- Case Report of Nodular Fasciitis in the Conjunctiva
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Kim JH, Na KS, Park CH, Lee SJ, Oh TH, Kim HS
- KMID: 2471773
- J Korean Ophthalmol Soc.
- 2020 Mar;61(3):303-306.
- doi: 10.3341/jkos.2020.61.3.303
PURPOSE: We report a case of nodular fasciitis of the conjunctiva that has not been previously reported in the Republic of Korea. CASE SUMMARY: A 18-year-old female patient presented with a... -
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- Duodenal Leiomyosarcoma Presenting with Gastrointestinal Bleeding and Obstruction: A Case Report
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Hong SM, Kim GH, Kim D, Lee S
- KMID: 2471148
- Korean J Gastroenterol.
- 2020 Feb;75(2):94-97.
- doi: 10.4166/kjg.2020.75.2.94
Duodenal leiomyosarcoma is a rare condition with a poor prognosis. Early diagnosis of duodenal leiomyosarcoma is challenging because it presents with nonspecific symptoms and endoscopic biopsies usually do not enable... -
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- Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells
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Kang SH, Kim SW, Kim KJ, Cho KH, Park JW, Kim CD, Do JY
- KMID: 2469377
- Kidney Res Clin Pract.
- 2019 Dec;38(4):472-480.
- doi: 10.23876/j.krcp.19.049
BACKGROUND: We investigated the effects of tranilast on epithelial-to-mesenchymal transition (EMT) in an animal model and on the EMT signaling pathway in human peritoneal mesothelial cells (HPMCs). METHODS: We performed in... -
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- Docosahexaenoic Acid Inhibits Expression of Fibrotic Mediators in Mice With Chronic Pancreatitis
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Lee S, Jeong YK, Lim JW, Kim H
- KMID: 2468813
- J Cancer Prev.
- 2019 Dec;24(4):233-239.
- doi: 10.15430/JCP.2019.24.4.233
BACKGROUND: Chronic pancreatitis (CP) is an irreversible progressive disease that destroys exocrine parenchyma, which are replaced by fibrous tissue. As pancreatic fibrosis is a key feature of CP, reducing fibrotic... -
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- Spreading Shape and Area Regulate the Osteogenesis of Mesenchymal Stem Cells
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Zhao Y, Sun Q, Wang S, Huo B
- KMID: 2467050
- Tissue Eng Regen Med.
- 2019 Dec;16(6):573-583.
- doi: 10.1007/s13770-019-00213-y
BACKGROUND: Mesenchymal stem cells (MSCs) have strong self-renewal ability and multiple differentiation potential. Some studies confirmed that spreading shape and area of single MSCs influence cell differentiation, but few studies... -
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- Isolation of Secretome with Enhanced Antifibrotic Properties from miR-214-Transfected Adipose-Derived Stem Cells
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Park JH, Kim OH, Kim KH, Hong HE, Seo H, Choi HJ, Ahn J, Lee TY, Kim SJ
- KMID: 2463682
- J Korean Med Sci.
- 2019 Nov;34(45):e273.
- doi: 10.3346/jkms.2019.34.e273
BACKGROUND: Secretome refers to the total set of molecules secreted or surface-shed by stem cells. The limitations of stem cell research have led numerous investigators to turn their attention to... -
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- Spindle cell myoepithelioma of the parotid gland
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Oh SJ, Moon D
- KMID: 2462491
- Arch Craniofac Surg.
- 2019 Oct;20(5):336-340.
- doi: 10.7181/acfs.2018.02341
Myoepithelioma was recognized as a histological distinct entity by the World Health Organization (WHO) in 1991. Myoepithelial cells are believed to be of ectodermal origin. In salivary glands, the myoepithelial... -
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- Mesenchymal Stem Cells Ameliorate Renal Inflammation in Adriamycin-induced Nephropathy
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Kim HS, Lee JS, Lee HK, Park EJ, Jeon HW, Kang YJ, Lee TY, Kim KS, Bae SC, Park JH, Han SB
- KMID: 2461200
- Immune Netw.
- 2019 Oct;19(5):e36.
- doi: 10.4110/in.2019.19.e36
Mesenchymal stem cells (MSCs) ameliorate the renal injury in Adriamycin (ADR)-induced nephropathy, but the mechanisms underlying their efficacy remain incompletely understood. In this study, we demonstrated that MSCs increased the... -
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- Role of Hydrogen Sulfide in the Survival of Fibroblasts and Fibroblast-mediated Contraction of Collagen Gel
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Park HJ, Kim JW
- KMID: 2460516
- J Korean Ophthalmol Soc.
- 2019 Oct;60(10):975-981.
- doi: 10.3341/jkos.2019.60.10.975
PURPOSE: To investigate the role of hydrogen sulfide in the survival and collagen gel contraction of cultured human Tenon's capsule fibroblasts (HTCFs). METHODS: Primarily cultured HTCFs were exposed to 0, 100,... -
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- Immunohistochemical Expression of Epithelial-Mesenchymal Transition Markers in Early Gastric Cancer: Cancer Tissue versus Noncancer Tissue
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Jung HJ, Hong SJ, Kim SH
- KMID: 2464668
- Clin Endosc.
- 2019 Sep;52(5):464-471.
- doi: 10.5946/ce.2018.181
BACKGROUND/AIMS: Epithelial-mesenchymal transition (EMT) is a developmental process, wherein the epithelial cells show reduced intercellular adhesions and acquire migratory fibroblastic properties. EMT is associated with downregulation in epithelial marker expression,... -
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- Effect of Relaxin Expression from an Alginate Gel-Encapsulated Adenovirus on Scar Remodeling in a Pig Model
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Yun IS, Kang E, Ahn HM, Kim YO, Rah DK, Roh TS, Lee WJ, Yun CO
- KMID: 2457481
- Yonsei Med J.
- 2019 Sep;60(9):854-863.
- doi: 10.3349/ymj.2019.60.9.854
PURPOSE: Relaxin (RLX) is a transforming growth factor-β1 (TGF-β1) antagonist that is believed to function as a potent collagen re-arranger and a major suppressor of extracellular matrix components. Adenoviruses (Ads)... -
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- Arg-Leu-Tyr-Glu Suppresses Retinal Endothelial Permeability and Choroidal Neovascularization by Inhibiting the VEGF Receptor 2 Signaling Pathway
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Park W, Baek YY, Kim J, Jo DH, Choi S, Kim JH, Kim T, Kim S, Park M, Kim JY, Won MH, Ha KS, Kim JH, Kwon YG, Kim YM
- KMID: 2456222
- Biomol Ther.
- 2019 Sep;27(5):474-483.
- doi: 10.4062/biomolther.2019.041
Vascular endothelial growth factor (VEGF) plays a pivotal role in pathologic ocular neovascularization and vascular leakage via activation of VEGF receptor 2 (VEGFR2). This study was undertaken to evaluate the... -
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- Survey of IgE Reactivity to Nonbiting Midges in Korea and Identification of IgE-Binding Protein
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Yi MH, Kim JY, Jeong KY, Ree HI, Yong TS
- KMID: 2452755
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):644-654.
- doi: 10.4168/aair.2019.11.5.644
PURPOSE: Chironomids (nonbiting midges) are widely and abundantly distributed near ponds, rivers, and artificially dammed pools used for irrigation. Chironomids contain allergens and cause airway allergy in humans. In this... -
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- Prevalence of Actinic Keratosis on a Facial Aesthetic Unit
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Kim JB, Choi HM, Kim SM, Ro BI, Cho HK
- KMID: 2457698
- Korean J Dermatol.
- 2019 Aug;57(7):410-411.
No abstract available. -
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- Mechanical and Mechanosensing Properties of Tumor Affected Bone Cells Were Inhibited via PI3K/Akt Pathway
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Lee T
- KMID: 2457437
- J Bone Metab.
- 2019 Aug;26(3):179-191.
- doi: 10.11005/jbm.2019.26.3.179
BACKGROUND: Osteolytic metastasis is a common destructive form of metastasis, in which there is an increased bone resorption but impaired bone formation. It is hypothesized that the changed mechanical properties... -
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- Diverse Effects of Small Molecule Inhibitors on Actin Cytoskeleton Dynamics in HIV-1 Infection
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Shin Y, Choi BS, Kim KC, Kim K, Yoon CH
- KMID: 2452048
- J Bacteriol Virol.
- 2019 Jun;49(2):69-80.
- doi: 10.4167/jbv.2019.49.2.69
The dynamics of the actin cytoskeleton plays a pivotal role in the process of cell division, the transportation of organelles, vesicle trafficking and cell movement. Human immunodeficiency virus type 1... -
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- Effect of Manuka Honey on Transforming Growth Factor Beta-1-Induced Extracelluar Matrix Production in Nasal Polyp Derived Fibroblasts
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Kil BK, Kim BM, Kang BJ, Ye MK, Shin SH
- KMID: 2451614
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2019 Jun;62(6):336-342.
- doi: 10.3342/kjorl-hns.2018.00682
BACKGROUND AND OBJECTIVES: Manuka honey has anti-microbial, anti-inflammatory, and anti-proliferative action with a high concentration of methylglyoxal compound. It is also effective in killing Staphylococcus aureus biofilm and effective for... -
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- Adult Xanthogranuloma: A Clinical, Histopathological, and Immunohistochemical Study of 19 Korean Cases
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Kwak HB, Jung ES, Park SW, Yun SK
- KMID: 2451585
- Korean J Dermatol.
- 2019 Jun;57(5):243-250.
BACKGROUND: Juvenile xanthogranuloma is a benign, self-limited disorder that usually occurs in infants and young children. Xanthogranuloma is rare in adults, and therefore studies reporting adult xanthogranuloma are limited. OBJECTIVE: We... -
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- A Therapeutic Strategy for Alzheimer's Disease Focused on Immune-inflammatory Modulation
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Kim SH, Noh MY, Kim HJ, Oh KW, Park J, Lee S, Moon Y, Kim YE, Bae JS, Jin HK, K-ARPI
- KMID: 2451000
- Dement Neurocogn Disord.
- 2019 Jun;18(2):33-46.
- doi: 10.12779/dnd.2019.18.2.33
Alzheimer's disease (AD), the most common form of dementia, has emerged as a major global public health challenge. However, the complexity of AD in its biological, genetic, and clinical aspects... -
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- Pentamidine Inhibits Titanium Particle-Induced Osteolysis In Vivo and Receptor Activator of Nuclear Factor-κB Ligand-Mediated Osteoclast Differentiation In Vitro
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Ihn HJ, Kim K, Cho HS, Park EK
- KMID: 2449237
- Tissue Eng Regen Med.
- 2019 Jun;16(3):265-273.
- doi: 10.1007/s13770-019-00186-y
BACKGROUND: Wear debris-induced osteolysis leads to periprosthetic loosening and subsequent prosthetic failure. Since excessive osteoclast formation is closely implicated in periprosthetic osteolysis, identification of agents to suppress osteoclast formation and/or... -
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