Korean J Anesthesiol.  2014 Sep;67(3):164-170. 10.4097/kjae.2014.67.3.164.

Postoperative nausea and vomiting

  • 1Department of Anesthesiology and Pain Medicine, Seoul St. Mary's Hospital, Catholic University College of Medicine, Seoul, Korea. 0910momo@naver.com


Postoperative nausea and vomiting (PONV) is a long-standing issue, not a new concept in anesthesiology. Despite many studies over the last several decades, PONV remains a significant problem due to its complex mechanism. This review presents a summary of the mechanism underlying the pathogenesis of PONV, focusing on preventive treatment, particularly the use of new drugs. In addition, we discuss the latest meta-analysis results regarding correct clinical use of classic drugs. I also summarize the latest trends of postdischarge nausea and vomiting and the pharmacogenetics, which is attracting a great deal of attention from other medical fields in PONV-related studies. Finally, we discuss the drawbacks of existing studies on PONV and suggest a focus for future investigations.


Postdischarge nausea and vomiting; Postoperative nausea and vomiting; Prevention

MeSH Terms

Postoperative Nausea and Vomiting*

Cited by  1 articles

Postoperative nausea and vomiting in patients undergoing colorectal surgery within an institutional enhanced recovery after surgery protocol: comparison of two prophylactic antiemetic regimens
Jennifer Holder-Murray, Stephen A Esper, Michael L Boisen, Julie Gealey, Katie Meister, David S Medich, Kathirvel Subramaniam
Korean J Anesthesiol. 2019;72(4):344-350.    doi: 10.4097/kja.d.18.00355.

Full Text Links
  • KJAE
export Copy
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr