKGROUND/AIMS: Tacrolimus is effective for refractory ulcerative colitis in adults, while data for children is sparse. We aimed to evaluate the effectiveness and safety of tacrolimus for induction and maintenance...
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Tacrolimus in pediatric ulcerative colitis: does it have a role?

Kim S

No abstract available.
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Development and Evaluation of Electronic Health Record Data-Driven Predictive Models for Pressure Ulcers

Park SK, Park HA, Hwang H

PURPOSE: The purpose of this study was to develop predictive models for pressure ulcer incidence using electronic health record (EHR) data and to compare their predictive validity performance indicators with...
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A Case of Anti-Le(bH) Antibody Identified in a Patient with Ulcerative Colitis

Hong J, Kim MS, Kim JS, Park H, Ko DH, Hwang SH, Oh HB

A 67-year-old man previously diagnosed with ulcerative colitis complained of difficulty in defecation and underwent balloon dilatation of rectum, but the procedure failed. The patient was transferred to a surgical...
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Diagnosis of Systemic Scleroderma in a Patient with Leg Ulcer

Ju GS, Son KM, Choi WY, Cheon JS

Systemic scleroderma is an autoimmune disease that affects connective tissue in internal organs and the skin with thickening and fibrosis. When afflicting internal organs, the disease leads to reduced quality...
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Epinephrine Infiltration and the Incidence of Bleeding Complications after Surgical Debridement of Pressure Ulcers with Negative Pressure Wound Therapy

Kim YH, Kim H, Cheon JH, Kang DH

BACKGROUND: For reducing intraoperative bleeding, epinephrine is commonly used as a vasoconstrictor with infiltration anesthesia. However, the effects of epinephrine on postoperative bleeding complications are still a matter of debate....
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Efficacy of the Mobile Three-Dimensional Wound Measurement System in Pressure Ulcer Assessment

Jun D, Choi H, Kim J, Lee M, Kim S, Jo D, Kim C, Shin D

BACKGROUND: Clinically assessing the changing status of wounds is important in determining management of pressure ulcers. A mobile three-dimensional measurement system (3DWMS) with a laser-assisted sensor camera was recently introduced...
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