Korean J Pediatr.
2005 Sep;48(9):920-923.
Epilepsy and Oxygen Free Radicals
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- 1Department of Pediatrics, College of Medicine, Chungbuk National University, Cheongju, Korea. wskim@chungbuk.ac.kr
Abstract
- Epilepsy is a neurological disorder from many molecular and biochemical responses. In the underlying mechanism, free radicals play an important role in seizure initiation and seizure-induced brain damage. Excessive production of oxygen free radicals and other radical species have been implicated in the development of seizures under pathological conditions and linked to seizure-induced neurodegeneration.
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