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Comparison Between the SFTS-QS Kit and the PowerChek SFTSV Real-time PCR Kit for the Detection of Severe Fever With Thrombocytopenia Syndrome Virus

Yoo IY, Kim JY, Yoon YK, Huh HJ, Lee NY

The recent increase in severe fever with thrombocytopenia syndrome (SFTS) cases has led to the development of the SFTS-QS kit (MiCoBioMed, Seongnam, Korea) for detecting the SFTS virus (SFTSV, now...
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Clinical Score System to Differentiate Severe Fever with Thrombocytopenia Syndrome Patients from Patients with Scrub Typhus or Hemorrhagic Fever with Renal Syndrome in Korea

Heo DH, Kang YM, Song KH, Seo JW, Kim JH, Chun JY, Jun KI, Kang CK, Moon SM, Choe PG, Park WB, Bang JH, Kim ES, Kim HB, Park SW, Oh WS, Kim NJ, Oh MD

BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with high mortality in East Asia. This study aimed to develop, for primary care providers, a prediction score...
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Clinical Effects of Hypomethylating Agents in Patients with Newly Diagnosed Myelodysplastic Syndrome Who Received DNA-Damaging Chemotherapy for Metastatic Breast Cancer

Baek DW, Lee SJ, Sohn SK, Moon JH, Chae YS

The cumulative risk of therapy-related myelodysplastic syndrome (t-MDS) in breast cancer patients exposed to chemotherapy and/or radiotherapy is significantly high compared to that in other cancer patients. This report reviews...
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Anesthetic Experience of Cesarean Section in Evans Syndrome

Cho A

Evans syndrome is an uncommon condition defined by the combination of immune thrombocytopenia and autoimmune hemolytic anemia in the absence of known underlying cause. Association of Evans syndrome with pregnancy...
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Clinical Features of Disseminated Intravascular Coagulation With Spontaneous Ruptured Primary Renal Angiosarcoma

Yu SH, Lee HJ, Kang TW

Angiosarcoma is a rare malignant tumor accounting for less than 2% of all soft tissue sarcomas. Primary angiosarcoma of the kidney is an extremely rare but a highly aggressive tumor...
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Four Year Surveillance of the Vector Hard Ticks for SFTS, Ganghwa-do, Republic of Korea

Kim-Jeon M, Jegal S, Jun H, Jung H, Park SH, Ahn SK, Lee J, Gong YW, Joo K, Kwon MJ, Roh JY, Lee WG, Bahk YY, Kim TS

The seasonal abundance of hard ticks that transmit severe fever with thrombocytopenia syndrome virus was monitored with a collection trap method every April to November during 2015–2018 and with a...
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Safety Profile and Therapeutic Efficacy of One Cycle of Lu177-PSMA in End-Stage Metastatic Castration-Resistant Prostate Cancer Patients with Low Performance Status

Gupta M, Choudhury , Rawal S, Karthikeyan G, Talwar V, Dutta KD, Singh A

PURPOSE: The aim of this study was to evaluate safety and therapeutic efficacy of lutetium 177 prostate-specific membrane antigen (Lu-177-PSMA) in metastatic castration-resistant prostate cancer (mCRPC) patients with low performance...
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Screening and Treatment of Latent Tuberculosis Infection among Healthcare Workers at a Referral Hospital in Korea

Park SY, Lee E, Lee EJ, Kim TH, Kim YK

BACKGROUND: Healthcare workers (HCWs) have a high risk of tuberculosis (TB) infection. Since August 2017, Korea has mandated the testing of latent TB infection (LTBI) and recommended treatment from HCWs...
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Seroprevalence of Severe Fever with Thrombocytopenia Syndrome in the Agricultural Population of Jeju Island, Korea, 2015–2017

Yoo JR, Heo ST, Kim M, Song SW, Boo JW, Lee KH

BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne zoonotic disease that is caused by the SFTS virus (SFTSV), and exhibits an overall mortality rate of approximately 20.0% in...
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Early Detection and Successful Treatment of Vertically Transmitted Fulminant Enteroviral Infection Associated with Various Forms of Arrhythmia and Severe Hepatitis with Coagulopathy

Lee SR, Ko SY, Yoon SY, Lee YK, Shin SM

Enteroviral infections are common in neonates. One important infection pathway is vertical transmission from an infected mother to her neonate. Here, we report the early detection and successful treatment of...
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Anemic Retinopathy after Chemotherapy

Lee SC, Oh BL

PURPOSE: To report a case of anemic retinopathy after chemotherapy. CASE SUMMARY: A 32-year-old male presented with visual disturbance in both eyes. He had been diagnosed with testicular cancer and had...
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Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline

Kim JS, Kim JY

Neonatal thrombocytopenia, defined as platelet counts of less than 150,000/µL, is a frequent hematologic abnormality in neonatal period. Differential diagnosis of neonatal thrombocytopenia may be challenging to pediatric hematologists and...
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Co-Infection of Scrub Typhus and Human Granulocytic Anaplasmosis in Korea, 2006

Kim JH, Lee CS, Moon C, Kwak YG, Kim BN, Kim ES, Kang JM, Park WB, Oh MD, Park SW

BACKGROUND: Scrub typhus, severe fever with thrombocytopenia syndrome (SFTS) and human granulocytic anaplasmosis (HGA) are important arthropod-borne infectious diseases in Korea and share a common point that they are transmitted...
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Frequently Delayed Diagnosis and Misdiagnosis in MYH9-related Disorders: Data from Genetically Confirmed Cases of Korean Patients

Park CH, Kim YE, Lee KO, Kim SH, Oh KH, Kim I, Oh D, Kim HJ

MYH9-related disorders (MYH9RD) are autosomal-dominant disorders characterized by macrothrombocytopenia with or without leukocyte inclusion bodies or extra-hematological features, such as sensorineural deafness and renal impairment. MYH9RD can be misdiagnosed as...
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Severe Cutaneous Adverse Reactions to Antiepileptic Drugs: A Nationwide Registry-Based Study in Korea

Park CS, Kang DY, Kang MG, Kim S, Ye YM, Kim SH, Park HK, Park JW, Nam YH, Yang MS, Jee YK, Jung JW, Kim SH, Kim CW, Kim MY, Kim JH, Lee J, Lee JG, Kim SH, La HO, Kim MH, Park SJ, Koh YI, Lee SM, Kwon YE, Jin HJ, Kim HK, Kang HR, Choi JH, Korean Registry of Severe Cutaneous Adverse Reactions Consortium

PURPOSE: Severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) to antiepileptic drug (AED), are rare, but...
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Long-Term Efficacy and Safety of Partial Splenic Embolization in Hepatocellular Carcinoma Patients with Thrombocytopenia Who Underwent Transarterial Chemoembolization

Kim NH, Kim HJ, Cho YK, Hong HP, Kim BI

BACKGROUND: Performing transarterial chemoembolization (TACE) is difficult with the occurrence of thrombocytopenia in cirrhotic patients with hepatocellular carcinoma (HCC). We aimed to evaluate the long-term efficacy and safety of partial...
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Hemarthrosis Occurred after Arthroscopic Rotator Cuff Repair in a Chronic Renal Failure Patient with a Stenosis in an Ipsilateral Arteriovenous Fistula

Huh SH, Kim SJ, Park JY, Kang KR

Hemarthrosis occurring after arthroscopic surgery for lesions of the shoulder joint is a very rare complication that can develop due to an injury to the blood vessels when an anterior...
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Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome

Yoo JR, Kim SH, Kim YR, Lee KH, Oh WS, Heo ST

BACKGROUND/AIMS: Severe fever with thrombocytopenia syndrome (SFTS) is a viral hemorrhagic fever with a high fatality rate. However, effective treatments for SFTS cases not responded to supportive therapy have not...
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The Effect of Mycophenolate Mofetil on Non-Renal Manifestations in Systemic Lupus Erythematosus: Results from Korean Lupus Network Registry

Jung UH, Kwak SG, Choe JY, Lee SS, Kim SK

BACKGROUND: The objective of this study was to identify the effects of mycophenolate mofetil (MMF) on non-renal manifestations in systemic lupus erythematosus (SLE). METHODS: The study population comprised 439 SLE patients...
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Tocilizumab-induced Thrombocytopenia in Patients with Rheumatoid Arthritis

Lee JS, Oh JS, Hong S, Lee CK, Yoo B, Kim YG

OBJECTIVE: Interlukin-6 (IL-6) increases platelet count during inflammation and may act in a manner similar to thrombopoietin. Tocilizumab is a monoclonal antibody of the IL-6 receptor and widely used in...
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