Korean J Pediatr Gastroenterol Nutr.
2005 Sep;8(2):226-232.
A Case of Gastric Outlet Obstruction Complicated by Peptic Ulcer Secondary to Non-Steroidal Anti-Inflammatory Drug (NSAID)
- Affiliations
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- 1Department of Pediatrics, Bundang Jesaeng General Hospital, Seongnam, Korea. babydr@chol.com
- 2Department of Pathology, Bundang Jesaeng General Hospital, Seongnam, Korea.
Abstract
- Peptic ulcer disease complicated with gastric outlet obstruction is rare in children. Even though NSAIDs have been reported to cause various adverse events, they are still regarded as safe and, therefore, widely utilized in children. In the past, pediatric patients who were at risk of seizure due to high fever, were treated with dipyrone (Metamizole sodium) injection which inhibits cyclooxygenase-1 and inhibit prostaglandin, to weaken the gastro-duodenal defensive mechanism. A case of an infant with multiple esophagogatroduodenal ulcers and bleeding caused by NSAID complicated with gastric outlet obstruction is reported in this paper.
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