Korean J Gastrointest Endosc.  2008 Sep;37(3):227-230.

A Case of Protein Loosing Enteropathy Associated with Pseudomembranous Colitis in a Patient with Peritonitis

Affiliations
  • 1Department of Internal Medicine, Dae Dong Hospital, Busan, Korea. janekim73@medigate.net

Abstract

Pseudomembranous colitis can be induced by the therapeutic or prophylactic use of antibiotics, and antibiotics- induced colitis has become a severe clinical problem. Protein?loosing enteropathy is associated with an abnormal, excessive loss of serum proteins into the gastrointestinal tract, and this leads to hypoproteinemia, including hypoalbuminemia, edema and diarrhea. We present here a case of protein?loosing enteropathy that was induced by pseudomembranous colitis, and this was induced by the use of antibiotics. Patients with chronic renal disease and peritonitis show hypoalbuminemia and edema. We experienced a patient who displayed edema, hypoalbuminemia, diarrhea and a fever for several days after the use for antibiotics for treating his peritonitis. We made the diagnosis of protein-loosing enteropathy complicated by psuedomembranous colitis. In a patient with peritonitis, uncontrolled edema and diarrhea, and the patient's hypoalbuminemia is continued, we must consider the possibility that the patient has protein-loosing enteropathy, and we should examine the total protein level and the alpha 1-antitrypsin clearance.

Keyword

Pseudomembranous colitis; Protein?loosing enteropathies; Peritonitis; alpha 1-antitrypsin clearance

MeSH Terms

alpha 1-Antitrypsin
Anti-Bacterial Agents
Blood Proteins
Colitis
Diarrhea
Edema
Enterocolitis, Pseudomembranous
Fever
Gastrointestinal Tract
Humans
Hypoalbuminemia
Hypoproteinemia
Peritonitis
Renal Insufficiency, Chronic
Anti-Bacterial Agents
Blood Proteins
alpha 1-Antitrypsin
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