- Lovastatin derivative dehydrolovastatin ameliorates ulcerative colitis in mice by suppressing NF-κB and inflammatory cytokine expression
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Zhang X, Deng QH, Deng JH, Wang SJ, Chen Q
- KMID: 2471035
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):137-147.
- doi: 10.4196/kjpp.2020.24.2.137
Ulcerative colitis (UC) is associated with intestinal immune imbalance and inflammatory response. Because dehydrolovastatin (DLVT), a derivative of lovastatin, has been recently shown to inhibit inflammation and relieve immune arthritis... -
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- An Atypical Extraintestinal Manifestation in a Child with Ulcerative Colitis: Cutaneous Leukocytoclastic Vasculitis
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Oh SJ, Choi Y, Kim CR, Park JH, Lee JH, Lee DY
- KMID: 2467210
- Ann Dermatol.
- 2020 Feb;32(1):90-91.
- doi: 10.5021/ad.2020.32.1.90
No abstract available. -
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- Effect of Sodium Cromoglycate on Acetic Acid-induced Ulcerative Colitis in Mice
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Ghafouri Z, Seyyedian , Nikbakht J, Kouhsari E, Bayat S, Zargar H, Houshmand
- KMID: 2471138
- Korean J Gastroenterol.
- 2020 Jan;75(1):39-45.
- doi: 10.4166/kjg.2020.75.1.39
BACKGROUND/AIMS: Ulcerative colitis (UC) is a type of inflammatory bowel disease that mainly involves the colon. Thus far, glucocorticoids and amino-salicylate have been the main treatment. METHODS: To assess drugs with... -
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- Comparison of Real-World Outcomes of Infliximab versus Adalimumab in Biologic-Naïve Korean Patients with Ulcerative Colitis: A Population-Based Study
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Han M, Jung YS, Cheon JH, Park S
- KMID: 2466335
- Yonsei Med J.
- 2020 Jan;61(1):48-55.
- doi: 10.3349/ymj.2020.61.1.48
PURPOSE: Data on the comparative effectiveness of infliximab (IFX) or adalimumab (ADA) in patients with ulcerative colitis (UC) are extremely limited, especially in the Asian population. We compared clinically important... -
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- Implication of Porphyromonas gingivalis in colitis and homeostasis of intestinal epithelium
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Seo Y, Oh SJ, Ahn JS, Shin YY, Yang JW, Kim HS
- KMID: 2470016
- Lab Anim Res.
- 2019 Dec;35(4):187-193.
- doi: 10.1186/s42826-019-0029-6
Emerging evidences have reported that periodontitis can be a risk factor for the pathogenesis of various systemic diseases. Porphyromonas gingivalis (Pg), one of the crucial pathogens in chronic periodontitis, has... -
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- Knowledge and Viewpoints on Biosimilar Monoclonal Antibodies among Asian Physicians: Comparison with European Physicians
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Park SK, Moon W, Kim ES, Park SH, Park DI
- KMID: 2469908
- Korean J Gastroenterol.
- 2019 Dec;74(6):333-340.
- doi: 10.4166/kjg.2019.74.6.333
BACKGROUND/AIMS: Current knowledge and viewpoints regarding biosimilars among physicians in Asia are unknown, even though these were investigated by European Crohn's and Colitis Organization (ECCO) members in 2013 and 2015.... -
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- Characteristics of Faecal Microbiota in Korean Patients with Clostridioides difficile-associated Diarrhea
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Jeon YD, Ann HW, Lee WJ, Kim JH, Seong H, Kim JH, Ahn JY, Jeong SJ, Ku NS, Yeom JS, Yong D, Lee K, Choi JY
- KMID: 2466469
- Infect Chemother.
- 2019 Dec;51(4):365-375.
- doi: 10.3947/ic.2019.51.4.365
BACKGROUND: The intestinal microbiota plays an important role in the pathogenesis of Clostridioides difficile-associated diarrhea, and regional and racial characteristics influence the microbiome composition and diversity. We investigated the intestinal... -
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- Immunosuppressive Effect of Exosomes from Mesenchymal Stromal Cells in Defined Medium on Experimental Colitis
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Ma ZJ, Wang YH, Li ZG, Wang Y, Li BY, Kang HY, Wu XY
- KMID: 2465884
- Int J Stem Cells.
- 2019 Nov;12(3):440-448.
- doi: 10.15283/ijsc18139
BACKGROUND AND OBJECTIVES: The exosomes released by mesenchymal stromal cells (MSCs) in classical FBS-containing media have been demonstrated as an alternative, cell-free therapy in various diseases including inflammatory bowel disease... -
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- Perspectives on Current and Novel Treatments for Inflammatory Bowel Disease
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Na SY, Moon W
- KMID: 2464308
- Gut Liver.
- 2019 Nov;13(6):604-616.
- doi: 10.5009/gnl19019
New therapeutic strategies in inflammatory bowel disease (IBD) have shifted from symptom control towards treat-to-target algorithms in order to optimize treatment results. The treatment of IBD has evolved with the... -
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- Eosinophilic Colitis
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Cho B, Son SM, Yoon SM
- KMID: 2464189
- Korean J Gastroenterol.
- 2019 Nov;74(5):295-297.
- doi: 10.4166/kjg.2019.74.5.295
No abstract available. -
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- Quality of information on the Internet for Korean patients with inflammatory bowel disease
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Yoon JS, Lee SJ, Kim ES, Kim SK, Jung MK, Lee HS, Kwon YH, Nam SY, Jeon SW, Jin S, Lee JS, Yeo SJ
- KMID: 2463479
- Korean J Intern Med.
- 2019 Nov;34(6):1215-1222.
- doi: 10.3904/kjim.2018.019
BACKGROUND/AIMS: The Internet is the main resource for health-related information. The incidence of inflammatory bowel disease (IBD) is rapidly increasing in Asian countries. However, the quality of websites for IBD... -
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- Burden of Psychiatric Disorders among Pediatric and Young Adults with Inflammatory Bowel Disease: A Population-Based Analysis
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Thavamani , Umapathi K, Khatana J, Gulati R
- KMID: 2462092
- Pediatr Gastroenterol Hepatol Nutr.
- 2019 Nov;22(6):527-535.
- doi: 10.5223/pghn.2019.22.6.527
PURPOSE: There is increasing prevalence of psychiatric disorders among inflammatory bowel Disease (IBD) population. Further, presence of psychiatric disorders has been shown as an independent predictor of quality of life... -
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- Infliximab biosimilar CT-P13 is interchangeable with its originator for patients with inflammatory bowel disease in real world practice
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Nakagawa T, Kobayashi , Nishikawa , Yamada F, Asai S, Sameshima , Suzuki Y, Watanabe M, Hibi T
- KMID: 2465816
- Intest Res.
- 2019 Oct;17(4):504-515.
- doi: 10.5217/ir.2019.00030
BACKGROUND/AIMS: An interim analysis of post-marketing surveillance of CT-P13, an infliximab biosimilar, was performed to evaluate its safety and efficacy in Japanese patients with inflammatory bowel disease. METHODS: Patients were prospectively... -
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- Polypharmacy is a risk factor for disease flare in adult patients with ulcerative colitis: a retrospective cohort study
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Wang J, Nakamura T, Tuskey AG, Behm BW
- KMID: 2465815
- Intest Res.
- 2019 Oct;17(4):496-503.
- doi: 10.5217/ir.2019.00050
BACKGROUND/AIMS: Polypharmacy is a common clinical problem with chronic diseases that can be associated with adverse patient outcomes. The present study aimed to determine the prevalence and patient-specific characteristics associated... -
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- Familial aggregation of inflammatory bowel disease in India: prevalence, risks and impact on disease behavior
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Banerjee R, Pal P, Hutfless S, Ganesh BG, Reddy DN
- KMID: 2465814
- Intest Res.
- 2019 Oct;17(4):486-495.
- doi: 10.5217/ir.2018.00174
BACKGROUND/AIMS: Information about familial aggregation of inflammatory bowel disease (IBD) in Asia is limited. We aimed to analyze the prevalence and risk of familial IBD in an Indian cohort and... -
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- Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan
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Yanagi T, Ushijima K, Koga H, Tomomasa T, Tajiri H, Kunisaki R, Isihige T, Yamada H, Arai K, Yoden A, Aomatsu T, Nagata S, Uchida K, Ohtsuka Y, Shimizu T
- KMID: 2465813
- Intest Res.
- 2019 Oct;17(4):476-485.
- doi: 10.5217/ir.2019.00027
BACKGROUND/AIMS: Tacrolimus is effective for refractory ulcerative colitis in adults, while data for children is sparse. We aimed to evaluate the effectiveness and safety of tacrolimus for induction and maintenance... -
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- Nutritional approach as therapeutic manipulation in inflammatory bowel disease
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Yoon JY
- KMID: 2465812
- Intest Res.
- 2019 Oct;17(4):463-475.
- doi: 10.5217/ir.2019.00078
Malnutrition is observed more frequently in patients with inflammatory bowel disease (IBD) than in the general population and associated with adverse clinical outcomes. This study aimed to review the current... -
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- Tacrolimus in pediatric ulcerative colitis: does it have a role?
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Kim S
- KMID: 2465809
- Intest Res.
- 2019 Oct;17(4):441-442.
- doi: 10.5217/ir.2019.00124
No abstract available. -
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- Severe Hypogammaglobulinemia Associated with Active Lupus Nephritis Treatment Resulting in Cytomegalovirus Infection
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Chung MK, Kang Y, Lee J
- KMID: 2459452
- J Rheum Dis.
- 2019 Oct;26(4):273-277.
- doi: 10.4078/jrd.2019.26.4.273
Patients with severe active lupus nephritis (LN) require immunosuppressive therapy to induce remission. However, the development of profound hypogammaglobulinemia causing cytomegalovirus (CMV) disease is a rare occurrence during standard immunotherapy.... -
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- A Case of Anti-Le(bH) Antibody Identified in a Patient with Ulcerative Colitis
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Hong J, Kim MS, Kim JS, Park H, Ko DH, Hwang SH, Oh HB
- KMID: 2458688
- Lab Med Online.
- 2019 Oct;9(4):254-257.
- doi: 10.3343/lmo.2019.9.4.254
A 67-year-old man previously diagnosed with ulcerative colitis complained of difficulty in defecation and underwent balloon dilatation of rectum, but the procedure failed. The patient was transferred to a surgical... -
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