Korean J Dermatol.  2005 Jun;43(6):843-845.

A Case of Spindle Cell Lipoma

Affiliations
  • 1Department of Dermatology, Chosun University Medical School, Gwangju, Korea. bsjung@chosun.ac.kr

Abstract

Spindle cell lipoma is an unusual and benign neoplasm, which normally occurs in middle age to older individuals oh the posterior neck, shoulders, and upper part of the back in the form of a solitary, slowly growing, painless, and subcutaneous nodule. We report a case of spindle cell lipoma on the right forearm of a 49-year-old female. Histopathologic examination revealed that the subcutaneous tumor was composed of mature fat cells and uniform spindle cells within a mucinous matrix. In some areas, the spindle cell proliferation was dominant due to variation in the ratio of spindle cells to mature fat cells. Vascularity was prominent in many parts of the tumor, and there were numerous mast cells scattered throughout the tumor. Immunohistochemically, the spindle cells were positive for vimentin and CD34, while S-100 protein and actin were not expressed.

Keyword

Spindle cell lipoma

MeSH Terms

Actins
Adipocytes
Cell Proliferation
Female
Forearm
Humans
Lipoma*
Mast Cells
Middle Aged
Mucins
Neck
S100 Proteins
Shoulder
Vimentin
Actins
Mucins
S100 Proteins
Vimentin
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