Korean J Med.  2012 Jan;82(1):35-36.

FOLFOX-4 Combination Chemotherapy as a First-line Treatment in Patients with Advanced Gastric Cancer

Affiliations
  • 1Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea. shs7436@dsmc.or.kr

Abstract

The FOLFOX-4 regimen as first-line treatment in patients with advanced gastric cancer has not evidence of category 1 for prolongation of survival in patients with advanced gastric cancer. Therefore, the use is preferred in the second line. But, especially in elderly patients, FOLFOX regimen was active and well tolerated with lower toxicities. Further phase III study is warranted to evaluate the evidence for prolongation of survival in elderly patients or combination therapy with target agents in advanced gastric cancer.

Keyword

Stomach neoplasm; Chemotherapy; Oxaliplatin

MeSH Terms

Aged
Antineoplastic Combined Chemotherapy Protocols
Drug Therapy, Combination
Fluorouracil
Humans
Leucovorin
Organoplatinum Compounds
Stomach Neoplasms
Antineoplastic Combined Chemotherapy Protocols
Fluorouracil
Leucovorin
Organoplatinum Compounds
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