- Chemical Constituents of Bark of Beilschmiedia kunstleri Gamble with Anticancer, Anti-Streptococcus pyogenes, Anti-Bacillus cereus and Anti Plesiomonas shigelloides Activities
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Mollataghi A
- KMID: 2443097
- Nat Prod Sci.
- 2019 Mar;25(1):11-15.
- doi: 10.20307/nps.2019.25.1.11
Lauraceae is a family medicinal plant whose tubers possesses antimicrobial, and cytotoxic, such as antiparasitic and anti-inflammatory special effects and has been used for the medicine in the cure of... -
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- Adverse Factors and the Role of Cisplatin and Vinca Alkaloids for Hearing Impairment in Childhood Cancer Patients and Survivors
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Hur MW, Hahn SM, Moon IS, Lim JY, Lee SM, Lyu CJ, Han JW
- KMID: 2396013
- Clin Pediatr Hematol Oncol.
- 2017 Oct;24(2):121-129.
- doi: 10.15264/cpho.2017.24.2.121
BACKGROUND: Although combined chemotherapy has increased survival rates among children with cancer, such treatments can induce sensorineural hearing loss. Therefore, we aimed to identify risk factors for hearing impairments in... -
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- Antioxidant and Antiaging Assays of Hibiscus sabdariffa Extract and Its Compounds
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Widowati W, Rani AP, Hamzah RA, Arumwardana S, Afifah E, Kusuma HS, Rihibiha D, Nufus H, Amalia A
- KMID: 2393800
- Nat Prod Sci.
- 2017 Sep;23(3):192-200.
- doi: 10.20307/nps.2017.23.3.192
Skin aging is a complex biological process due to intrinsic and extrinsic factors. Free radical oxidative is one of extrinsic factors that induce activation of collagenase, elastase and hyaluronidase. Natural... -
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- New Azafluorenone Derivative and Antibacterial Activities of Alphonsea cylindrica Barks
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Talip MA, Azziz SS, Wong CF, Awang K, Naz H, Bakri YM, Ahmad MS, Litaudon M
- KMID: 2393794
- Nat Prod Sci.
- 2017 Sep;23(3):151-156.
- doi: 10.20307/nps.2017.23.3.151
A phytochemical study of Alphonsea cylindrica King (unreported) has led to the isolation of six alkaloids. The compounds were identified as kinabaline (1; azafluorenone alkaloid), muniranine (2), O-methylmoschatoline (3; oxoaporphine... -
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- Aldose Reductase Inhibitory Alkaloids from Corydalis ternata
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Seo W, Jung SH, Shim SH
- KMID: 2328874
- Nat Prod Sci.
- 2016 Jun;22(2):102-106.
- doi: 10.20307/nps.2016.22.2.102
A methanolic extract of Corydalis ternata having aldose reductase inhibitory activity was examined as a possible aldose reductase (ALR2) inhibitor, a key enzyme involved in diabetic complications. Seven alkaloids, tetrahydrocoptisine... -
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- A Novel Bromoindole Alkaloid from a Korean Colonial Tunicate Didemnum sp.
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Hahn D, Kim GJ, Choi H, Kang H
- KMID: 2312910
- Nat Prod Sci.
- 2015 Dec;21(4):278-281.
- doi: 10.20307/nps.2015.21.4.278
Chemical investigation on a colonial marine tunicate, Didemnum sp. led to the isolation of a series of indole alkaloids including a new (1) and two known metabolites (2-3). Based on... -
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- Pharmacodynamic Drug-Drug Interactions Considered to be Added in the List of Contraindications with Pharmacological Classification in Korea
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Je NK, Kim DS, Kim GJ, Lee S
- KMID: 2068835
- Korean J Clin Pharm.
- 2015 Jun;25(2):120-128.
- doi: 10.0000/kjcp.2015.25.2.120
OBJECTIVES: Drug utilization review program in Korea has provided 'drug combinations to avoid DCA)' alerts to physicians and pharmacists to prevent potential adverse drug events or inappropriate drug use. Seven... -
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- Recent Updates on Chemotherapy-Induced Peripheral Neuropathy
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Woo IS
- KMID: 2269167
- Korean J Med.
- 2015 Jan;88(1):35-37.
- doi: 10.3904/kjm.2015.88.1.35
Chemotherapy induced peripheral neuropathy (CIPN) could debilitate the quality of life in the patients with cancer. According to the severity of CIPN, the modification of dosage of chemotherapeutic agents and... -
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- Intractable Ventricular Arrhythmia Induced by Aconite and its Successful Treatment with Extracorporeal Membrane Oxygenation Support
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Kim YJ, Kim OG, Jang JG, Rhee I, Kim WY
- KMID: 2333904
- J Korean Soc Emerg Med.
- 2014 Aug;25(4):471-475.
- doi: 10.0000/jksem.2014.25.4.471
Aconite, derived from the roots of certain aconitum species (Racunculaceae), is widely distributed in Korea. Aconitine, an extremely toxic substance present in aconite, has pharmacological effects, including anti-inflammatory, analgesic, and... -
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- Hepatic Sinusoidal Obstruction Syndrome Caused by Herbal Medicine: CT and MRI Features
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Zhou H, Wang YX, Lou HY, Xu XJ, Zhang MM
- KMID: 1705576
- Korean J Radiol.
- 2014 Apr;15(2):218-225.
- doi: 10.3348/kjr.2014.15.2.218
OBJECTIVE: To describe the CT and MRI features of hepatic sinusoidal obstruction syndrome (HSOS) caused by herbal medicine Gynura segetum. MATERIALS AND METHODS: The CT and MRI features of 16 consecutive... -
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- Possible Role of Sonic Hedgehog and Epithelial-Mesenchymal Transition in Renal Cell Cancer Progression
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Behnsawy H, Shigemura , Meligy FY, Yamamichi , Yamashita , Haung WC, Li X, Miyake H, Tanaka K, Kawabata M, Shirakawa , Fujisawa M
- KMID: 1840469
- Korean J Urol.
- 2013 Aug;54(8):547-554.
- doi: 10.4111/kju.2013.54.8.547
PURPOSE: Sonic hedgehog (Shh) signaling and epithelial-mesenchymal transition (EMT) are both known to relate to cancer progression. The purpose of this study was to investigate the role of Shh signaling... -
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- Two Cases of Poisoning with Veratrum Maackii
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Sung WY, Kim YH, Lee JY, Park GN, Lee WS, Yang YM
- KMID: 2333212
- J Korean Soc Emerg Med.
- 2012 Oct;23(5):738-741.
Veratrum alkaloids in Veratrum maackii may cause significant gastrointestinal symptoms, bradycardia, hypotension, and arrythmia. We experienced successful outcomes in two patients who were victims of poisoning due to ingestion of... -
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- Comparison with human amniotic membrane- and adipose tissue-derived mesenchymal stem cells
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Hwang IS, Kim HG, Jo DH, Lee DH, Koo YH, Song YJ, Na YJ, Choi OH
- KMID: 2274106
- Korean J Obstet Gynecol.
- 2011 Nov;54(11):674-683.
- doi: 10.5468/KJOG.2011.54.11.674
OBJECTIVE: Mesenchymal stem cells (MSC) have been considered as an ideal source of stem cells because of low immunogenicity and availability of autologous cells. Although it has been reported that... -
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- Veratrum patulum intoxication developed in a group of twenty-three patients
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Lee SH, Kim YD, Ha DC, Han KH, Jeong WJ, Kang HD, Cheon GJ
- KMID: 2259345
- Korean J Med.
- 2010 Oct;79(4):417-421.
Veratrum patulum is a perennial plant with toxicity, which grows wild in the high mountain areas of Korea. Various types of steroidal alkaloids contained in Veratrum patulum are known to... -
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- The Toxicological Studies and Autopsy Findings of Aconitine Poisoning
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Choi HK, Kim YS, Choi IS, Kim JH
- KMID: 2305496
- Korean J Leg Med.
- 2010 May;34(1):15-19.
BACKGROUND: Aconitium species have been used for a material of oriental herb medicine for analgesic and anti-inflammatory effects. But Aconitium species were known to have the potent poisons like aconitine,... -
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- Anticholinergic Toxicity Following Ingestion of Angel's Trumpet: A Case Report
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Kim H, Kim JS, Chung JM
- KMID: 2192633
- J Korean Soc Emerg Med.
- 2009 Dec;20(6):729-731.
Angel's trumpet is a poisonous shrub recently imported to Korea for ornamental PURPOSE. It contains tropane alkaloids and the ingestion of any part of the plant can cause serious anticholinergic... -
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- Trends in the incidence of ulcerative colitis in Korea
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Yang DH, Yang SK
- KMID: 2257255
- Korean J Med.
- 2009 Jun;76(6):637-642.
Ulcerative colitis is an idiopathic chronic inflammatory disease of the colon that has traditionally been considered rare in Korea. The incidence of ulcerative colitis, however, has increased recently. According to... -
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- Cytosolic accumulation of gammaH2AX is associated with tropomyosin-related kinase A-induced cell death in U2OS cells
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Jung EJ, Kim CW, Kim DR
- KMID: 756329
- Exp Mol Med.
- 2008 Jun;40(3):276-285.
- doi: 10.3858/emm.2008.40.3.276
Tropomyosin-related kinase A (TrkA) plays an important role in cell survival, differentiation, and apoptosis in various neuronal and nonneuronal cell types. Here we show that TrkA overexpression by the Tet-On... -
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- Salsolinol in the Pathophysiology of Alcohol Dependence and Parkinson's Disease
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Chung IW, Jeong SH, Kim JY
- KMID: 2341438
- J Korean Neuropsychiatr Assoc.
- 2008 May;47(3):217-224.
Salsolinol, a dopamine-derived tetrahydroisoquinoline, is one of the endogenous alkaloids structurally related to morphine. It has been implicated in the pathophysiology of alcohol dependence and Parkinson's disease since it's first... -
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- An Autopsy Case of Postpartum Acute Myocardial Infarction Associated with Postpartum Ergot Alkaloids Administration in Old-Aged Pregnant Women
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Eom M, Lee JH, Chung JH, Lee H
- KMID: 2428307
- Yonsei Med J.
- 2005 Dec;46(6):866-869.
Cases of acute myocardial infarction (AMI) that occur during pregnancy or postpartum are rarely reported. Ergot derivatives are known to induce the spasmodic contraction of coronary arteries. Administration of ergot... -
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