Korean J Dermatol.
2004 Nov;42(11):1461-1465.
A Case of Hair Change and Acneiform Eruption Induced by ZD1839 (Iressa(R))
- Affiliations
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- 1Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea. daehun@snu.ac.kr
Abstract
- ZD1839 (Iressa(R)) is a new anticancer agent, a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor that blocks signal transduction pathway implicated in the proliferation and survival of cancer cells and other host-dependent process promoting cancer growth. But this agent can induce cutaneous side effects including acneiform eruption, dry skin, and hair abnormality, which is related with the interruption of normal epidermal and hair follicular kinetics. We report a case of hair change and acneiform eruption induced by ZD1839 (Iressa(R)).
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