Korean J Med.  2006 Dec;71(6):688-693.

Efficiency of positron-emission tomography in two cases of idiopathic retroperitoneal fibrosis

Affiliations
  • 1Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, Korea. hughkim@ajou.ac.kr
  • 2Department of Nuclear Medicine, Ajou University School of Medicine, Suwon, Korea.

Abstract

Idiopathic retroperitoneal fibrosis is a relatively rare disease that is characterized by the proliferation of fibrous tissue with an inflammatory process in the retroperitoneal cavity. It can cause an obstruction and compression of the ureter, abdominal aorta, and finally progress to renal failure. During the initial stages, the histology shows active inflammation. However, in the late stages, fibrous scarring occurs and the tissue becomes relatively avascular and acellular. Increased 18F-FDG accumulation was observed in our patient at the time of disease onset, which was attributed to the presence of inflammatory cells and actively metabolizing fibroblasts. We describe two patients with idiopathic retroperitoneal fibrosis, who were examined by 18F-FDG-PET, and discuss the efficiency of positron emission tomography in the diagnosis and management of idiopathic retroperitoneal fibrosis patients.

Keyword

Idiopathic Retroperitoneal fibrosis; Positron-emission tomography

MeSH Terms

Aorta, Abdominal
Cicatrix
Diagnosis
Fibroblasts
Fluorodeoxyglucose F18
Humans
Inflammation
Positron-Emission Tomography*
Rare Diseases
Renal Insufficiency
Retroperitoneal Fibrosis*
Ureter
Fluorodeoxyglucose F18
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