Korean J Med.  2010 Oct;79(4):417-421.

Veratrum patulum intoxication developed in a group of twenty-three patients

Affiliations
  • 1Department of Internal Medicine, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea. gi@gnah.co.kr
  • 2Department of Emergency Medicine, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea.

Abstract

Veratrum patulum is a perennial plant with toxicity, which grows wild in the high mountain areas of Korea. Various types of steroidal alkaloids contained in Veratrum patulum are known to cause symptoms such as nausea, vomiting, bradycardia and hypotension. Twenty-three patients were admitted to our center with chief complaints of nausea and vomiting after ingesting leaves of Veratrum patulum. The mean age of the group was 44 years old and was comprised of 19 males and 4 females. Some patients showed hypotension and bradycardia with symptoms such as dizziness. Ten patients with severe bradycardia coupled with other symptoms received atropine administration. Nausea and vomiting were improved after the administration of anti-emetics. Blood pressure and the pulse rate were all normalized on the day after admission, and all of the patients were discharged without any symptoms.

Keyword

Veratrum patulum; Steroidal alkaloid; Bradycardia

MeSH Terms

Alkaloids
Antiemetics
Atropine
Blood Pressure
Bradycardia
Dizziness
Female
Heart Rate
Humans
Hypotension
Korea
Male
Nausea
Plants
Veratrum
Vomiting
Alkaloids
Antiemetics
Atropine
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