Korean J Med.  2012 Jun;82(6):764-768.

Renal Parenchymal Malakoplakia Presenting with Abscesses and Hepatic Extension Misdiagnosed as a Malignant Tumor: A Case Report

• Yoon SY
• Lee HJ
• An JH
• Kim SJ
• Kim SW
• Woo JH
• Kim YS

Abstract

Malakoplakia is a chronic inflammatory disorder that usually affects the urinary tract in immunocompromised patients and rarely extends to adjacent organs. Due to its mass-like presentation, malakoplakia is often clinically misdiagnosed as a neoplastic lesion. We describe the case of a 51-year-old female with renal malakoplakia and hepatic extension and large intraperitoneal abscesses that had been misdiagnosed as malignancy. She was diagnosed with myasthenia gravis 12 years prior and had been treated with oral corticosteroids and immunosuppressants. Radical nephrectomy concomitant with abscess drainage was performed. The final pathology was compatible with malakoplakia, and the patient was successfully treated with antibiotics. Although renal malakoplakia is a rare disease, it should be included in the differential diagnosis of patients with a renal mass who have a history of recurrent urinary tract infections or evidence of immunosuppression.

Keyword

Kidney; Liver; Malakoplakia

MeSH Terms

Abscess
Adrenal Cortex Hormones
Anti-Bacterial Agents
Diagnosis, Differential
Drainage
Female
Humans
Immunocompromised Host
Immunosuppression
Immunosuppressive Agents
Kidney
Liver
Malacoplakia
Middle Aged
Myasthenia Gravis
Nephrectomy
Rare Diseases
Urinary Tract
Urinary Tract Infections
Adrenal Cortex Hormones
Anti-Bacterial Agents
Immunosuppressive Agents