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Initial Seizure Threshold in Brief-Pulse Bilateral Electroconvulsive Therapy in Patients with Schizophrenia or Schizoaffective Disorder

Jeong SH, Youn T, Lee Y, Jang JH, Jeong YW, Kim YS, Chung IW

OBJECTIVE: The present study aimed to report the initial seizure threshold (IST) of a brief-pulse bilateral electroconvulsive therapy (BP-BL ECT) in Korean patients with schizophrenia/schizoaffective disorder and to identify IST...
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Predicting Symptomatic and Functional Improvements over 1 Year in Patients with First-Episode Psychosis Using Resting-State Electroencephalography

Renaldi R, Kim M, Lee TH, Kwak YB, Tanra AJ, Kwon JS

OBJECTIVE: Although early intervention from the beginning of a psychotic episode is essential for a better prognosis, biomarkers predictive of symptomatic and functional improvement in early psychotic disorders are lacking....
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Diagnostic Issues of Depressive Disorders from Kraepelinian Dualism to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition

Park SC, Kim YK

Because the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) was mainly influenced by the neo-Kraepelinian approach, its categorical approach to defining mental disorders has been criticized from...
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Serum Prolactin and Bone Mineral Density in Schizophrenia: A Systematic Review

Lally J, Sahl AB, Murphy KC, Gaughran F, Stubbs B

The relationship between serum prolactin and bone mineral density (BMD) in schizophrenia is unclear. We conducted a literature review of databases from inception until December 2018 for cross-sectional, case-control, prospective...
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Factors Affecting Admission Type in Patients with Schizophrenia Spectrum

Park YJ, Ko MS, Kim KE, Jho KH, Nam HJ

OBJECTIVES: This study examined the admission type and its related factors among patients with psychotic disorders defined based on the revised mental health welfare law. METHODS: This study was conducted on...
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Childhood Onset of Anti-N-Methyl-D-Aspartate Receptor Encephalitis Without Teratoma Masquerading as a Psychotic Disorder

Yeum TS, Lee J, Park SY, Joen Y, Kim BN

  • KMID: 2452883
  • J Korean Acad Child Adolesc Psychiatry.
  • 2019 Jul;30(3):127-131.
  • doi: 10.5765/jkacap.180036
Many neurologic disorders manifest as psychiatric symptoms. Anti-N-Methyl-D-Aspartate (NMDA) receptor encephalitis is an autoimmune disease of the brain characterized by numerous neurological and psychiatric features. Despite being rare, its prevalence...
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Long-Term Grey Matter Changes in First Episode Psychosis: A Systematic Review

Gallardo-Ruiz R, Crespo-Facorro B, Setién-Suero E, Tordesillas-Gutierrez D

OBJECTIVE: To determine possible progressive changes of the grey matter at the first stages of the schizophrenia spectrum disorders, and to determine what regions are involved in these changes. METHODS: We...
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Psychiatric Symptoms in Systemic Lupus Erythematosus: Diagnosis and Treatment

Yoon S, Kang DH, Choi TY

According to the American College of Rheumatology classification, lupus erythematosus has five psychiatric manifestations, including cognitive dysfunction, mood disorder, anxiety disorder, psychosis, and acute confusional state, which are frequently accompanied...
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Protocol and Rationale: A 24-week Double-blind, Randomized, Placebo Controlled Trial of the Efficacy of Adjunctive Garcinia mangostana Linn. (Mangosteen) Pericarp for Schizophrenia

Turner A, McGrath JJ, Dean OM, Dodd S, Baker A, Cotton SM, Scott JG, Kavanagh B, Ashton MM, Walker AJ, Brown E, Berk M

OBJECTIVE: Garcinia mangostana Linn., commonly known as mangosteen, is a tropical fruit with a thick pericarp rind containing bioactive compounds that may be beneficial as an adjunctive treatment for schizophrenia....
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Physical Health Literacy and Health-related Behaviors in Patients with Psychosis

Kim SW, Park WY, Jhon M, Kim M, Lee JY, Kim SY, Kim JM, Shin IS, Yoon JS

OBJECTIVE: This study compared the levels of knowledge of physical illnesses and patterns of health behaviors between patients with psychosis and the general population. METHODS: A total of 712 participants were...
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Serum Levels of High Sensitivity C-reactive Protein in Drug-naïve First-episode Psychosis and Acute Exacerbation of Schizophrenia

Bolu A, Aydin MS, Akgün A, CoÅŸkun A, Garip B, Öznur T, Çelik C, Uzun Ã

OBJECTIVE: Findings about inflammatory processes in schizophrenia are increasing day by day. Inflammatory processes in schizophrenia are associated with both its etiology and clinical symptoms. Serum high-sensitivity C-reactive protein (hsCRP)...
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Peripheral Biomarkers for First-Episode Psychosis—Opportunities from the Neuroinflammatory Hypothesis of Schizophrenia

Trovão N, Prata J, VonDoellinger O, Santos S, Barbosa M, Coelho R

OBJECTIVE: Schizophrenia is a disabling disorder of unknown aetiology, lacking definite diagnostic method and cure. A reliable biological marker of schizophrenia is highly demanded, for which traceable immune mediators in...
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Recurrent Psychosis after Phentermine Administration in a Young Female: A Case Report

Jo HS, Wang SM, Kim JJ

Phentermine is a sympathomimetic amine, like amphetamine, which is one of the most often prescribed drugs for weight loss. Although exact mechanism of phentermine causing psychosis is still not clear,...
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Validation of the Korean Version of the Prodromal Questionnaire-Brief Version in Non-Help-Seeking Individuals

Jang YE, Lee TY, Hur JW, Kwon JS

OBJECTIVE: In this study, we examined the reliability and validity of the Korean version of the Prodromal Questionnaire-Brief (PQ-B), a self-report screening instrument for clinical high risk for psychosis (CHR). METHODS:...
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The Long-Acting Injectable Antipsychotics in Clinical Practice

Lee K

Symptomatic relapse is observed frequently and often associated with social and/or occupational decline that can be difficult to reverse in patients with schizophrenia. Several atypical antipsychotics, including risperidone, olanzapine, paliperidone,...
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New Insights into the Molecular and Cellular Mechanism of Antipsychotics

Kim SH

The serendipitous discovery of drugs with antipsychotic action has provided a clue to understanding the pathogenesis of psychotic disorders and to develop so called ‘antipsychotics’ drugs. From the ‘dopamine hypothesis’...
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Physical and Functional Interaction between 5-HT₆ Receptor and Nova-1

Kim SH, Seo M, Hwang H, Moon DM, Son GH, Kim K, Rhim H

5-HT₆ receptor (5-HT₆R) is implicated in cognitive dysfunction, mood disorder, psychosis, and eating disorders. However, despite its significant role in regulating the brain functions, regulation of 5-HT₆R at the molecular...
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Neuropsychiatric Symptoms of Multiple Sclerosis: State of the Art

Silveira C, Guedes R, Maia D, Curral R, Coelho R

Multiple Sclerosis (MS) is a chronic disabling neuroinflammatory disease. Psychiatric manifestations have a high prevalence in MS patients and may worsen the illness progression and the patients’ quality of life...
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Hypertension Induced by Aripiprazole Use in an Autistic Child Patient

Uzun AD, Sapmaz SY, Öztürk M, Kandemir H

Atypical antipsychotics in children and adolescents are widely used for aggression, emotional variability and psychosis treatment. Aripiprazole is also an atypical antipsychotic that increasingly used in children and adolescents with...
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Aripiprazole-induced Hepatitis: A Case Report

Castanheira L, Fernandes , Levy P, Coentre R

Aripiprazole is an atypical antipsychotic that acts as a partial agonist of dopamine type 2 receptors as well as 5-HT1A receptors. It is used in the treatment of schizophrenia and...
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