- Delayed Elimination After High-dose Methotrexate in Pediatric Patients with Acute Lymphoblastic Leukemia and Non-Hodgkin Lymphoma
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Yoon HW, Ree YS, Song HS, Kim JS, Son ES
- KMID: 2452858
- Korean J Clin Pharm.
- 2019 Jun;29(2):101-108.
- doi: 10.24304/kjcp.2019.29.2.101
BACKGROUND: High doses of methotrexate (MTX) are often used in various chemotherapy protocols to treat acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL) in children, but its delayed elimination increases... -
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- Two Cases of Unresectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgical Resection
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Huh G, Chun JW, You MS, Paik WH, Lee SH, Kim YT, Ryu JK
- KMID: 2470444
- J Dig Cancer Rep.
- 2019 Dec;7(2):61-64.
- doi: 10.0000/jdcr.2019.7.2.61
We report two cases of patients with unresectable pancreatic cancer treated with neoadjuvant chemotherapy and surgical resection. In the first case, main mass was located at the neck of the... -
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- Protective effect of Korean red ginseng on oxaliplatin-mediated splenomegaly in colon cancer
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Kang J, Park JS, Ahn SG, Lim JH, Baik SH, Yoon DS, Lee KY, Jeong J
- KMID: 2419447
- Ann Surg Treat Res.
- 2018 Sep;95(3):161-167.
- doi: 10.4174/astr.2018.95.3.161
PURPOSE: This study investigated how adding Korean red ginseng extract (KRG) to folinic acid, fluorouracil and oxaliplatin (FOLFOX) chemotherapy affected the rate of splenomegaly in colon cancer. METHODS: This retrospective study... -
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- Hepatoid Carcinoma of the Pancreas Presenting as Acute Pancreatitis
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Shin SW, Sung YN, So H, Song E, Oh CR, Hong SM, Park DH
- KMID: 2435076
- Korean J Med.
- 2018 Aug;93(4):387-392.
- doi: 10.3904/kjm.2018.93.4.387
Hepatoid carcinoma is extrahepatic neoplasm showing similar morphologic, immunohistochemical features with hepatocellular carcinoma. It's a very rare disease and has been reported most frequently in the stomach. Herein, we report... -
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- Simultaneous integrated boost intensity-modulated radiotherapy versus 3-dimensional conformal radiotherapy in preoperative concurrent chemoradiotherapy for locally advanced rectal cancer
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Bae BK, Kang MK, Kim JC, Kim MY, Choi GS, Kim JG, Kang BW, Kim HJ, Park SY
- KMID: 2393550
- Radiat Oncol J.
- 2017 Sep;35(3):208-216.
- doi: 10.3857/roj.2017.00353
PURPOSE: To evaluate the feasibility of simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) for preoperative concurrent chemoradiotherapy (PCRT) in locally advanced rectal cancer (LARC), by comparing with 3-dimensional conformal radiotherapy (3D-CRT). MATERIALS... -
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- A Randomized Phase II Study of Leucovorin/5-Fluorouracil with or without Oxaliplatin (LV5FU2 vs. FOLFOX) for Curatively-Resected, Node-Positive Esophageal Squamous Cell Carcinoma
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Lim SH, Shim YM, Park SH, Kim HK, Choi YS, Ahn MJ, Park K, Zo JI, Sun JM
- KMID: 2388327
- Cancer Res Treat.
- 2017 Jul;49(3):816-823.
- doi: 10.4143/crt.2016.417
PURPOSE: The optimal perioperative treatment for resectable esophageal squamous cell carcinoma (ESCC) remains controversial. We evaluated the efficacy and safety of leucovorin and 5-fluorouracil (LV5FU2) and LV5FU2 plus oxaliplatin (FOLFOX)... -
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- FGFR4 Arg388 Is Correlated with Poor Survival in Resected Colon Cancer Promoting Epithelial to Mesenchymal Transition
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Cho SH, Hong CS, Kim HN, Shin MH, Kim KR, Shim HJ, Hwang JE, Bae WK, Chung IJ
- KMID: 2388322
- Cancer Res Treat.
- 2017 Jul;49(3):766-777.
- doi: 10.4143/crt.2016.457
PURPOSE: Fibroblast growth factor receptor 4 (FGFR4) plays an important role in cancer progression during tumor proliferation, invasion, and metastasis. This study evaluated the prognostic role of FGFR4 polymorphism in... -
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- Chemotherapy for Biliary Tract Cancer
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Woo SM
- KMID: 2383410
- Korean J Gastroenterol.
- 2017 Mar;69(3):172-176.
- doi: 10.4166/kjg.2017.69.3.172
The term of biliary tract cancer (BTC) refers to all tumors that arise from the biliary tract or the biliary drainage system, including the intra- and extra-hepatic bile ducts as... -
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- The outcomes of intensified 5-fluorouracil plus leucovorin chemotherapy for preoperative chemoradiation in rectal cancers
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Ha N, Hong KD, Ji WB, Kim JS, Um JW
- KMID: 2405657
- Korean J Clin Oncol.
- 2017 Dec;13(2):147-151.
- doi: 10.14216/kjco.17023
PURPOSE: The clinical benefit of intensified neoadjuvant chemoradiotherapy (CRT) in rectal cancer has not been proved. We investigated clinical outcomes of intensified 5-fluorouracil plus leucovorin (5-FU/LV) chemotherapy. METHODS: We retrospectively analyzed... -
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- Retrospective analysis on the clinical efficacy of bevacizumab combined with FOLFOX4 in the first line treatment of metastatic colorectal cancer
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Lee EM, Park LC, Lee HS, Shin SH, Kim YS
- KMID: 2400260
- Kosin Med J.
- 2017 Dec;32(2):170-178.
- doi: 10.7180/kmj.2017.32.2.170
OBJECTIVES: The addition of bevacizumab to standard chemotherapy has been improved survival outcomes in patients with metastatic colorectal cancer. However, the combination of bevacizumab with oxaliplatin-based chemotherapy as first-line treatment... -
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- Efficacy and Safety of Bolus 5-Fluorouracil and L-Leucovorin as Salvage Chemotherapy for Oral Fluoropyrimidine-Resistant Unresectable or Recurrent Gastric Cancer: A Single Center Experience
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Muranaka T, Yuki S, Komatsu Y, Sawada K, Harada K, Kawamoto Y, Nakatsumi , Sakamoto N
- KMID: 2372561
- J Gastric Cancer.
- 2016 Sep;16(3):177-181.
- doi: 10.5230/jgc.2016.16.3.177
PURPOSE: The International Organization for Standardization-5fluorouracil (FU) 10 trial found that bolus 5-FU and l-leucovorin was not inferior to S-1 in the treatment of gastric cancer (GC). Continuous 5-FU and... -
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- Splenomegaly and Its Associations with Genetic Polymorphisms and Treatment Outcome in Colorectal Cancer Patients Treated with Adjuvant FOLFOX
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Kim MJ, Han SW, Lee DW, Cha Y, Lee KH, Kim TY, Oh DY, Kim SH, Im SA, Bang YJ, Kim TY
- KMID: 2344072
- Cancer Res Treat.
- 2016 Jul;48(3):990-997.
- doi: 10.4143/crt.2015.296
PURPOSE: Splenomegaly is a clinical surrogate of oxaliplatin-induced sinusoidal obstruction syndrome (SOS). We investigated development of splenomegaly and its association with treatment outcome and genetic polymorphisms following adjuvant 5-fluorouracil, leucovorin,... -
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- Transanal Total Mesorectal Excision for Low Rectal Cancer
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Kim CW, Chung Y, Park SJ, Lee KY, Lee SH
- KMID: 2362242
- J Minim Invasive Surg.
- 2016 Jun;19(2):79-80.
- doi: 10.7602/jmis.2016.19.2.79
A 70-year-old female patient was diagnosed with low rectal adenocarcinoma (cT3N2) based on the initial CT and MRI. The patient underwent neoadjuvant chemoradiotherapy consisting of short course radiotherapy with 5-fluorouracil... -
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- Predictors of pathologic complete response after preoperative concurrent chemoradiotherapy of rectal cancer: a single center experience
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Choi E, Kim JH, Kim OB, Kim MY, Oh YK, Baek SG
- KMID: 2327383
- Radiat Oncol J.
- 2016 Jun;34(2):106-112.
- doi: 10.3857/roj.2015.01585
PURPOSE: To identify possible predictors of pathologic complete response (pCR) of rectal cancer after preoperative concurrent chemoradiotherapy (CCRT). MATERIALS AND METHODS: We conducted a retrospective review of 53 patients with rectal... -
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- Acute hyperammonemic encephalopathy after 5-fluorouracil based chemotherapy
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Yi HJ, Hong KS, Moon N, Chung SS, Lee RA, Kim KH
- KMID: 2155052
- Ann Surg Treat Res.
- 2016 Mar;90(3):179-182.
- doi: 10.4174/astr.2016.90.3.179
5-Fluorouracil (5-FU) based chemotherapy has been commonly used to treat metastatic or advanced colon cancer as an adjuvant chemotherapy. Although the side effects of 5-FU such as gastrointestinal problems and... -
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- p16 Hypermethylation and KRAS Mutation Are Independent Predictors of Cetuximab Plus FOLFIRI Chemotherapy in Patients with Metastatic Colorectal Cancer
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Kim SH, Park KH, Shin SJ, Lee KY, Kim TI, Kim NK, Rha SY, Roh JK, Ahn JB
- KMID: 2152277
- Cancer Res Treat.
- 2016 Jan;48(1):208-215.
- doi: 10.4143/crt.2014.314
PURPOSE: Hypermethylation of the CpG island of p16(INK4a) occurs in a significant proportion of colorectal cancer (CRC). We aimed to investigate its predictive role in CRC patients treated with 5-fluorouracil,... -
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- Efficacy and Safety of FOLFIRI after Failure of FOLFOX-4 in Advanced Gastric Cancer
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Kwon HJ, Park MI, Park SJ, Moon W, Kim SE, Lee HW, Choi YJ, Kim JH
- KMID: 2373306
- Korean J Gastroenterol.
- 2015 Jul;66(1):10-16.
- doi: 10.4166/kjg.2015.66.1.10
BACKGROUND/AIMS: The purpose of this study was to investigate the efficacy and safety of irinotecan based FOLFIRI chemotherapy as a second-line treatment after failure of FOLFOX-4 chemotherapy in patients with... -
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- Efficacy and Safety of FOLFIRI as Second-line Chemotherapy in Advanced Gastric Cancer
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Park SC, Chun HJ
- KMID: 2373304
- Korean J Gastroenterol.
- 2015 Jul;66(1):1-4.
- doi: 10.4166/kjg.2015.66.1.1
No abstract available. -
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- Rapidly Growing Interval Colon Cancer
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Kim JH, Park MI
- KMID: 2373231
- Korean J Gastroenterol.
- 2015 May;65(5):326-329.
- doi: 10.4166/kjg.2015.65.5.326
No abstract available. -
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- Primary Adenocarcinoma with Focal Choriocarcinomatous Differentiation in the Sigmoid Colon
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Oh SK, Kim HW, Kang DH, Choi CW, Choi YY, Lim HK, Goo JJ, Choi SY
- KMID: 2373360
- Korean J Gastroenterol.
- 2015 Nov;66(5):291-296.
- doi: 10.4166/kjg.2015.66.5.291
Primary colorectal choriocarcinoma is a rare neoplasm. Only 19 cases have been reported worldwide, most of which involved adenocarcinomas. The prognosis is usually poor, and the standard therapy for this... -
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