Korean J Anesthesiol.  2014 Sep;67(3):164-170. 10.4097/kjae.2014.67.3.164.

Postoperative nausea and vomiting

• Moon YE

• KMID: 1966749
• DOI: http://doi.org/10.4097/kjae.2014.67.3.164

Abstract

Postoperative nausea and vomiting (PONV) is a long-standing issue, not a new concept in anesthesiology. Despite many studies over the last several decades, PONV remains a significant problem due to its complex mechanism. This review presents a summary of the mechanism underlying the pathogenesis of PONV, focusing on preventive treatment, particularly the use of new drugs. In addition, we discuss the latest meta-analysis results regarding correct clinical use of classic drugs. I also summarize the latest trends of postdischarge nausea and vomiting and the pharmacogenetics, which is attracting a great deal of attention from other medical fields in PONV-related studies. Finally, we discuss the drawbacks of existing studies on PONV and suggest a focus for future investigations.

Keyword

Postdischarge nausea and vomiting; Postoperative nausea and vomiting; Prevention

MeSH Terms

Anesthesiology
Nausea
Pharmacogenetics
Postoperative Nausea and Vomiting*
Vomiting