- Epithelial-Mesenchymal Transition-Inducing Factors Involved in the Progression of Lung Cancers
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Nam MW, Kim CW, Choi KC
- KMID: 2529886
- Biomol Ther.
- 2022 May;30(3):213-220.
- doi: 10.4062/biomolther.2021.178
Although there have been advances in cancer therapy and surgical improvement, lung cancer has the lowest survival rate (19%) at all stages. This is because most patients are diagnosed with... -
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- Gallic Acid Hindered Lung Cancer Progression by Inducing Cell Cycle Arrest and Apoptosis in A549 Lung Cancer Cells via PI3K/Akt Pathway
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Ko EB, Jang YG, Kim CW, Go RE, Lee HK, Choi KC
- KMID: 2526817
- Biomol Ther.
- 2022 Mar;30(2):151-161.
- doi: 10.4062/biomolther.2021.074
This study elucidates the anti-cancer potential of gallic acid (GA) as a promising therapeutic agent that exerts its effect by regulating the PI3K/Akt pathway. To prove our research rationale, we... -
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- Current Status of Mucosal Imaging with Narrow-Band Imaging in the Esophagus
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Chiam KH, Shin SH, Choi KC, Leiria F, Militz M, Singh R
- KMID: 2518443
- Gut Liver.
- 2021 Jul;15(4):492-499.
- doi: 10.5009/gnl20031
Recent advances in endoscopic imaging of the esophagus have revolutionized the diagnostic capability for detecting premalignant changes and early esophageal malignancy. In this article, we review the practical application of... -
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- First Clinical Cases of Spirometrosis in Two Cats in Korea
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Kim J, Ock Y, Yang K, Choe S, Park KM, Lee WK, Choi KC, Kim S, Kwak D, Lee SH
- KMID: 2515127
- Korean J Parasitol.
- 2021 Apr;59(2):153-157.
- doi: 10.3347/kjp.2021.59.2.153
This study reports the first two clinical cases of spirometrosis caused by Spirometra sp. in cats in Korea. In these two cases, the cats vomited, and long proglottids of tapeworm... -
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- Epidemiology of C5 Palsy after Cervical Spine Surgery: a 21-Center Study
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Oh JK, Hong JT, Kang DH, Kim SW, Kim SW, Kim YJ, Chung CK, Shin JJ, Yi S, Lee JK, Lee JH, Lee CH, Lee HJ, Chun HJ, Cho DC, Cho YE, Jin YJ, Choi KC, Han IH, Hyun SJ, Hur JW, Kim KJ
- KMID: 2463576
- Neurospine.
- 2019 Sep;16(3):558-562.
- doi: 10.14245/ns.1938142.071
OBJECTIVE: C5 palsy is a severe complication after cervical spine surgery, the pathophysiology of which remains unclear. This multicenter study investigated the incidence of C5 palsy following cervical spine surgery... -
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- In-Hospital and Post-Discharge Recovery after Acute Ischemic Stroke: a Nationwide Multicenter Stroke Registry-base Study
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Jang MU, Kang J, Kim BJ, Hong JH, Yeo MJ, Han MK, Lee BC, Yu KH, Oh MS, Choi KC, Lee SH, Hong KS, Cho YJ, Park JM, Cha JK, Kim DH, Park TH, Lee KB, Lee SJ, Lee J, Kim JT, Kim DE, Choi JC, Lee J, Lee JS, Gorelick P, Bae HJ
- KMID: 2458646
- J Korean Med Sci.
- 2019 Sep;34(36):e240.
- doi: 10.3346/jkms.2019.34.e240
BACKGROUND: Using data from a large national stroke registry, we aimed to investigate the incidence and determinants of in-hospital and post-discharge recovery after acute ischemic stroke and the independence of... -
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- Measuring the quality of life of the families of children with eczema in Hong Kong
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Cheng NS, Chau PC, Hon KL, Choi KC, Kung JS, Ng WG, Leung TF
- KMID: 2454160
- Asia Pac Allergy.
- 2019 Jul;9(3):e26.
- doi: 10.5415/apallergy.2019.9.e26
BACKGROUND: Eczema is the most common skin problem among children in Hong Kong. Previous studies have highlighted that the quality of life of the families of children with eczema influences... -
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- A Potential Therapy Using Engineered Stem Cells Prevented Malignant Melanoma in Cellular and Xenograft Mouse Models
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Heo JR, Hwang KA, Kim SU, Choi KC
- KMID: 2464425
- Cancer Res Treat.
- 2019 Apr;51(2):797-811.
- doi: 10.4143/crt.2018.364
PURPOSE: In the present study, human neural stem cells (hNSCs) with tumor-tropic behavior were used as drug delivery vehicle to selectively target melanoma. A hNSC line (HB1.F3) was transduced into... -
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- Roles of Mesenchymal Stem Cells in Tissue Regeneration and Immunomodulation
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Ayala-Cuellar AP, Kang JH, Jeung EB, Choi KC
- KMID: 2432063
- Biomol Ther.
- 2019 Jan;27(1):25-33.
- doi: 10.4062/biomolther.2017.260
Mesenchymal stem cells are classified as multipotent stem cells, due to their capability to transdifferentiate into various lineages that develop from mesoderm. Their popular appeal as cell-based therapy was initially... -
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- The Brain Donation Program in South Korea
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Kim Y, Suh YL, Kim SJ, Bae MH, Kim JB, Kim Y, Choi KC, Huh GY, Kim EJ, Lee JS, Kang HW, Shim SM, Lim HJ, Koh YH, Kim BC, Lee KH, Lee MC, Lee HW, Lim TS, Seeley WW, Kim HJ, Na DL, Lee KH, Seo SW
- KMID: 2426334
- Yonsei Med J.
- 2018 Dec;59(10):1197-1204.
- doi: 10.3349/ymj.2018.59.10.1197
PURPOSE: Obtaining brain tissue is critical to definite diagnosis and to furthering understanding of neurodegenerative diseases. The present authors have maintained the National Neuropathology Reference and Diagnostic Laboratories for Dementia... -
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- Treatment with Phytoestrogens Reversed Triclosan and Bisphenol A-Induced Anti-Apoptosis in Breast Cancer Cells
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Lee GA, Choi KC, Hwang KA
- KMID: 2421729
- Biomol Ther.
- 2018 Sep;26(5):503-511.
- doi: 10.4062/biomolther.2017.160
Triclosan (TCS) and bisphenol A (BPA) are endocrine-disrupting chemicals that interfere with the hormone or endocrine system and may cause cancer. Kaempferol (Kaem) and 3,3′-diindolylmethane (DIM) are phytoestrogens that play... -
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- Association between Smoking and Unintentional Injuries among Korean Adults
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Choi KC, Kim SA, Kim NR, Shin MH
- KMID: 2420887
- Chonnam Med J.
- 2018 Sep;54(3):184-189.
- doi: 10.4068/cmj.2018.54.3.184
Using a cross-sectional representative national survey, we evaluated the relationship between cigarette smoking and unintentional injuries among Korean adults. We used data from the 2009 Korean Community Health Survey. Smoking... -
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- Collagen-Induced Arthritis Analysis in Rhbdf2 Knockout Mouse
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Lee MY, Kang JS, Go RE, Byun YS, Wi YJ, Hwang KA, Choi JH, Kim HC, Choi KC, Nam KH
- KMID: 2421739
- Biomol Ther.
- 2018 May;26(3):298-305.
- doi: 10.4062/biomolther.2017.103
Rhomboid family member 2 gene (Rhbdf2) is an inactive homologue lacking essential catalytic residues of rhomboid intramembrane serine proteases. The protein is necessary for maturation of tumor necrosis factor-alpha (TNF-α)... -
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- Pathological Significance of Tissue Trapped in Retrieved OptEase Vena Cava Filter at 18th Day after Installation in Patient with Deep Vein Thrombosis
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Park SM, Son JW, Hong KS, Choi KC
- KMID: 2419128
- Yonsei Med J.
- 2017 May;58(3):662-664.
- doi: 10.3349/ymj.2017.58.3.662
The retrievable type of inferior vena cava filter has been widely used to prevent pulmonary thromboembolism in patients with deep vein thrombosis and contraindication of anticoagulation. Physicians make considerable efforts... -
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- Early Detection of Hidden Adenocarcinoma through the Prompt Pericardiocentesis in Patient with Small Pericardial Effusion
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Shinebayar B, Gill SY, Jeong H, Choi KC, Hong J, Park SM
- KMID: 2379504
- Ewha Med J.
- 2017 Apr;40(2):91-93.
- doi: 10.12771/emj.2017.40.2.91
Pericardial drainage is an important diagnostic and therapeutic option in the symptomatic patient with large amount of pericardial effusion (PE). However, when the amount of PE is relatively small, physicians... -
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- Anti-proliferative Effect of Engineered Neural Stem Cells Expressing Cytosine Deaminase and Interferon-β against Lymph Node–Derived Metastatic Colorectal Adenocarcinoma in Cellular and Xenograft Mouse Models
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Park GT, Kim SU, Choi KC
- KMID: 2367506
- Cancer Res Treat.
- 2017 Jan;49(1):79-91.
- doi: 10.4143/crt.2015.503
PURPOSE: Genetically engineered stem cells may be advantageous for gene therapy against various human cancers due to their inherent tumor-tropic properties. In this study, genetically engineered human neural stem cells... -
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- Effects of Percutaneous Sacroplasty on Pain and Mobility in Sacral Insufficiency Fracture
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Choi KC, Shin SH, Lee DC, Shim HK, Park CK
- KMID: 2365588
- J Korean Neurosurg Soc.
- 2017 Jan;60(1):60-66.
- doi: 10.3340/jkns.2016.0505.010
OBJECTIVE: Sacral insufficiency fracture (SIF) contributes to severe low back pain. Prolonged immobilization resulting from SIF can cause significant complications in the elderly. Sacroplasty, a treatment similar to vertebroplasty, has... -
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- Clinical Evaluation of Rapid Diagnostic Test Kit for Scrub Typhus with Improved Performance
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Kim YJ, Park S, Premaratna R, Selvaraj S, Park SJ, Kim S, Kim D, Kim MS, Shin DH, Choi KC, Kwon SH, Seo W, Lee NT, Kim SH, Kang HK, Kim YW
- KMID: 2373744
- J Korean Med Sci.
- 2016 Aug;31(8):1190-1196.
- doi: 10.3346/jkms.2016.31.8.1190
Diagnosis of scrub typhus is challenging due to its more than twenty serotypes and the similar clinical symptoms with other acute febrile illnesses including leptospirosis, murine typhus and hemorrhagic fever... -
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- iRhoms; Its Functions and Essential Roles
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Lee MY, Nam KH, Choi KC
- KMID: 2170521
- Biomol Ther.
- 2016 Mar;24(2):109-114.
- doi: 10.4062/biomolther.2015.149
In Drosophila, rhomboid proteases are active cardinal regulators of epidermal growth factor receptor (EGFR) signaling pathway. iRhom1 and iRhom2, which are inactive homologs of rhomboid intramembrane serine proteases, are lacking... -
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- Real-Time Quaking-Induced Conversion Analysis for the Diagnosis of Sporadic Creutzfeldt-Jakob Disease in Korea
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Park JH, Choi YG, Lee YJ, Park SJ, Choi HS, Choi KC, Choi EK, Kim YS
- KMID: 2364926
- J Clin Neurol.
- 2016 Jan;12(1):101-106.
- doi: 10.3988/jcn.2016.12.1.101
BACKGROUND AND PURPOSE: The level of 14-3-3 protein in the cerebrospinal fluid (CSF) is increased in Creutzfeldt-Jakob disease (CJD) patients, which has led to it being used as a clinical... -
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