- Proteomic Classification and Identification of Proteins Related to Tissue Healing of Platelet-Rich Plasma
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Lee HW, Choi KH, Kim JY, Kim KO, Haotian B, Yuxuan L, Noh KC
- KMID: 2470060
- Clin Orthop Surg.
- 2020 Mar;12(1):120-129.
- doi: 10.4055/cios.2020.12.1.120
BACKGROUND: Platelet-rich plasma (PRP) is a plasma component of autologous blood containing a high concentration of platelets. PRP is used to promote healing of damaged tissues. However, there are not... -
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- Current Understanding of Mineral and Bone Disorders of Chronic Kidney Disease and the Scientific Grounds on the Use of Exogenous Parathyroid Hormone in Its Management
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Pazianas M, Miller PD
- KMID: 2471309
- J Bone Metab.
- 2020 Feb;27(1):1-13.
- doi: 10.11005/jbm.2020.27.1.1
Chronic Kidney disease (CKD) disturbs mineral homeostasis leading to mineral and bone disorders (MBD). Serum calcium and phosphate (Pi) remain normal until the late stages of CKD at the expense... -
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- Fibroblast Growth Factor 21 Attenuates Diabetes-Induced Renal Fibrosis by Negatively Regulating TGF-β-p53-Smad2/3-Mediated Epithelial-to-Mesenchymal Transition via Activation of AKT
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Lin S, Yu L, Ni Y, He L, Weng X, Lu X, Zhang C
- KMID: 2470964
- Diabetes Metab J.
- 2020 Feb;44(1):158-172.
- doi: 10.4093/dmj.2018.0235
BACKGROUND: Epithelial-to-mesenchymal transition (EMT) is required for renal fibrosis, which is a characteristic of diabetic nephropathy (DN). Our previous study demonstrated that fibroblast growth factor 21 (FGF21) prevented DN associated... -
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- Cytocompatibility and cell proliferation evaluation of calcium phosphate-based root canal sealers
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Mestieri L, Zaccara IM, Pinheiro L, Barletta F, Kopper PM, Grecca FS
- KMID: 2470338
- Restor Dent Endod.
- 2020 Feb;45(1):e2.
- doi: 10.5395/rde.2020.45.e2
OBJECTIVES: This study aimed to evaluate the cell viability and migration of Endosequence Bioceramic Root Canal Sealer (BC Sealer) compared to MTA Fillapex and AH Plus. MATERIALS AND METHODS: BC Sealer,... -
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- Ultrasound and MRI Findings of Giant Cell Fibroblastoma in the Abdominal Wall: Radiologic-Pathologic Correlations
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Min S, Park SY, Seo J, Koh SH, Lee K
- KMID: 2469200
- J Korean Soc Radiol.
- 2020 Jan;81(1):237-242.
- doi: 10.3348/jksr.2020.81.1.237
Giant cell fibroblastoma (GCF) is a rare soft-tissue sarcoma of fibroblastic origin. To the best of our knowledge, only one brief description of the MRI findings of GCF exists in... -
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- Derivation of endothelial cells from porcine induced pluripotent stem cells by optimized single layer culture system
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Wei R, Lv J, Li X, Li Y, Xu Q, Jin J, Zhang Y, Liu Z
- KMID: 2469024
- J Vet Sci.
- 2020 Jan;21(1):e9.
- doi: 10.4142/jvs.2020.21.e9
Regenerative therapy holds great promise in the development of cures of some untreatable diseases such as cardiovascular diseases, and pluripotent stem cells (PSCs) including induced PSCs (iPSCs) are the most... -
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- Plasma Fibroblast Growth Factor 23 Concentration Is Associated with Intracranial Cerebral Atherosclerosis in Acute Ischemic Stroke Patients
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Chang Y, Kim J, Woo HG, Ryu DR, Oh HJ, Song TJ
- KMID: 2467781
- J Clin Neurol.
- 2020 Jan;16(1):29-36.
- doi: 10.3988/jcn.2020.16.1.29
BACKGROUND AND PURPOSE: Fibroblast growth factor 23 (FGF23) is associated with atherosclerosis via nitric-oxide-associated endothelial dysfunction and calcium-phosphate-related bone mineralization. This study aimed to determine the association of the plasma... -
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- Follistatin Mitigates Myofibroblast Differentiation and Collagen Synthesis of Fibroblasts from Scar Tissue around Injured Flexor Tendons
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Kang YM, Lee SK, Chun YM, Choi YR, Moon SH, Lee HM, Kang HJ
- KMID: 2466340
- Yonsei Med J.
- 2020 Jan;61(1):85-93.
- doi: 10.3349/ymj.2020.61.1.85
PURPOSE: The aim of this study was to investigate the effect of FST gene on the inhibition of fibrosis in fibroblastic cells from scar tissue around repaired zone II flexor... -
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- Involvement of immune responses in pulmonary arterial hypertension; lessons from rodent models
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Kim K, Choi JH
- KMID: 2470011
- Lab Anim Res.
- 2019 Dec;35(4):148-153.
- doi: 10.1186/s42826-019-0021-1
Pulmonary hypertension (PH) is a pathological state with sustained elevation of pulmonary artery (PA) pressure. Since the pathogenesis of PH is mostly irreversible, the disease often comes up with poor... -
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- Regulatory Pathway of Ion-Transporter Genes through Nrf2 Transcription Factor in Hypokalemic Condition
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Cho HJ, Ahn KY
- KMID: 2467467
- Anat Biol Anthropol.
- 2019 Dec;32(4):141-149.
- doi: 10.11637/aba.2019.32.4.141
The Nuclear factor-erythroid-2-related factor 2 (Nrf2) plays a key role in the cellular defense against oxidative stress. Low K+ increased the reactive oxygen species and it stimulate Nrf2 activation. Previous... -
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- Metformin-loaded Citric Acid Cross-linked Agarose Films in the Prevention of Postoperative Abdominal Adhesion
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Moon JH, Park JH, Jeong JH, Sung NS, Jeong YG, Song KC, Ahn JP, Lee NS, Han SY
- KMID: 2467466
- Anat Biol Anthropol.
- 2019 Dec;32(4):129-139.
- doi: 10.11637/aba.2019.32.4.129
Postoperative abdominal adhesion (PAA) causes significant long-term postoperative morbidity. Although numerous physical anti-adhesion barriers (AAB) are used as therapeutical interventions, none of them has achieved sustained success. As a potential... -
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- Chemical Regeneration of Wound Defects: Relevance to the Canine Palatal Mucosa and Cell Cycle Up-Regulation in Human Gingival Fibroblasts
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Lee K, Ben Amara , Lee SC, Leesungbok R, Chung MA, Koo KT, Lee SW
- KMID: 2467059
- Tissue Eng Regen Med.
- 2019 Dec;16(6):675-684.
- doi: 10.1007/s13770-019-00227-6
BACKGROUND: Trichloroacetic acid (TCA) is an agent widely applied in dermatology for skin regeneration. To test whether TCA can offer an advantage for the regeneration of oral soft tissue defects,... -
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- Development of Macroporous Chitosan Scaffolds for Eyelid Tarsus Tissue Engineering
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Sun MT, O'Connor A, Milne I, Biswas D, Casson R, Wood J, Selva D
- KMID: 2467052
- Tissue Eng Regen Med.
- 2019 Dec;16(6):595-604.
- doi: 10.1007/s13770-019-00201-2
BACKGROUND: Reconstruction of large eyelid defects remains challenging due to the lack of suitable eyelid tarsus tissue substitutes. We aimed to evaluate a novel bioengineered chitosan scaffold for use as... -
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- Direct Reprogramming to Human Induced Neuronal Progenitors from Fibroblasts of Familial and Sporadic Parkinson’s Disease Patients
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Lee M, Sim H, Ahn H, Ha J, Baek A, Jeon YJ, Son MY, Kim J
- KMID: 2465888
- Int J Stem Cells.
- 2019 Nov;12(3):474-483.
- doi: 10.15283/ijsc19075
In Parkinson’s disease (PD) research, human neuroblastoma and immortalized neural cell lines have been widely used as in vitro models. The advancement in the field of reprogramming technology has provided... -
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- Reprogramming of Cancer Cells into Induced Pluripotent Stem Cells Questioned
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Bang JS, Choi NY, Lee M, Ko K, Park YS, Ko K
- KMID: 2465883
- Int J Stem Cells.
- 2019 Nov;12(3):430-439.
- doi: 10.15283/ijsc19067
BACKGROUND AND OBJECTIVES: Several recent studies have claimed that cancer cells can be reprogrammed into induced pluripotent stem cells (iPSCs). However, in most cases, cancer cells seem to be resistant... -
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- CT and MRI Features of Solitary Fibrous Tumor of the Liver: A Case Report
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Nah YK, Shin SS, Heo SH, Jeong YY
- KMID: 2464923
- J Korean Soc Radiol.
- 2019 Nov;80(6):1253-1257.
- doi: 10.3348/jksr.2019.80.6.1253
Solitary fibrous tumors (SFTs) are a unique group of soft tissue tumors originating from fibroblastic or myofibroblastic tissue. SFTs rarely occur in the liver, with less than 30 cases reported... -
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- Viperin Differentially Induces Interferon-Stimulated Genes in Distinct Cell Types
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Kim JJ, Kim KS, Eom J, Lee JB, Seo JY
- KMID: 2461197
- Immune Netw.
- 2019 Oct;19(5):e33.
- doi: 10.4110/in.2019.19.e33
Viperin is an IFN-stimulated gene (ISG)-encoded protein that was identified in human primary macrophages treated with IFN-γ and in human primary fibroblasts infected with cytomegalovirus (CMV). This protein plays multiple... -
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- Role of Hydrogen Sulfide in the Survival of Fibroblasts and Fibroblast-mediated Contraction of Collagen Gel
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Park HJ, Kim JW
- KMID: 2460516
- J Korean Ophthalmol Soc.
- 2019 Oct;60(10):975-981.
- doi: 10.3341/jkos.2019.60.10.975
PURPOSE: To investigate the role of hydrogen sulfide in the survival and collagen gel contraction of cultured human Tenon's capsule fibroblasts (HTCFs). METHODS: Primarily cultured HTCFs were exposed to 0, 100,... -
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- The Clinical Uses of Collagen-Based Matrices in the Treatment of Chronic Wounds
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Yang HJ, Kang SY
- KMID: 2465852
- J Wound Manag Res.
- 2019 Sep;15(2):103-108.
- doi: 10.22467/jwmr.2019.00640
Chronic wounds are defined as wounds that fail to heal completely at the pace and order observed in normal phases of wound healing. Whereas acute wounds proceed through the normal... -
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- Immunohistochemical Expression of Epithelial-Mesenchymal Transition Markers in Early Gastric Cancer: Cancer Tissue versus Noncancer Tissue
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Jung HJ, Hong SJ, Kim SH
- KMID: 2464668
- Clin Endosc.
- 2019 Sep;52(5):464-471.
- doi: 10.5946/ce.2018.181
BACKGROUND/AIMS: Epithelial-mesenchymal transition (EMT) is a developmental process, wherein the epithelial cells show reduced intercellular adhesions and acquire migratory fibroblastic properties. EMT is associated with downregulation in epithelial marker expression,... -
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