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Two Cases of SARS-CoV-2-Positive Mothers and Their Newborns in Korea

Jin JH, Kim Y, Yoo J, Kim EH, Yoon SW

It is unclear how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects pregnant women and their fetuses or newborns. We report two infants born to mothers with coronavirus disease 2019...
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Unilateral Giant Bullae: Pulmonary Placental Transmogrification Should Be Kept in Mind: Case Reports

M. Hamad AM, M. Nosseir M, M. Alorainy S

Placental transmogrification is a peculiar clinical entity of the lung of uncertain etiology. We report 2 cases of pulmonary placental transmogrification in 2 patients of different nationalities. Both of them...
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Diagnosis of Intraplacental Choriocarcinoma after Fetal Death In Utero at Term Pregnancy: A Case Report with Literature Review

Lee EJ, Hong SY, Bae JY

Choriocarcinoma is a malignant disease that occurs in the chorionic villi and a type of gestational trophoblastic disease. It is a very rare occurrence in pregnant women. A 30-year-old primigravida...
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Conservative Management of Retained Placenta Accreta Postpartum

Joo EH, Ko JE, Lee Hl, Kim HC, Kim YR

Retained placenta accreta is difficult to diagnose in the series of processes involved in parturition. It is usually discovered after delivery, when massive and uncontrollable postpartum hemorrhage occurs. A histological...
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Probability Model of Massive Hemorrhage in Patients with Placenta Previa

Choi MG, Kim JW, Jin WH, Kim YH

Objective: The aim of this study was to identify the factors affecting massive hemorrhages in patients with placenta previa. We also made probability models and equations for massive hemorrhage. Methods: Seven...
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Placenta accreta spectrum-a catastrophic situation in obstetrics

Pegu B, Thiagaraju C, Nayak D, Subbaiah M

Placenta accreta is a significant obstetric complication in which the placenta is completely or focally adherent to the myometrium. The worldwide incidence of placenta accreta spectrum (PAS) is increasing day...
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JEG-3 placental cells in toxicology studies: a promising tool to reveal pregnancy disorders

Olivier E, Wakx A, Fouyet S, Dutot M, Rat P

Placental alterations are responsible for adverse pregnancy outcomes like preeclampsia and intrauterine growth restriction. And yet, placenta toxicology has not become a fully-f ledged toxicology field. Because placenta is very...
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Efficacy of Gene Modification in Placenta-Derived Mesenchymal Stem Cells Based on Nonviral Electroporation

Kim JY, Choi JH, Kim SH, Park H, Lee D, Kim GJ

Mesenchymal stem cell (MSC)-based therapy using gene delivery systems has been suggested for degenerative diseases. Although MSC-based clinical applications are effective and safe, the mode of action remains unclear. Researchers...
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Magnetic Resonance Imaging of Placenta Accreta Spectrum: A Step-by-Step Approach

Srisajjakul S, Prapaisilp P, Bangchokdee S

Placenta accreta spectrum (PAS) is an abnormal placental adherence or invasion of the myometrium or extrauterine structures. As PAS is primarily staged and managed surgically, imaging can only guide and facilitate...
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Articular Cartilage Regeneration Utilizing Decellularized Human Placental Scaffold, Mesenchymal Stem Cells and Platelet Rich Plasma

Özdemir E, Emet A, Hashemihesar R, Sinan Yürüker AC, Kılıc E, Çetinkaya DU, Turhan E

BACKGROUND: Articular cartilage repair has been a challenge in orthopedic practice due to the limited self-regenerative capability. Optimal treatment method for cartilage defects has not been defined. We investigated the...
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Upregulation of C-Reactive Protein by Placenta-Derived Mesenchymal Stem Cells Promotes Angiogenesis in A Rat Model with Cirrhotic Liver

Jun JH, Jung J, Kim JY, Hwang SG, Bae SH, Kim GJ

Background and Objectives: Liver cirrhosis is accompanied by abnormal vascular shunts. The Wnt pathway is essential for endothelial cell survival and proliferation. C-reactive protein (CRP), which is produced by hepatocyte,...
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Management of massive hemorrhage in pregnant women with placenta previa

Park HS, Cho HS

Patients with placenta previa are at risk for intra- and postpartum massive blood loss as well as increased risk of placenta accreta, a type of abnormal placental implantation. This condition...
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Significance of Clinical Findings of Patients with Placental Abruption

Jeong YY, Yun TH, Hong SY, Bae JY

Objective: Placental abruption is an extremely critical complication in pregnant women because it can result in poor maternal and neonatal outcomes. The exact criteria or obvious prognostic factors to diagnose...
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Role of potassium channels in female reproductive system

Kim JM, Song KS, Xu B, Wang T

Potassium channels are widely expressed in most types of cells in living organisms and regulate the functions of a variety of organs, including kidneys, neurons, cardiovascular organs, and pancreas among...
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Successful management of uncontrolled postpartum hemorrhage due to morbidly adherent placenta with Resuscitative endovascular balloon occlusion of the aorta during emergency cesarean section - A case report -

Ji SM, Cho C, Choi G, Song J, Kwon MA, Park JH, Kim S

Background: Morbidly adherent placenta (MAP) may cause life-threatening postpartum hemorrhage (PPH) requiring massive transfusions. Furthermore, it could endanger the lives of both mother and baby. Despite various efforts, such as...
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Is placental KISS-1 expression associated with first trimester abortion spontaneous?

Colak E, Ozcimen EE, Erinanç OH, Tohma YA, Ceran MU

Objective Several studies have examined biological markers during the first trimester to predict the maintenance of a healthy pregnancy. One such marker is kisspeptin, which is encoded by the KISS-1...
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Placental Mesenchymal Dysplasia Associated with Placenta Previa and Preterm Labor

Kim SJ, Yun HY, Shim SS, Kang HS, Hyun CL

Placental mesenchymal dysplasia is a rare placental vascular anomaly characterized by placentomegaly and grape-like vesicles and is recently recognized condition. This resembles partial molar pregnancy by ultrasonography. Placental mesenchymal dysplasia...
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Preconditioning of Human Decidua Basalis Mesenchymal Stem/Stromal Cells with Glucose Increased Their Engraftment and Anti-diabetic Properties

Basmaeil Y, Rashid MA, Khatlani T, AlShabibi M, Bahattab E, Abdullah ML, Abumary F, Kalionis B, Massoudi S, AbuMaree M

Background: Mesenchymal stem/stromal cells (MSCs) from the decidua basalis (DBMSCs) of the human placenta have important functions that make them potential candidates for cellular therapy. Previously, we showed that DBMSC...
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Effect of a Combined Hemostatic Technique during Cesarean Section in Placenta Previa

Lee DH, Choi WK, Park DJ, Jeong YJ, Lee JH

Objective Only a few methods, besides cesarean hysterectomy, are available for controlling intractable bleeding in placenta previa. We aimed to evaluate the effect of the combined hemostatic technique during cesarean section...
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Subsequent pregnancy outcomes according to the presence of acute histologic chorioamnionitis in women with spontaneous preterm delivery

Kim NK, Choi YJ, Hong S, Park JY, Oh KJ, Hong JS

OBJECTIVE: To compare subsequent pregnancy outcomes according to the presence of acute histologic chorioamnionitis (HCA) in women with spontaneous preterm delivery (SPTD). METHODS: Among 1,706 women who gave birth twice or...
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