- Two Cases of Unresectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgical Resection
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Huh G, Chun JW, You MS, Paik WH, Lee SH, Kim YT, Ryu JK
- KMID: 2470444
- J Dig Cancer Res.
- 2019 Dec;7(2):61-64.
- doi: 10.0000/jdcr.2019.7.2.61
We report two cases of patients with unresectable pancreatic cancer treated with neoadjuvant chemotherapy and surgical resection. In the first case, main mass was located at the neck of the... -
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- Delayed Elimination After High-dose Methotrexate in Pediatric Patients with Acute Lymphoblastic Leukemia and Non-Hodgkin Lymphoma
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Yoon HW, Ree YS, Song HS, Kim JS, Son ES
- KMID: 2452858
- Korean J Clin Pharm.
- 2019 Jun;29(2):101-108.
- doi: 10.24304/kjcp.2019.29.2.101
BACKGROUND: High doses of methotrexate (MTX) are often used in various chemotherapy protocols to treat acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL) in children, but its delayed elimination increases... -
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- Protective effect of Korean red ginseng on oxaliplatin-mediated splenomegaly in colon cancer
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Kang J, Park JS, Ahn SG, Lim JH, Baik SH, Yoon DS, Lee KY, Jeong J
- KMID: 2419447
- Ann Surg Treat Res.
- 2018 Sep;95(3):161-167.
- doi: 10.4174/astr.2018.95.3.161
PURPOSE: This study investigated how adding Korean red ginseng extract (KRG) to folinic acid, fluorouracil and oxaliplatin (FOLFOX) chemotherapy affected the rate of splenomegaly in colon cancer. METHODS: This retrospective study... -
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- Hepatoid Carcinoma of the Pancreas Presenting as Acute Pancreatitis
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Shin SW, Sung YN, So H, Song E, Oh CR, Hong SM, Park DH
- KMID: 2435076
- Korean J Med.
- 2018 Aug;93(4):387-392.
- doi: 10.3904/kjm.2018.93.4.387
Hepatoid carcinoma is extrahepatic neoplasm showing similar morphologic, immunohistochemical features with hepatocellular carcinoma. It's a very rare disease and has been reported most frequently in the stomach. Herein, we report... -
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- The outcomes of intensified 5-fluorouracil plus leucovorin chemotherapy for preoperative chemoradiation in rectal cancers
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Ha N, Hong KD, Ji WB, Kim JS, Um JW
- KMID: 2405657
- Korean J Clin Oncol.
- 2017 Dec;13(2):147-151.
- doi: 10.14216/kjco.17023
PURPOSE: The clinical benefit of intensified neoadjuvant chemoradiotherapy (CRT) in rectal cancer has not been proved. We investigated clinical outcomes of intensified 5-fluorouracil plus leucovorin (5-FU/LV) chemotherapy. METHODS: We retrospectively analyzed... -
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- Retrospective analysis on the clinical efficacy of bevacizumab combined with FOLFOX4 in the first line treatment of metastatic colorectal cancer
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Lee EM, Park LC, Lee HS, Shin SH, Kim YS
- KMID: 2400260
- Kosin Med J.
- 2017 Dec;32(2):170-178.
- doi: 10.7180/kmj.2017.32.2.170
OBJECTIVES: The addition of bevacizumab to standard chemotherapy has been improved survival outcomes in patients with metastatic colorectal cancer. However, the combination of bevacizumab with oxaliplatin-based chemotherapy as first-line treatment... -
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- Simultaneous integrated boost intensity-modulated radiotherapy versus 3-dimensional conformal radiotherapy in preoperative concurrent chemoradiotherapy for locally advanced rectal cancer
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Bae BK, Kang MK, Kim JC, Kim MY, Choi GS, Kim JG, Kang BW, Kim HJ, Park SY
- KMID: 2393550
- Radiat Oncol J.
- 2017 Sep;35(3):208-216.
- doi: 10.3857/roj.2017.00353
PURPOSE: To evaluate the feasibility of simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) for preoperative concurrent chemoradiotherapy (PCRT) in locally advanced rectal cancer (LARC), by comparing with 3-dimensional conformal radiotherapy (3D-CRT). MATERIALS... -
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- A Randomized Phase II Study of Leucovorin/5-Fluorouracil with or without Oxaliplatin (LV5FU2 vs. FOLFOX) for Curatively-Resected, Node-Positive Esophageal Squamous Cell Carcinoma
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Lim SH, Shim YM, Park SH, Kim HK, Choi YS, Ahn MJ, Park K, Zo JI, Sun JM
- KMID: 2388327
- Cancer Res Treat.
- 2017 Jul;49(3):816-823.
- doi: 10.4143/crt.2016.417
PURPOSE: The optimal perioperative treatment for resectable esophageal squamous cell carcinoma (ESCC) remains controversial. We evaluated the efficacy and safety of leucovorin and 5-fluorouracil (LV5FU2) and LV5FU2 plus oxaliplatin (FOLFOX)... -
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- FGFR4 Arg388 Is Correlated with Poor Survival in Resected Colon Cancer Promoting Epithelial to Mesenchymal Transition
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Cho SH, Hong CS, Kim HN, Shin MH, Kim KR, Shim HJ, Hwang JE, Bae WK, Chung IJ
- KMID: 2388322
- Cancer Res Treat.
- 2017 Jul;49(3):766-777.
- doi: 10.4143/crt.2016.457
PURPOSE: Fibroblast growth factor receptor 4 (FGFR4) plays an important role in cancer progression during tumor proliferation, invasion, and metastasis. This study evaluated the prognostic role of FGFR4 polymorphism in... -
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- Chemotherapy for Biliary Tract Cancer
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Woo SM
- KMID: 2383410
- Korean J Gastroenterol.
- 2017 Mar;69(3):172-176.
- doi: 10.4166/kjg.2017.69.3.172
The term of biliary tract cancer (BTC) refers to all tumors that arise from the biliary tract or the biliary drainage system, including the intra- and extra-hepatic bile ducts as... -
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- Efficacy and Safety of Bolus 5-Fluorouracil and L-Leucovorin as Salvage Chemotherapy for Oral Fluoropyrimidine-Resistant Unresectable or Recurrent Gastric Cancer: A Single Center Experience
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Muranaka T, Yuki S, Komatsu Y, Sawada K, Harada K, Kawamoto Y, Nakatsumi , Sakamoto N
- KMID: 2372561
- J Gastric Cancer.
- 2016 Sep;16(3):177-181.
- doi: 10.5230/jgc.2016.16.3.177
PURPOSE: The International Organization for Standardization-5fluorouracil (FU) 10 trial found that bolus 5-FU and l-leucovorin was not inferior to S-1 in the treatment of gastric cancer (GC). Continuous 5-FU and... -
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- Splenomegaly and Its Associations with Genetic Polymorphisms and Treatment Outcome in Colorectal Cancer Patients Treated with Adjuvant FOLFOX
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Kim MJ, Han SW, Lee DW, Cha Y, Lee KH, Kim TY, Oh DY, Kim SH, Im SA, Bang YJ, Kim TY
- KMID: 2344072
- Cancer Res Treat.
- 2016 Jul;48(3):990-997.
- doi: 10.4143/crt.2015.296
PURPOSE: Splenomegaly is a clinical surrogate of oxaliplatin-induced sinusoidal obstruction syndrome (SOS). We investigated development of splenomegaly and its association with treatment outcome and genetic polymorphisms following adjuvant 5-fluorouracil, leucovorin,... -
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- Transanal Total Mesorectal Excision for Low Rectal Cancer
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Kim CW, Chung Y, Park SJ, Lee KY, Lee SH
- KMID: 2362242
- J Minim Invasive Surg.
- 2016 Jun;19(2):79-80.
- doi: 10.7602/jmis.2016.19.2.79
A 70-year-old female patient was diagnosed with low rectal adenocarcinoma (cT3N2) based on the initial CT and MRI. The patient underwent neoadjuvant chemoradiotherapy consisting of short course radiotherapy with 5-fluorouracil... -
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- Predictors of pathologic complete response after preoperative concurrent chemoradiotherapy of rectal cancer: a single center experience
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Choi E, Kim JH, Kim OB, Kim MY, Oh YK, Baek SG
- KMID: 2327383
- Radiat Oncol J.
- 2016 Jun;34(2):106-112.
- doi: 10.3857/roj.2015.01585
PURPOSE: To identify possible predictors of pathologic complete response (pCR) of rectal cancer after preoperative concurrent chemoradiotherapy (CCRT). MATERIALS AND METHODS: We conducted a retrospective review of 53 patients with rectal... -
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- Acute hyperammonemic encephalopathy after 5-fluorouracil based chemotherapy
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Yi HJ, Hong KS, Moon N, Chung SS, Lee RA, Kim KH
- KMID: 2155052
- Ann Surg Treat Res.
- 2016 Mar;90(3):179-182.
- doi: 10.4174/astr.2016.90.3.179
5-Fluorouracil (5-FU) based chemotherapy has been commonly used to treat metastatic or advanced colon cancer as an adjuvant chemotherapy. Although the side effects of 5-FU such as gastrointestinal problems and... -
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- p16 Hypermethylation and KRAS Mutation Are Independent Predictors of Cetuximab Plus FOLFIRI Chemotherapy in Patients with Metastatic Colorectal Cancer
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Kim SH, Park KH, Shin SJ, Lee KY, Kim TI, Kim NK, Rha SY, Roh JK, Ahn JB
- KMID: 2152277
- Cancer Res Treat.
- 2016 Jan;48(1):208-215.
- doi: 10.4143/crt.2014.314
PURPOSE: Hypermethylation of the CpG island of p16(INK4a) occurs in a significant proportion of colorectal cancer (CRC). We aimed to investigate its predictive role in CRC patients treated with 5-fluorouracil,... -
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- Primary Adenocarcinoma with Focal Choriocarcinomatous Differentiation in the Sigmoid Colon
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Oh SK, Kim HW, Kang DH, Choi CW, Choi YY, Lim HK, Goo JJ, Choi SY
- KMID: 2373360
- Korean J Gastroenterol.
- 2015 Nov;66(5):291-296.
- doi: 10.4166/kjg.2015.66.5.291
Primary colorectal choriocarcinoma is a rare neoplasm. Only 19 cases have been reported worldwide, most of which involved adenocarcinomas. The prognosis is usually poor, and the standard therapy for this... -
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- GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer
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Lee HY, Jung JH, Cho HM, Kim SH, Lee KM, Kim HJ, Lee JH, Shim BY
- KMID: 2403400
- Cancer Res Treat.
- 2015 Oct;47(4):804-812.
- doi: 10.4143/crt.2014.121
PURPOSE: We investigated the relationships between biomarkers related to endoplasmic reticulum stress proteins (glucose-regulated protein of molecular mass 78 [GRP78] and Cripto-1 [teratocarcinoma-derived growth factor 1 protein]), pathologic response, and... -
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- A Case of Advanced Gastric Cancer Presenting as Multiple Colonic Lymphoid Hyperplasia
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Lee IH, Lee J, Byeon SW, Lee H, Huo S, Yoon SB, Kim JS, Lee SH, Roh SY
- KMID: 2373345
- Korean J Gastroenterol.
- 2015 Oct;66(4):221-226.
- doi: 10.4166/kjg.2015.66.4.221
Gastric cancer frequently disseminates to the liver, lung, and bone via hematogeneous, lymphatic, or peritoneal routes. However, gastric adenocarcinoma that metastasize to the colon and that shows typical linea platisca... -
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- Efficacy and Safety of FOLFIRI after Failure of FOLFOX-4 in Advanced Gastric Cancer
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Kwon HJ, Park MI, Park SJ, Moon W, Kim SE, Lee HW, Choi YJ, Kim JH
- KMID: 2373306
- Korean J Gastroenterol.
- 2015 Jul;66(1):10-16.
- doi: 10.4166/kjg.2015.66.1.10
BACKGROUND/AIMS: The purpose of this study was to investigate the efficacy and safety of irinotecan based FOLFIRI chemotherapy as a second-line treatment after failure of FOLFOX-4 chemotherapy in patients with... -
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