Korean J Med.
2016 Feb;90(2):144-147. 10.3904/kjm.2016.90.2.144.
Pulmonary Placental Transmogrification Presenting as a Small Lung Nodule
- Affiliations
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- 1Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea. imekkim@cha.ac.kr
- 2Division of Pulmonology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
- 3Department of Pathology, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
- KMID: 2268873
- DOI: http://doi.org/10.3904/kjm.2016.90.2.144
Abstract
- Pulmonary placental transmogrification (PT) is a rare lung disease that takes on the histologic appearance of placental chorionic villi. We herein report a case of PT in a 66-year-old woman who presented with a single nodule on chest radiography performed during a routine health examination. She had no complaints of any symptoms. Chest radiography showed a focal ill-defined nodular opacity in the right lower lobe; chest computed tomography revealed a 17-mm lobulated, focal irregular mass with fissural retraction in the right lower lobe, suggestive of lung cancer. Pathology of a percutaneous needle aspiration biopsy revealed papillary structures resembling placental villi. These were lined by cytotrophoblast-like cells and syncytiotrophoblasts. This characteristic pathologic finding led to a diagnosis of PT. PT of the lung is found mainly in bullous or cystic lesions. However, this patient presented with a single nodule on chest radiography.
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