Korean J Perinatol.  2003 Jun;14(2):201-206.

A Case of Acute Monoblastic Leukemia developed during Pregnancy

• Kim SH
• Park KH
• Park JS
• Kim HH
• Chung SR
• Moon H
• Park MI

Abstract

Acute leukemias are among the most common malignant neoplasms of young woman, but paradoxically, their incidence complicating pregnancy is cited to be very low. In most situations, the course of the pregnancy does not seem to be affected by the presence of the leukemia. So early diagnosis and treatment of acute leukemia might be very important., since acute leukemia in a pregnant young woman poses an immediate threat to life and any treatment delay would significantly worsen the patient's prognosis. We report a 37-year-old female who had symptoms and signs of acute leukemia such as vaginal spotting and leukemia cutis and was diagnosed as acute monoblastic leukemia M5(FAB) in January 2002 with 25 weeks' pregnancy. This case represents the use of combination chemotherapy successfully resulted in complete remission in the second trimester without any adverse impact on the fetus in uterus.

Keyword

Acute leukemia; Second trimester; Combination chemotherapy

MeSH Terms

Adult
Drug Therapy, Combination
Early Diagnosis
Female
Fetus
Humans
Incidence
Leukemia
Leukemia, Monocytic, Acute*
Metrorrhagia
Pregnancy Trimester, Second
Pregnancy*
Prognosis
Uterus