Korean J Med.  2012 May;82(5):537-542.

Postoperative Nausea and Vomiting

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. mdlhc@daum.net

Abstract

Postoperative nausea and vomiting (PONV) is considered as a main cause of dissatisfaction after surgery with postoperative pain. Overall incidence of PONV is 30%, and the incidence rate can increase up to 70-80% in high-risk patient groups. The causes of PONV are multifactorial and can largely be categorized as patient risk factors, surgical procedure, and anaesthetic technique. Pharmacological treatments including dopamine antagonist, anti-histamines, anticholinergics, dexamethasone, neurokinin-1 antagonists, and serotonin antagonist are used to prevent and treat PONV. This article reviews the prevalence, mechanisms, and risk factors of PONV, and how to prevent and treat it.

Keyword

Postoperative nausea and vomiting

MeSH Terms

Cholinergic Antagonists
Dexamethasone
Dopamine
Humans
Incidence
Pain, Postoperative
Postoperative Nausea and Vomiting
Prevalence
Risk Factors
Serotonin
Cholinergic Antagonists
Dexamethasone
Dopamine
Serotonin
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