Korean J Med.  2015 Dec;89(6):746-751. 10.3904/kjm.2015.89.6.746.

A Case of Intravascular Large B-cell Lymphoma Mimicking Systemic Lupus Erythematosus

Affiliations
  • 1Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea.
  • 2Division of Rheumatology, Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea. cptmiller@cnuh.co.kr
  • 3Division of Hemato-oncology, Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea.
  • 4Department of Pathology, Chungnam National University Hospital, Daejeon, Korea.

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of non-Hodgkin's lymphoma (NHL) and that progresses rapidly and is usually fatal. Because it usually presents with nonspecific symptoms, such as fever, the early diagnosis of IVLBCL is very difficult and it is often misdiagnosed as another disease. Systemic lupus erythematosus (SLE) is an autoimmune disease that affects various organs. The clinical manifestation of SLE ranges from rash and arthritis through anemia and thrombocytopenia to serositis, nephritis, seizures, and psychosis. Thus, it can be easily confused with many other disorders. We report a case of IVLBCL mimicking SLE in the initial diagnosis.

Keyword

Lymphoma; Lupus erythematosus, Systemic

MeSH Terms

Anemia
Arthritis
Autoimmune Diseases
B-Lymphocytes*
Diagnosis
Early Diagnosis
Exanthema
Fever
Lupus Erythematosus, Systemic*
Lymphoma
Lymphoma, B-Cell*
Lymphoma, Non-Hodgkin
Nephritis
Psychotic Disorders
Seizures
Serositis
Thrombocytopenia
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